Get

In Your Inbox

Catster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

5 Most Common Cancers in Cats (Vet Answer): Signs, Causes & Treatments

cat being observed by a female veterinarian

It’s an unfortunate reality that cats are susceptible to cancer, just like humans are. Advances in veterinary medicine and pet care are making it easier to detect cancer, though, and with the subsequent increase in lifespans, the rates of diagnoses are increasing.

However, diagnosis can still be difficult, especially since older animals often suffer from other diseases. In many cases, differentiating cancer from these underlying diseases poses a medical challenge and typically requires a diagnostic process of bloodwork, ultrasounds, X-rays, and biopsies. So, what are the five most common cancers found in cats, and how serious are they?

divider 3 paws

The 5 Most Common Types of Cancers in Cats

1. Lymphoma

Lymphoma is cancer of the “lymphatic system,” a system of lymph nodes, ducts, and connecting vessels that run throughout the entire body. It is a vital component of the immune system in fighting disease. Since the lymphatic system is spread throughout many organs, lymphoma can be found in many different parts of the body, such as the chest, lymph nodes, and abdomen.

Although cats can be affected by lymphoma at any age, most animals tend to be diagnosed in their mid-life, between 10 and 12 years old. Due to its association with feline leukemia virus (FeLV), and feline immunodeficiency virus (FIV), it is most common in unvaccinated and unneutered outdoor male cats. However, control of these viruses with increased testing and vaccination is helping the incidence of certain types of lymphoma caused by the spread of these viruses.

Certain forms of lymphoma can be treated, and treatment can offer reasonably good survival times, between 2 and 4 years. It normally entails chemotherapy via a veterinary specialist oncologist. Depending on the type of lymphoma that is present, chemotherapy will be weekly infusions or daily tablets given to your cat by you at home. This can achieve a good remission rate of between 50% and 80%. Ensuring that your cat is vaccinated against FeLV and ensuring that they have no contact with FeLV- and FIV-infected cats will help with the prevention of lymphoma, though it does not eradicate the risk in its entirety.

Sick cat in animal hospital
Image Credit: Kachalkina Veronika, Shutterstock

2. Squamous Cell Carcinoma

Squamous cell carcinoma (SCC) is second to lymphoma as the most common tumor found in cats. During checkups, you may notice your veterinarian look into the mouth of your cat and rub their hands over their heads and ears. While this may look like a head massage, they are checking for signs of any tiny scabs that are typical of SCC. Cats that are particularly light in pigment are prone to SCC growth on their ears, temples, and nose, caused by exposure to ultraviolet light (i.e., the sun). Treatment often involves amputation of the ears, so it is helpful to prevent this type of cancer by applying cat-friendly sunscreen and zinc, particularly in hot countries where UV exposure is high.

SCC tumors are also common in the oral cavity. They are particularly invasive and aggressive, spreading quickly to other parts of the body, such as the lymph nodes and chest. They also aren’t often caught early due to their location; it often isn’t until the cat is eating poorly or has bad breath that their owner notices something is wrong, contributing to a poorer prognosis. Treatment is difficult because oral surgery is complicated, and it can often be impossible to remove a mass from the mouth without resorting to things like jaw amputation. Additionally, SCC is typically not that responsive to chemotherapy.


3. Mammary Cancer

Mammary cancer is common in cats, and unfortunately, 80–96% of the tumors are malignant. Unlike humans, cats have eight mammary glands existing in two “chains” of four glands each, running parallel to one another. This means a tumor can start as a tiny nodule and spread through the gland, then the chain, and throughout the body.

To reduce the chances of mammary cancer, get your cat spayed before their first heat cycle, around 6 months of age. Spayed cats have a 91% less chance of developing mammary cancer, so it is an excellent preventative measure. In female cats older than 10 years, mammary cancer is the most common type currently diagnosed. If your cat will allow it, routinely examine your cat’s belly to check for any lumps and bumps (treat it like a nice massage). Due to this cancer’s aggressive nature, early intervention is key. Treatment normally involves surgery (removing the tumor or doing a complete “mammary strip” and taking out the entire chain of mammary tissue) or a combination of surgery and chemotherapy if the disease is at an advanced stage.

Closeup veterinarian is making a check up of a adult maine coon cat with stethoscope in vet clinic
Image Credit: Ermolaev Alexander, Shutterstock

4. Fibrosarcoma

Fibrosarcomas are aggressive tumors in cats that typically present as lumps underneath the skin. While they can arise at any location in the body, they tend to develop in between the shoulder blades, and there may be a link between vaccinations and the development of fibrosarcoma at the injection site. Therefore, vets often vaccinate cats on alternating sides of the body, sometimes in the limbs, rather than injecting them in the scruff of the shoulders every time. Treatment normally involves a combination of surgery, radiation, and chemotherapy. Surgery can be curative if the tumor is small and found before it has spread.

It is normal for a cat to lump the injection site for up to 6 weeks after they’ve had their vaccinations. This is simply inflammatory and normally resolves on its own. However, if it doesn’t disappear or gets larger, get it checked out by your veterinarian.


5. Mast Cell Tumors

Mast cell tumors can be found in the spleen, the skin, or the intestines. On the skin, this tumor will present with a lump that is often small, raised, and itchy. The good news is that unlike in dogs, mast cell tumors of the skin in cats are often benign, meaning they won’t spread to other parts of the body and are curative with surgical removal.

However, mast cell tumors found internally are more aggressive and often spread to other organs in the body. Cats will show signs of being unwell, including weight loss, vomiting, diarrhea, blood in stools, and loss of appetite. Treatment is more complicated and compared to cats with the cutaneous form of the tumor, tend to have a poorer prognosis.

divider 3 paws

Conclusion

Cancer is never a nice word to hear in any context, but the more information you are armed with, the better you can prepare yourself for the decisions you may need to make about your cat. If you have any worries about your pet, it is always best to get them checked by your veterinarian. Early detection and intervention are essential for improving treatment outcomes, which is why veterinarians promote annual health checks at vaccination time.

Cats are good at hiding signs of illness from their owners until their bodies can no longer handle it, so you must act as your cat’s advocate if they are showing signs of being unwell or have a particular lump or bump that you are worried about.

See also:


Featured Image Credit: David Herraez Calzada, Shutterstock

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything cat

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.

How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Catster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

2 Responses

  1. Our cat Josephine has just gone into the vets today to have two long tumours removed outside her abdomen! They said they will need to also do tests On the tumours! What are the chances of tumours returning? She is 9 years old!????????????

    1. Hi Esther john, it depends on the nature of the tumors and the case, have a chat with your vet and if you wish for a second opinion then you can ask a vet at www.pangovet.com. We wish Josephine good health.

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.

Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

When Is Pet Cancer Awareness Month? History & How to Celebrate

It is many pet parents’ worst nightmare to receive the devastating news that their beloved pet has cancer. This unfortunate disease can affect...

Can Cats Eat Black Pepper? Vet-Approved Precautions & Alternatives

People have been peppering their dishes for over 4,000 years since black pepper was first used in India. Since its discovery, it’s only...

Why Does My Cat Hit Me With Her Tail? 5 Vet Approved Reasons

If you have ever wondered why your cat likes to hit you with her tail, that’s precisely the question we will answer in...

White Scottish Fold Cat: Info, Pictures, Facts & History

The White Scottish Fold is a unique breed that is popular for their distinctive and charming physical traits. Most have folded ears, rounded...

More related

7 Shorthair Cat Colors for British, Exotic & Oriental Breeds (With Info & Pictures)

One of the most unique things about shorthair cat breeds is the diverse range of colors and coat patterns they’re available in. While...

Oriental Longhair Cat Breed: Info, Pictures, Temperament & More

You might be smitten by the majestic look of the elvish Oriental Longhair. If they caught your eye, you probably want to learn...

Can Cats Eat Paprika? Vet-Reviewed Facts & FAQ

Paprika is a commonly used spice that is made from dried peppers. The peppers used in paprika can be sweet or spicy peppers...

7 Pet Friendly Hotels in Savannah, GA (2025 Update)

Coastal tranquility meets rich Southern culture in Savannah. Here, modern dining and entertainment mix seamlessly against the backdrop of historic architecture and live...

Keep reading

Why Does My Cat Meow When I Sneeze? Vet-Reviewed Facts & Funny Videos

Most cats are devoted to their humans; they commonly hang out and spend lots of time with their favorite people. Some cats meow in response to their owners’ sneezes; if yours does, it may have led you to wonder, “Why...

Young Asian woman sneezing which suffering from first symptoms of cat's fur allergy

Why is My Cat Throwing Up Yellow Liquid? 5 Vet Approved Reasons

Your cat vomiting can be concerning, but it may alarm you when they throw up yellow liquid. This colorful concoction surely could not be good, right? While yellow vomit looks incredibly unnatural, all it means is that it is mostly...

tabby white british shorthair cat vomit outdoors

Is Neem Oil Poisonous to Cats? What You Need to Know! Vet-Verified Facts

Neem oil is the current trending natural remedy of the month, being touted for everything from insect repellent to treatment for ringworm. Anecdotes of its use on pets have been reported, but vets are not so quick to jump on...

neem oil with mortar and pestle

My Cat Drank Christmas Tree Water! What Should I Do? Vet Approved Advice

A real tree at Christmas time recalls memories of past holidays. Perhaps you even went to cut one down or remember decorating one when you were young. However, while they bring us warmth and joy during Christmas, a real tree...

tabby cat sitting behind the christmas tree

How Do I Calm a Feral Cat? 5 Steps That Can Help

Have you ever interacted with a feral cat? “Interacted with” might not be the right wording, as feral cats will often not let you get close to them, let alone let you touch them. In fact, a feral cat might...

two feral cats

Can Cats Eat Eggplant? Vet-Reviewed Nutrition Facts

We all love sharing food with our cats but often wonder what foods are fine or harmful. Eggplant might be one of those foods you are unsure about. Even though you might be tempted to share some eggplant with your...

Can Cats Eat Eggplant

Why Do Cats Like to Be Pet While Eating? 6 Vet-Reviewed Reasons

Cats may have behaviors that are almost “expected” of them, but mealtimes can bring out unusual habits. Some cats love to eat alone, some prefer eating from a raised position, and others want the company of their owners when they...

Two cats being fed cat food from a tin can

Why Is My Cat Missing the Litter Box? 11 Vet Reviewed Reasons & Advice

If your feline is missing the litter box, it can quickly become very annoying. You’ll have to clean around the litter box as well as clean out the litter box. It may even seem like your cat is missing the...

maine coone in litter box