Get

In Your Inbox

Catster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

Is Lidocaine Safe For Cats? Our Vet Discusses Safety & Risks

Catster_Is Lidocaine Safe for Cats

Even though cats typically aren’t as vocal or outwardly expressive of their pain as canines, they do still experience pain, leading veterinarians to look for safe and effective pain management medications. One that you may be wondering about is lidocaine. Is it safe for cats? The answer is yes, only when it’s used at the proper dosage and route of administration by a veterinary professional, but it still may not be the best choice for your feline friend. Here’s what you need to know about lidocaine use in cats.

divider 1 paws

What Is Lidocaine?

Lidocaine, also known under the brand name Xylocaine, has many potential uses in veterinary medicine. It is a local anesthetic, meaning it blocks pain responses to an area without affecting consciousness. It is commonly used for minor surgeries, such as removing small growths, setting up nerve blocks or epidurals for pain management or surgery, or controlling local pain. It’s mainly used in combination with other pain killers, sedatives, or general anesthetics.

Lidocaine also affects the heart and can be used to treat certain arrhythmias or abnormal heart rhythms, although it’s rarely used in cats for this purpose.1 In felines, it is typically used to desensitize the larynx before inserting an endotracheal tube when they are undergoing general anesthesia.

Even though lidocaine is useful for many uses in animals, it needs to be used with caution in cats because they seem to be more sensitive to it, with reported variable toxic doses depending on the route of administration.

a woman using EMLA (Lidocaine + Prilocaine) A topical anesthetic cream used to numb the skin

Image By: luchschenF, Shutterstock

How Is Lidocaine Given?

You’ll likely not run across lidocaine except perhaps in human topical ointments or sprays. Remember, don’t use any human medications on your cat without a veterinary prescription. Instead, any interactions with lidocaine will likely be when it is used on your cat by your veterinarian in the clinic.

Lidocaine can be injected into the skin to desensitize a painful area or one that needs to be worked on, such as suturing up a wound or taking a biopsy. It may also be injected around nerves to prevent pain, which can be used in diagnostics and surgeries. It may be used in epidurals to decrease the amount of general anesthesia needed for certain surgeries and may be sprayed down a cat’s throat before intubating them for surgery.

For animals with heart arrhythmias, lidocaine may be given intravenously to help regulate those rhythms, or it may be applied on the skin via an ointment, spray, or patch to help control pain.

While lidocaine has been proven to be extremely useful, it can also be toxic to cats at fairly low doses, so your vet will use it with caution or choose a different medication instead.

Potential Side Effects of Lidocaine in Cats

A cat’s body doesn’t handle lidocaine the same way that a dog’s does. Instead, they start to exhibit signs related to the central nervous system, even when used at low doses.

These may include:
  • Lethargy
  • Central nervous system depression
  • Incoordination
  • Nausea/vomiting
  • Breathing difficulties
  • Seizures
Less-noticeable signs include:
  • Low blood pressure
  • Cardiac effects

Keep in mind that most reactions are fairly mild when lidocaine is given as a local anesthetic or topically by a veterinary professional, but they can be worse if it’s given intravenously, especially in high amounts, or epidurally. That said, as long as your vet prescribes lidocaine at the proper dose for your cat, you likely won’t see any of these signs at home.

Veteterinarian explaining to woman cat medical condition
Image By: Nestor Rizhniak, Shutterstock

divider 3 paws

Frequently Asked Questions (FAQ)

Can I Use Lidocaine on My Cat?

Most applications of lidocaine will be done in a veterinary clinic rather than at home, but there may be times when your vet prescribes a lidocaine ointment, spray, or patch to help control your kitty’s pain. If this is the case, follow their directions specifically, and don’t use it otherwise unless directed by your veterinarian.

Never use a human ointment or cream containing lidocaine on your cat, and make sure your cat is not around you if you need to apply it yourself. Avoid your cat getting into contact with the spray or cream, or an area on your body where the cream has been applied, and don’t let them lick it off.

What Is Lidocaine Used For in Animals?

The most common use of lidocaine is as a local anesthetic for diagnostics or minor surgeries, including suturing wounds or biopsies. It may also be used to block specific nerves, such as for a tooth extraction. In felines, it may be used to desensitize the throat to ease intubation for general anesthesia, and it can be given intravenously to treat cardiac arrhythmias.

In cats, lidocaine must be used with caution, with vets needing to pay particular attention to doses when using it intravenously or epidurally.

How Can You Treat a Cat’s Pain at Home?

There may be times when your cat is in pain and you want to give them something at home to help them. However, you shouldn’t give your cat anything that hasn’t been prescribed to them for the specific condition that you are trying to treat. There are too many unsafe medications out there, and you may end up hurting your cat more.

Instead, consult your veterinarian to get a proper diagnosis and treatment for whatever it is that’s causing your cat pain. They may be able to recommend various types of pain management and get your cat to feel better safely.

If you need to speak with a vet but can't get to one, head over to PangoVet. It's an online service where you can talk to a vet online and get the advice you need for your pet — all at an affordable price!

PangoVet_Mention-in-Content for PangoVet2 save money

divider 2 cats

Conclusion

Lidocaine is considered safe for cats at the proper doses and for certain conditions by a veterinary professional or under their guidance. It is most commonly used as a local anesthetic for minor procedures or pain, or as a nerve block for things like extracting teeth. You likely won’t see it given intravenously for heart arrhythmias, like you might in dogs, or given epidurally for specific procedures. Your vet may prescribe topical lidocaine to help manage your cat’s pain in the form of ointments or a patch. Just be sure to follow the instructions and keep your cat from eating the product.


Featured Image Credit: luchschenF, Shutterstock

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything cat

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.


How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Catster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.


Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

Cat Coat Genetics: Vet-Approved Facts & FAQ

Have you ever wondered how your cat ended up with the coat color that they did? Maybe you know that your cat had...

Can a Cat Take Baby Aspirin? Vet-Approved Facts & Safety Tips

No one wants to think about their beloved pet in pain, so it can be tempting to give your cat some relief from...

8 DIY Catnip Toys You Can Make Today (With Pictures)

Suppose you want a new toy for your cat but can’t access the pet store. You can create various stunning DIY pet toys...

How to Discipline a Cat for Biting: 9 Tips & Tricks

Cats are sweet and cuddly-looking creatures, but that does not mean they cannot have their fair share of behavioral problems. One common behavioral...

More related

10 Best Halloween Cat Toys of 2026 – Reviews & Top Picks

Halloween can be a fun time of year, but we often overlook our kitties. While cats may not understand the concept of a...

Why Does My Kitten Bite Me? 5 Vet-Reviewed Reasons

Kittens always look cute but they do not always play cute. These rascally little animals love to roughhouse and explore the limits that...

Reintroducing Cats After the Vet: Feline Non-Recognition Aggression Explained

Feline non-recognition aggression is a phenomenon that occurs when one cat has been away from the house and, on their return, the home...

10 Best Cat Litters for Multiple Cats in 2026 – Reviews & Top Picks

Cats can be notoriously particular about their litter boxes. While some seem to be relatively mellow regarding litter consistency and scooping frequency, others...

Keep reading

How Often Will a Feral Cat Move Her Kittens? Vet Approved Facts & FAQ

You may have seen your domestic mama cat move her kittens more than once, and the same behavior is common for feral mother cats. Feral cats will move their kittens for various reasons. If the mother cat is unsatisfied with...

kittens in the grass with their mother

10 Best Lysine Supplements for Cats in 2026 – Reviews & Top Picks

Lysine is often used to treat symptoms commonly caused by feline herpesvirus infections. If your cat is diagnosed with this condition, your vet may prescribe or recommend a lysine supplement. If this is the case for your cat, there are...

cat having treat

My Cat’s Spay Incision Slightly Opened: Should I Worry? Vet-Verified Facts & FAQ

Spaying is a common practice for many pets. While complications are rare, it’s still important for cat owners to know how to respond to them in case something goes wrong. One of the most common complications is slight opening of...

sphynx cat after surgery

Cat Twitching: Vet-Verified Signs, Causes & When to See a Vet

Cats have many strange behaviors, like the peculiar chattering sound they make when seeing a bird or a laser pen. But when we see our cat twitching while awake, it’s natural to be concerned and look for the underlying reasons...

Cat scratching his ear while laying on a bed

How Do Cat Eyes Work? Vet-Reviewed Facts & FAQ

If you’re wondering why your cat has such an air of self-importance and superiority about them, it might be because their senses are so powerful and complex that they consider us mere humans simply inferior—and rightly so! Did you know...

Scared cat with wide eyes looking at you

6 Best Fresh Cat Food Delivery Services in Canada in 2026 – Reviews & Top Picks

Subscribing to a cat food delivery service is a fantastic idea for the modern pet parent. We’re so busy that sometimes finding the time or energy to go to the store for pet food can seem like the most inconvenient...

cat eating boiled eggs

Why Do Cats Hiss and Growl at Strangers? Vet-Reviewed Behavior Insights

Hissing and growling are ways cats communicate how they’re feeling. Hearing your cat hiss and growl can be shocking and a bit embarrassing if they’re doing it when you have house guests. Some cats may hiss and growl at strangers...

siamese cat hissing

How to Clicker Train a Cat: 4 Vet-Approved Steps

Most people will say that cats are untrainable, but the reality is that they can be trained if you take the right approach. Clicker training can be highly effective with young cats and kittens, giving you the tools to teach...

cat training