Get

In Your Inbox

Catster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

6 Health Risks of Keeping a Dirty Litter Box: Vet-Approved Sickness Signs

woman cleaning cat litter

Cleaning the litter box is one of the most laborious (not to mention smelly) tasks a cat owner must do every day, so it’s easy to let this job slide to the wayside. But did you know that slacking on your poop-scooping duties can have severe consequences for both you and your cat? It’s true, and it’s something you need to educate yourself on before you put off your litter box cleaning for another day.

Keep reading to find the most significant health risks that can occur due to a dirty litter box.

divider 3 paws

Top Tip for Cleaning & Combating Tough Litter Box Smells

Cleaning up after our pets is not the most enjoyable part of owning them. Despite keeping a clean litterbox, cat odors and stains may still exist around the house. Sometimes, even the best litter box setup needs extra help. If you're tired of dealing with bad smells from litter boxes, Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray can help with the worst pet stains and smells. Additionally, the Advanced Bio-Enzyme Cat Litter Deodorizer neutralizes odors upon contact.

Image Product Details
Best Enzyme Cleaner Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray
  • Works on multiple surfaces
  • Gentle yet effective
  • Lifts stains & set-in odors
  • Best Litter Additive Advanced Bio-Enzyme Cat Litter Deodorizer Advanced Bio-Enzyme Cat Litter Deodorizer
  • Neutralizes odor within cat litter
  • Cat-safe
  • Unscented
  • At Catster, we’ve admired Hepper for many years and decided to take a controlling ownership interest so that we could benefit from the outstanding designs of this cool cat company!

    divider 3 paws

    The 6 Health Risks of Keeping a Dirty Litter Box

    1. Urinary Tract Infections

    When you don’t scoop out your cat’s litter, your beloved kitty may squat directly over top of old urine or feces the next time that they go to eliminate. They may also step in these old excretions. The bacteria in their waste can then travel up your cat’s urethra, leading to a urinary tract infection (UTI). A dirty litter box can cause other health conditions due to the natural fastidiousness of cats; they simply do not want to enter a dirty litter box because it’s gross and makes them feel unclean. Examples of such conditions include Feline idiopathic cystitis (FIC) and feline urethral obstructions (FUO).

    Feline bladder stones often form as a result of UTIs and, therefore, are often linked to dirty litter boxes. These stones occur when organic materials accumulate in your cat’s bladder, blocking the urethra and making it difficult and painful for your cat to pee.

    Signs of a UTI in cats include:

    • Frequently attempting to urinate
    • Only passing small amounts of urine
    • Having bloody urine
    • Straining to pee
    • Crying while peeing
    • Not urinating at all
    • Urinating outside of the litter box
    • Licking of the perineal area
    IMPORTANT

    Please note that if your cat struggles to urinate and cannot pass any urine, you should immediately take them to an emergency vet, as the inability to pass urine is life-threatening if not promptly treated.


    2. Cat Scratch Disease (CSD)

    CSD is a bacterial infection that humans can get from dirty cat litter. It is caused by the Bartonella henselae bacteria and is most often passed to humans via cat bites or scratches; however, CSD can also occur from direct contact with dirty litter boxes.

    According to data from the Centers for Disease Control and Prevention, CSD is most common in children under 9 and individuals with weakened immune systems. Those with compromised immune systems are more likely to experience complications from CSD, such as eye infections that can lead to blindness and bacillary angiomatosis, an illness characterized by skin lesions.

    Signs of CSD include:

    • Swollen lymph nodes
    • Headache
    • Fever
    • Poor appetite
    • Fatigue
    persian cat checked by vets
    Image By: Beach Creatives, Shutterstock

    3. Salmonellosis

    Like CSD, Salmonella first infects your kitty before spreading to you. Your pet may be asymptomatic, so you might not even know they have the infection.

    Signs of salmonellosis include:

    • Diarrhea
    • Abdominal cramping
    • Abdominal pain
    • Fever

    Since Salmonella lives in the intestinal tract of animals, it is easy to see how it could be transmitted to you via your cat’s dirty litter. Although Salmonella can be considered normal flora for some cats, certain strains can cause issues in people.

    If you need to speak with a vet but can't get to one, head over to PangoVet. It's an online service where you can talk to a vet online and get the advice you need for your pet — all at an affordable price!

    PangoVet_Mention-in-Content for PangoVet2 save money


    4. Overexposure to Ammonia

    Your cat’s urine is full of ammonia, which is part of the reason it smells so bad. Cat urine is highly concentrated, so it has a strong odor, leading to eye, nose, and throat irritation and headaches. Long-term ammonia exposure can cause lung irritation, coughing, bronchitis, or pneumonia.

    As with CSD, children and individuals with weakened immune systems are more at risk.


    5. Roundworms

    Your cat’s excrement may be home to several types of parasites. Roundworms can pass from your cat’s feces onto you, causing a host of unfortunate side effects such as diarrhea, nausea, and coughing.

    If you believe your kitty has roundworms, visiting the vet is in order. Left untreated, severe infestations of this parasite can cause life-threatening consequences.

    cat on the table being checked by a vet
    Image Credit: brodtcast, Shutterstock

    6. Toxoplasmosis

    Toxoplasmosis is a disease caused by the Toxoplasma gondii parasite. It’s relatively common and is generally mild in cats, but because of its zoonotic potential, all cat owners need to be aware of its health implications.

    Signs of toxoplasmosis in humans include:

    • Muscle aches
    • Fatigue
    • Headaches
    • Swollen lymph nodes
    • Fever
    IMPORTANT

    People who are pregnant or have compromised immune systems risk developing serious complications from this disease. In addition, the infection can pass onto unborn babies, potentially leading to stillbirth, miscarriage, or severe health problems like seizures, jaundice, or eye infections.

    divider cat faces oct 2024Final Thoughts

    While no cat owner has ever looked forward to cleaning the litter box, it is a necessary evil that you must commit to doing daily. A clean box can not only prevent the above health conditions, but it will also stop your cat from eliminating outside of the box. The cleaner your cat’s litter box is, the happier and healthier you and your pet will be.


    Featured Image Credit: catinsyrup, Shutterstock

    Want content like this delivered to you?

    Sign Up For Our Newsletter

    News, insights, expert advice, and everything cat

    * By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.

    How useful was this post?

    Click on a star to rate (you can leave written feedback after clicking submit)

    Help us improve Catster for pet parents!

    Your feedback really matters.

    What did you like about this post? Also how can we improve it?

    Join the conversation

    Leave a Reply

    You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.

    Talk With A Vet Online

    Peace of mind,
    anywhere, anytime

    Affordable vet advice

    Working at Home With a Cat: Olga’s Pressure for an Early Dinner

    Hi, I’m Christopher! Read my introduction to learn more about me and my silly Russian Blue cat, Olga. Happy holidays, everyone! We are...

    Why Does My Cat Have a Fever? 5 Vet-Reviewed Common Causes

    Cats normally have temperatures between 100º F and 102.5º F; anything above that is considered to be a fever, also known as pyrexia....

    Sploot Veterinary Care | Heroes of The Pet World

    Veterinarians, vet technicians, practice managers, rescuers, behaviorists, nutritionists, trainers, volunteers, and other animal professionals are the backbone of pet ownership. Helping pets and...

    What Kind of Toys Do Blind Cats Like? 4 Vet-Reviewed Types & Suggestions

    If you find yourself the proud owner of a blind kitty, it can feel like there are a whole host of things that...

    More related

    What’s the Longest a Cat Has Ever Lived? Facts & Life Expectancy

    The longest a cat has been known to live is 38 years and 3 days. The oldest recorded cat is a tabby cat...

    How Do Cats Get Worms? Vet Reviewed Causes, Signs & Prevention

    Finding worms in your favorite feline’s poop or around their butt is never pleasant. But it is not uncommon for our pets to...

    Russian Blue Cat Breed: Info, Pictures, Temperament & More

    The Russian Blue cat is a striking feline with pale blue fur and distinctive emerald-colored eyes. They are known for their affectionate personality...

    Maine Coon Kittens for Sale in New York: Breeders List 2025

    Catster advocates for adopting before shopping, though we fully understand there are many reasons for seeking a breeder. So, we encourage it to...

    Keep reading

    9 Best Flea Treatments for Kittens (2025) – Reviews & Top Picks

    Bringing your fluffy new kitten home is an incredibly exciting time. However, you must ensure that the kitten doesn’t come with any unexpected visitors, like a load of fleas, for example! Choosing an effective and fast-acting flea treatment is essential...

    applying flea treatment to cat

    How to Get Your Kitten to Stop Biting: 6 Useful Tips

    Getting a new kitten in your life is always exciting. You can’t wait to cuddle and play with your new family member. Especially when they are young, cats are cheerful and playful animals, but sometimes they can get a little...

    kittten playing and biting owner's feet

    Can Cats Eat Hamburgers? Vet-Approved Feline Treats

    Cats are meat-eaters, and what is more carnivorous than a juicy burger made with ground beef, pork, chicken, or other meat? As long as the burger is properly cooked, is not processed, does not contain additional ingredients, like onion or...

    Can Cats Eat Hamburgers

    Can Cats Eat Yogurt? Vet-Reviewed Nutrition Facts & FAQ

    For many, thinking of cats brings up images of them lapping up a saucer of milk. While it’s safe for kittens to have their mother’s milk, older cats are lactose-intolerant, so giving them milk or yogurt could result in a...

    Can Cats Eat Yogurt

    8 Best Cat Foods for Kidney Disease in Canada of 2025: Reviews & Top Picks

    Learning that your cat has a chronic condition, such as chronic kidney disease (CKD), can feel scary. Though this condition is not curable or reversible, support and treatment can improve your kitty’s quality of life and help it live longer....

    top view of a cream maine coon cat eating dry and wet pet food from feeding dish

    Are Yucca Plants Toxic to Cats? Vet-Verified Ingestion Signs & Treatment

    Yucca, a kind of desert plant, is a popular garden plant that thrives in warm, dry areas. They don’t need a ton of water to grow, and they are distinctive and beautiful, with a big spray of spike-shaped leaves. They...

    Catster_Are Yucca Plants Toxic to Cats

    Do Cats Need Sunscreen When Going Outside? Vet-Approved Facts

    Applying sunscreen to a cat may sound a little messy or unnecessary, but some breeds and those with light-colored coats could benefit from wearing sunscreen at times. Cats that are at higher risk of skin damage due to sun exposure...

    cat on the beach

    Are Tapeworms in Cats Contagious? Vet-Reviewed Health Facts

    Testing for parasites and deworming are important aspects of pet care, especially in puppies and kittens. There is a relatively high likelihood that any dog or cat will become infested with some type of internal or external parasites, be they...

    tapeworm in a cat's stomach