Get

In Your Inbox

Catster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

Why Do Kittens Sometimes Die Suddenly? Vet-Verified Causes & Facts

Share

newborn kitten in man's hand

Having a litter of newborn kittens in your house can be a cause for celebration, but it can sometimes also cause heartache. These tiny little bundles of fluff are incredibly fragile, and sometimes you might wake up to find that a kitten died overnight.

Sadly, it’s a common occurrence that out of a litter, a kitten may die suddenly. This percentage is often higher in purebred cats, with research showing that the Persian breed often has the highest mortality rates for kittens.

Knowing the subtle signs to look out for can mean that you can give your kittens the best chance of survival. We outlined the main reasons for sudden kitten death here, as well as what you can do to prevent it.

divider single cat paw oct 2024

What Are Fading Kittens?

The term given to kittens dying between birth and when they’re weaned is “fading kittens.” This is a fairly common occurrence, although it is very sad whenever it happens. Professional breeders will usually prepare themselves for the chance that some of their kittens may not survive up to weaning, but it can be harder to prepare for if this is your cat’s first litter.

The highest risk period for kittens is their first week of life. After they’re more than 7 days old, the risk of death starts to decrease dramatically, but they’re still considered at risk until after they’ve been weaned.

The 3 Causes of Fading Kittens

1. Hypothermia

Newborn kittens can’t regulate their own body temperature, so they are at high risk of becoming too cold and developing hypothermia. Kittens rely on their mothers to keep them warm, but they may also benefit from a heating pad or heat lamp. If a kitten falls out of the nest or moves away from their mother, they can quickly become too cold. Hypothermia can cause lower respiratory and heart rates, which if left untreated, can lead to cardiovascular failure.

Once a kitten is cold, they also usually stop suckling milk, which means their bodies are under even more stress. It’s a good idea to make sure that you provide heat sources for newborn kittens and monitor their temperatures. Use a thermometer to take each kitten’s rectal temperature, and keep a note of their levels. Newborn kittens should have a temperature of 95–97 degrees Fahrenheit, increasing to 100 degrees Fahrenheit by the time they’re a week old. During this time, keep their environment at 85–90 degrees Fahrenheit.

mother cat with kittens
Image by: Karen Hogan, Shutterstock

2. Hypoglycemia (Low Blood Sugar)

Newborn kittens need plenty of nutrients, but their small body size means they have no natural reserves to use. This means they need to drink a large amount of milk from their mother or via a milk replacement formula. If they don’t get enough milk, their blood sugar levels can rapidly drop and they can become hypoglycemic.

Signs of hypoglycemia include:
  • Weakness
  • Low body temperature
  • Difficulty breathing
  • Crying and mewling
  • Seizures

Left untreated, hypoglycemia can lead to coma and death.

bottle feeding a tabby kitten
Image by: Adina Voicu, Pixabay

3. Dehydration

Kitten’s bodies have a high water content, but they’re not yet able to effectively regulate this, so they can quickly lose water through their lungs, skin, and kidneys. If they don’t replace this lost water, they can quickly become dehydrated. Diarrhea can rapidly cause a kitten to become dehydrated, too.

Signs of dehydration include:
  • Lack of energy
  • Dry gums
  • Panting
  • Sunken eyes
  • Skin sticking in place when pulled upward

Dehydrated kittens may need subcutaneous fluids to help them recover.

divider single cat paw oct 2024

Causes of Death Related to Birth & the Mother Cat

Sometimes, kittens can die suddenly as a result of birth complications or issues connected to the health of the mother cat.

1. Difficult Birth

If a mother cat’s labor was traumatic, this can cause a range of problems, which can cause kittens to die suddenly. Lack of oxygen (hypoxia) during birth can lead to kittens dying shortly after birth. Certain breeds, including those with flat faces, like Persians, are known to suffer birthing difficulties, which can affect the health of the kittens.

mother cat gave birth to kitten
Image by: Azami Adiputera, Shutterstock

2. Experience of the Mother Cat

The first litter of any mother cat is often more at risk than subsequent litters. An inexperienced mother cat may have a more traumatic birth. As mother cats have more litters though, the risk can increase again. Litters two through four are most likely to be born without complications. If the mother cat doesn’t feed her kittens correctly, they can miss out on the vital first milk known as colostrum.

This contains antibodies that help boost a kitten’s immune system so they can fight off infection and disease.


3. Health of the Mother Cat

If the mother cat is obese, this can sometimes cause increased kitten mortality. Other health conditions, including mastitis or reduced milk supply, will also affect the health of the kittens.

mother cat giving birth to a child
Image by: Akhmad Sopiyan, Shutterstock

4. Inappropriate Environment

Even kittens that initially seem healthy can quickly fade and die if their environment isn’t correct.

Be sure to check the following factors:
  • For the first week of life, a kitten’s environment should be kept at between 85–90 degrees Fahrenheit. After 1 week, it can then be dropped to 85 degrees Fahrenheit. From 2 weeks onward, aim for 80 degrees Fahrenheit, decreasing to 75 degrees Fahrenheit at 3 weeks. From 1 month, aim for 70–75 degrees Fahrenheit.
  • If the nest is dirty and soiled, this can increase the risk of infectious diseases.
  • While it can be tempting to cuddle those tiny kittens all the time, this can be stressful for both them and their mother cat. Kittens can easily get too cold if away from the warmth of their mother. Unfamiliar smells may cause an inexperienced or timid mother cat to abandon her babies.

5. Congenital Abnormalities

Certain physical defects can develop while a kitten is still in the womb, and these are known as congenital abnormalities. These can either be inherited or developmental.

Common examples are:
  • Umbilical hernia
  • Cleft palate
  • Skeletal defects

Severe congenital abnormalities will usually cause the death of a kitten before they’re born, or they will die shortly after birth. Sometimes these defects will be obvious, while other times, you may want to ask your vet to help you identify them if possible.

Less severe abnormalities may result in some of the symptoms of fading kittens. The risks for certain congenital abnormalities can increase if breeders don’t carefully screen their cats for health conditions or if they breed cats that are too closely related. For that reason, if you’re choosing a purebred kitten, it’s always important to select a reputable breeder with a strong breeding program, including health tests on the parent cats and the kittens.

mother cat giving birth to her child
Image by: Goldziitfotografie, Shutterstock

6. Low Birth Weight or Poor Nutrition

Kittens with a low birth weight are at a higher risk of death. Most newborn kittens should weigh between 50-150 grams, although this will vary depending on the breed. Kittens with a low birth weight may need support from kitten milk replacement formula to help them gain weight. They’re also at higher risk of developing dehydration, hypothermia, infections, or respiratory failure, so close attention needs to be paid to their health.

Kittens should be weighed when they’re born, then once a day for the first 7 days and once a week thereafter. They should gain 5–10% of their body weight per day and have doubled their birth weight after 2 weeks.

If kittens aren’t gaining weight, you may need to supplement their mother’s milk with kitten milk replacement formula. Speak to a vet for advice on how exactly to do this and about the proper milk/replacement ratio.

Need veterinary advice but can't get to the clinic? Catster recommends PangoVet, our online veterinary service. Talk to a vet online and get the answers and advice you need for your cat without having to leave your living room — all at an affordable price!

PangoVet_Mention-in-Content for PangoVet2 save money


7. Infections

A kitten’s immune system can be compromised by a few different factors, including a lack of colostrum, low birth weight, or a lack of oxygen at birth. This can increase the risk of them contracting an infection. The most common infections seen in kittens include:

Systemic diseases
  • Bacterial sepsis (Streptococcus species, E. coli, Salmonella species, etc.)
  • Feline infectious peritonitis
  • Feline leukemia virus
Gastrointestinal infections
  • Feline parvovirus
  • Salmonella species
  • Giardia lamblia
  • Campylobacter species
  • Isospora species
  • Feline coronavirus
Respiratory tract infections
  • Feline calicivirus
  • Feline herpesvirus
  • Bordetella bronchiseptica
  • Chlamydophila felis
  • Mycoplasma species

Many of these infections can cause death if left untreated. Symptoms can vary, but veterinary assistance should always be sought if any kitten is showing the symptoms associated with fading kittens. Your vet may want to run specific tests to see if any of these infections are involved.

divider single cat paw oct 2024

Conclusion

Kittens are incredibly delicate, especially in the first few weeks of life. Sometimes there is nothing that can be done for certain kittens, but vigilance from owners can certainly help catch a few causes of kitten death that can be prevented.

As kittens start to be weaned, they’re usually out of the “danger zone”, and you can look forward to watching those little bundles of fluff grow into active and healthy cats.


Featured Image Credit: Rembolle, Shutterstock

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything cat

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.




How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Catster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.


Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

Ask Dr. Paola – Help! My Cat Suddenly Has Dandruff! (March 30, 2026)

Welcome to our “Ask Dr. Paola” series, where every Monday we bring expert advice straight from Dr. Paola Cuevas (MVZ) to help our...

Your Cat Keeps Vomiting After Eating: Here’s What’s Going On

Cats vomit. It’s one of the less glamorous facts of life with a feline, and most cat owners have cleaned up more than...

Ask Dr. Paola – Help! My Cat Gets Diarrhea from Wet Food! (March 23, 2026)

Welcome to our “Ask Dr. Paola” series, where every Monday we bring expert advice straight from Dr. Paola Cuevas (MVZ) to help our...

Cat Shampoo Alternatives That Are Already in Your House

If your cat has ever gotten into something disgusting and you’ve found yourself without cat shampoo, we’re here to help. Before you panic...

More related

Olga and the Vacuum: How I Helped Her Cope

Hi, I’m Christopher! Read my introduction to learn more about me and my silly Russian Blue cat, Olga. Although she can tolerate thunderstorms...

What Can Kill a Cat? 16 At-Home Items Vets Tell Us To Watch Out For

Being a cat parent is a responsibility that should be taken seriously. Your cat needs water, food, frequent litter changes, grooming, playtime, and...

Cat Has Bite and Scratch Wounds? Our Vet Answer What to Do

Cats are territorial creatures, and when roaming the suburbs, they often feel the need to challenge another feline that dares invade their space....

Why Does My Cat Have Diarrhea? 8 Vet-Reviewed Reasons

Cat owners know how aloof their feline companions can be, and we can sometimes miss signs telling us that something is off, so...

Keep reading

Can Cats Eat Rice Pudding? Vet Reviewed Nutrition Facts & FAQ

Sometimes, it can be tempting to treat our cats to a little bit of something we are enjoying, but it can be tricky to tell which foods are good for them and which are not. If you are wondering whether...

Can Cats Eat Rice Pudding

How to Calm an Angry Cat: 7 Vet-Approved Steps & Tips

Cats can experience a wide range of emotions, anger included. Although they might not experience anger the same way we do, there’s no doubt that felines can get angry from time to time. Anger is not an ideal experience for...

owner petting a hissing angry tabby cat

Are All White Cats With Blue Eyes Deaf? Vet-Reviewed Facts & FAQ

At some point, you’ve likely heard someone say that all white cats are deaf—particularly those with blue eyes. But is this factual? Not entirely! While white cats with blue eyes certainly are more prone to hereditary deafness—white cats, in general,...

turkish cat with blue eyes_love pattern_shutterstock

Why Is My Cat So Hungry All of a Sudden? 6 Vet-Reviewed Reasons

Most domestic cats like to eat small, frequent meals daily instead of one or two feasts. It might be normal to see your cat returning to their food bowl several times throughout the day, especially if they’re only snacking. However,...

maine coon cat eating

Are Burmese Cats Hypoallergenic? What You Need To Know!

Since they’re affectionate, playful, and fiercely loyal, the Burmese cat is very easy to love. If you’re an allergy sufferer but would love to share your life with one of these wonderful cats, you’ll be pleased to learn that the...

Closeup Burmese Cat Stands on Gray background

Disaster Preparedness for Cats: 12 Vet-Approved Steps to Take

No one likes to think it could happen to them. After all, we have cell phones and technology that can alert us to potential disasters well before they strike. Yet, many dismiss the power and destruction of these catastrophic events,...

cat walking next to its owner

How to Retrain a Cat to Use a Litter Box: 13 Vet-Approved Tips

Inappropriate elimination can be difficult to deal with, resulting in ruined belongings and strained relations between cats and their favorite people. It’s one of the most commonly reported behavioral problems in cats. Litter box issues are often caused by stress,...

Ginger cat in blue litter box

Can Cats Eat Meatloaf? Vet-Reviewed Diet Facts & FAQ

Whenever you sit down to eat, you can be sure you’ll have the full attention of your cat. While we might know better than to share all our food with them, our kitty’s twitching nose and unrelenting stare can make...

Can Cats Eat Meatloaf

Love Cats? So Do We! Join the Catster Community

Stay informed with expert pet care insights delivered straight to your inbox! Discover professional guidance on animal behavior, feeding tips, trusted product picks, and much more.




Sign up for the Catster Email Newsletter

Stay informed with expert pet care insights delivered straight to your inbox! Discover professional guidance on animal behavior, feeding tips, trusted product picks, and much more.