Get

In Your Inbox

Catster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

Is Cat Pee Toxic or Can It Make You Sick? Vet Verified Health Facts & FAQ

Share

man cleaning cat litter tray

Before bringing a cat into your home, there are several factors to consider. Not only should you be confident that you can care for a cat, but you should also be assured that a cat is the right fit for you. If you have allergies, a cat may not be right for you.

With this in mind, there are other health concerns to consider. For instance, can cat pee make you sick? Is cat pee toxic? While cat urine may make a person sick, it isn’t likely. Cat urine contains ammonia, and in large quantities, a person may become unwell when exposed to it. It can also contain bacteria and allergens, which can be harmful to people.

So, how do you know if you’re being affected by your cat’s urine? How can you prevent that from happening? Below, we’ll discuss ammonia exposure from cat urine, as well as allergies and infection risks.

divider 3 paws

What Is Ammonia?

Ammonia is a colorless gas, it is a corrosive nitrogen and hydrogen compound with a sharp odor. If enough ammonia comes into contact with your eyes, throat, or lungs, you can experience serious issues.

ammonia
Image Credit: luchschenF, Shutterstock

How Can You Be Exposed to Ammonia?

While there is ammonia in cat urine, there typically isn’t enough to bother a healthy person. Humans and other animals also release ammonia in their urine, so it isn’t a feature unique to cats. People who live on or near farms or sewage treatment plants may see higher ammonia levels in their environment due to the greater amount of animal or human urine in their area.

Ammonia is used in many products, including household cleaners, fertilizers, fuels, and refrigeration units. Basically, there are plenty of ways to be exposed to ammonia, and few of them involve your cat.

However, it’s not impossible. If your cat’s litter box is not cleaned well and their urine accumulates, ammonia gas can increase.

Avoiding Exposure to Ammonia

Possible ammonia exposures exist all around you. How do you avoid them?

First, you should never mix household cleaners. A mixture of household cleaners can rapidly release dangerous amounts of ammonia gas. If household cleaners are accidentally mixed, do not try to clean them or dispose of them. Instead, leave the room, shut the door, evacuate all humans and pets from the home, and call emergency services.

Another way to avoid dangerous levels of ammonia is to keep all ammonia-based products away from children or pets. If the items are insecurely stored, they can be easily spilled and may create hazardous amounts of gas.

To avoid ammonia exposure from your cat, clean the litter box daily. Thoroughly clean it to ensure that all clumps of urine are removed. You should also dump and replace your cat’s litter and clean the litter box regularly.

divider 3 paws

What Are the Side Effects of Breathing Cat Urine Ammonia?

The normal amounts of ammonia in your cat’s urine typically won’t bother a healthy person. The Centers for Disease Control and Prevention (CDC)  states that no health effects have been found in humans exposed to typical environmental concentrations of ammonia. People with asthma or other respiratory conditions may be more sensitive. If you are prone to breathing issues and your cat’s urine bothers you, consult with your doctor.

Exposure to high levels of ammonia can be irritating to the eyes, throat, lungs and skin. In severe cases, a person can suffer from lung damage and even death, but it usually only happens after prolonged exposure to extremely high levels of ammonia. Your cat cannot produce that much ammonia, even if the litter box is not well-maintained.

woman cleaning her pet cat's litter box
Image Credit: sandyman, Shutterstock

Allergies

For people with cat allergies, the protein Fel d 1 protein is the main allergen that causes the allergic reaction. Fel d 1 is mostly found in the saliva and skin (sebaceous glands) of cats. It is spread throughout their hair and skin during grooming, and then dispersed on dander and shed hair around the home. Fel d 1 can also be present in cat urine. So although it is not usually a significant concern, it is a potential source of allergens for people with cat allergies.

Infection risk

Cat feces generally pose more of an infection risk to humans than urine, but cat pee may be contaminated by feces in the litter box and may itself contain harmful bacteria. For example the bacteria Escherichia coli can be a cause of feline urinary tract infections, humans can also suffer from infections from this bacteria.

Leptospirosis is also a zoonotic disease, meaning that it can also be transmitted to humans. The bacteria that cause it are spread in the urine of infected animals. Research on leptospirosis in cats is limited and, although rare, it has been demonstrated that cats can be susceptible to infection.

divider 3 paws

How to Prevent Your Cat’s Urine from Affecting Your Health

Your cat’s urine shouldn’t affect your health as long as their litter box is cleaned and changed regularly. Without a significant accumulation of urine, there isn’t a chance for high ammonia levels to develop.

How often you need to change the litter and thoroughly clean the litter box will depend on how many cats you have, the type of litter and number of litter boxes, but you should scoop the litter box once or twice a day. Wear gloves when cleaning the litter box, especially if pregnant or immunocompromised (or ideally get someone else to do the job). Thoroughly wash your hands afterwards.

If your cat has an accident outside of their litter box, clean it promptly and properly. Cleaning the spot with an enzyme-based cleaner can effectively break down the odor. If the area isn’t cleaned well, your cat may return to it later and pee again, adding to the urine buildup. When cleaning up an accident, avoid using ammonia-based cleaners. The cleaners can encourage your cat to return and urinate there again.

Cleaning up after our pets is not the most enjoyable part of owning them. Despite keeping a clean litterbox, cat odors and stains may still exist around the house. Sometimes, even the best litter box setup needs extra help. If you're tired of dealing with bad smells from litter boxes, Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray can help with the worst pet stains and smells. Additionally, the Advanced Bio-Enzyme Cat Litter Deodorizer neutralizes odors upon contact.

Our Favorite Products

Image Product Details
Best Enzyme Cleaner Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray
  • Works on multiple surfaces
  • Gentle yet effective
  • Lifts stains & set-in odors
  • Best Litter Additive Advanced Bio-Enzyme Cat Litter Deodorizer Advanced Bio-Enzyme Cat Litter Deodorizer
  • Neutralizes odor within cat litter
  • Cat-safe
  • Unscented
  • At Catster, we’ve admired Hepper for many years and decided to take a controlling ownership interest so that we could benefit from the outstanding designs of this cool cat company!

    If you feel that your health is still being affected despite good litter box cleaning habits, talk to your doctor and your vet. It could be a sign that you or your cat are experiencing a medical issue.

    divider 3 paws

    Final Thoughts

    Is cat urine toxic? Cat urine can irritate your eyes and respiratory system if high levels of ammonia have built up, but it usually isn’t an issue for households with well-maintained litter boxes. Cat owners with allergies or other health issues may be more sensitive to cat urine and should minimize their exposure by asking someone else to clean the litter box. If your cat’s urine suddenly produces a stronger odor, make an appointment with your vet to determine whether they’re suffering from a health condition.


    Featured Image Credit: New Africa, Shutterstock

    Want content like this delivered to you?

    Sign Up For Our Newsletter

    News, insights, expert advice, and everything cat

    * By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.




    How useful was this post?

    Click on a star to rate (you can leave written feedback after clicking submit)

    Help us improve Catster for pet parents!

    Your feedback really matters.

    What did you like about this post? Also how can we improve it?

    Join the conversation

    Leave a Reply

    You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.


    Catster's Digital Magazine is Back!

    Vet-approved health & behavior advice

    Real cat stories & community features

    The Surprisingly Simple Ways to Help a Cat With Hairballs

    Cats spend an astonishing amount of time grooming. It is part hygiene routine, part comfort ritual, and part instinct that traces back generations....

    What a CATastrophe! A Tire-ing Ordeal For a Pony in the UK

    As you would expect, our weekly news updates are usually centered around feline topics – we are a cat care website after all...

    Ask Dr. Paola – Help! My Cat Has Stopped Eat His Wet Food! (June 1, 2026)

    Welcome to our “Ask Dr. Paola” series, where every Monday we bring expert advice straight from Dr. Paola Cuevas (MVZ) to help our...

    Chatting About Fake News in the Pet World, AI Again, and New Age Journalism | Chatty Cattys, Episode 23

    Navigating the modern digital landscape requires a sharp eye to distinguish fact from fiction. In this episode of Catster’s podcast, Chatty Cattys, Nicole...

    More related

    Why Is My Cat’s Tail So Long? Our Vet Explains Tail Genetics, Function & FAQ

    If you’ve ever looked at your cat’s tail and wondered why it’s as long as it is, you’re not alone. Cat tails are...

    25 Best Gifts for Cat Lovers in 2026: Thoughtful, Unique & Out-of-the-Box Ideas

    Sometimes finding the perfect gift for your cat-obsessed friends can be tricky, but we’ve curated a list of the purr-fect ideas. Any pet...

    Why Does My Cat Sit and Sleep on My Desk? 8 Possible Reasons

    Cats are interesting animals, which is one reason why they’re enjoyed as household companions by humans from all walks of life throughout the...

    How to Throw a Cat Birthday Party for Your Kitty

    It’s time to break out the party hats! Your cat is turning a year older, so what better cause to celebrate? You may...

    Keep reading

    Should I Get a Kitten for My Cat? Vet-Approved Introduction Tips & FAQ

    Introducing pets is an equally exciting and scary prospect for devout cat owners. Will they love one another and enrich each other’s lives in your absence? Or will they jockey for power and aggressively protect their territory, making life a...

    cat-smelling-kitten

    Can Cats Eat Arugula? Vet-Verified Nutrition Facts & FAQ

    Arugula is a bitter and slightly spicy plant that we often put in salads. With its increasing popularity in health food recipes, it is common to wonder if it is safe and healthy to serve to your cat. So can...

    Can Cats Eat Arugula

    Why Does My Cat Kick Litter Out of the Box? 5 Vet-Reviewed Reasons

    Cat owners all over the world are familiar with that awful feeling of stepping barefoot on small litter pebbles, which is usually followed by an explosive, “Why?!” Cats kicking litter out of their box is a behavior that flummoxes many...

    orange cat beside litter box

    How to Tell If You’re Allergic to Cats: 7 Signs to Look For

    As pet parents, we adore our feline friends, and owning a cat is a truly wonderful experience. Even though cats can be aloof, moody, and have a habit of doing whatever they please, they can also be loving, cuddly, sweet,...

    girl sneezing near cat

    Meow Mix Cat Food Review of 2026: Recalls, Pros & Cons

    Review Summary Meow Mix is one of the most popular cat food brands. It’s manufactured in Alabama and Thailand, and cats all over the world love it. As their jingle states, cats ask for it by name. Because of its...

    Meow Mix Cat Food Review

    Why Do Cats Like Clean Laundry? 4 Vet-Reviewed Reasons

    For some reason, cats can’t seem to resist clean laundry. Most relish burrowing into warm laundry fresh from the dryer, and many refuse to move once comfortably snuggled deep in a laundry basket full of toasty sheets or clothes. But...

    Cute kitten sleeping in laundry basket

    Pheromone Diffuser for Cats: Vet-Reviewed Pros, Cons & FAQ

    Pet parents use pheromone diffusers to reduce stress and anxiety in cats. They release continuous streams of synthetic pheromones that can decrease anxiety and are frequently suggested as ways to manage unwanted stress-related behavior, such as marking and scratching. Cats...

    Synthetic Pheromene Diffuser and Tabby Cat

    Can Cats Eat Imitation Crab? Vet-Approved Facts & FAQ

    You’ve most likely seen an old cartoon where someone tosses a bit of seafood out to a cat. Typically, this seafood is a fish, but if you’re a cat owner, you know the smell of any seafood can attract your...

    Can Cats Eat Imitation Crab

    Love Cats? So Do We! Join the Catster Community

    Stay informed with expert pet care insights delivered straight to your inbox! Discover professional guidance on animal behavior, feeding tips, trusted product picks, and much more.




    Sign up for the Catster Email Newsletter

    Stay informed with expert pet care insights delivered straight to your inbox! Discover professional guidance on animal behavior, feeding tips, trusted product picks, and much more.