Get

In Your Inbox

Catster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

Is Cat Pee Toxic or Can It Make You Sick? Vet Verified Health Facts & FAQ

man cleaning cat litter tray

Before bringing a cat into your home, there are several factors to consider. Not only should you be confident that you can care for a cat, but you should also be assured that a cat is the right fit for you. If you have allergies, a cat may not be right for you.

With this in mind, there are other health concerns to consider. For instance, can cat pee make you sick? Is cat pee toxic? While cat urine may make a person sick, it isn’t likely. Cat urine contains ammonia, and in large quantities, a person may become unwell when exposed to it. It can also contain bacteria and allergens, which can be harmful to people.

So, how do you know if you’re being affected by your cat’s urine? How can you prevent that from happening? Below, we’ll discuss ammonia exposure from cat urine, as well as allergies and infection risks.

divider 3 paws

What Is Ammonia?

Ammonia is a colorless gas, it is a corrosive nitrogen and hydrogen compound with a sharp odor. If enough ammonia comes into contact with your eyes, throat, or lungs, you can experience serious issues.

ammonia
Image Credit: luchschenF, Shutterstock

How Can You Be Exposed to Ammonia?

While there is ammonia in cat urine, there typically isn’t enough to bother a healthy person. Humans and other animals also release ammonia in their urine, so it isn’t a feature unique to cats. People who live on or near farms or sewage treatment plants may see higher ammonia levels in their environment due to the greater amount of animal or human urine in their area.

Ammonia is used in many products, including household cleaners, fertilizers, fuels, and refrigeration units. Basically, there are plenty of ways to be exposed to ammonia, and few of them involve your cat.

However, it’s not impossible. If your cat’s litter box is not cleaned well and their urine accumulates, ammonia gas can increase.

Avoiding Exposure to Ammonia

Possible ammonia exposures exist all around you. How do you avoid them?

First, you should never mix household cleaners. A mixture of household cleaners can rapidly release dangerous amounts of ammonia gas. If household cleaners are accidentally mixed, do not try to clean them or dispose of them. Instead, leave the room, shut the door, evacuate all humans and pets from the home, and call emergency services.

Another way to avoid dangerous levels of ammonia is to keep all ammonia-based products away from children or pets. If the items are insecurely stored, they can be easily spilled and may create hazardous amounts of gas.

To avoid ammonia exposure from your cat, clean the litter box daily. Thoroughly clean it to ensure that all clumps of urine are removed. You should also dump and replace your cat’s litter and clean the litter box regularly.

divider 3 paws

What Are the Side Effects of Breathing Cat Urine Ammonia?

The normal amounts of ammonia in your cat’s urine typically won’t bother a healthy person. The Centers for Disease Control and Prevention (CDC)  states that no health effects have been found in humans exposed to typical environmental concentrations of ammonia. People with asthma or other respiratory conditions may be more sensitive. If you are prone to breathing issues and your cat’s urine bothers you, consult with your doctor.

Exposure to high levels of ammonia can be irritating to the eyes, throat, lungs and skin. In severe cases, a person can suffer from lung damage and even death, but it usually only happens after prolonged exposure to extremely high levels of ammonia. Your cat cannot produce that much ammonia, even if the litter box is not well-maintained.

woman cleaning her pet cat's litter box
Image Credit: sandyman, Shutterstock

Allergies

For people with cat allergies, the protein Fel d 1 protein is the main allergen that causes the allergic reaction. Fel d 1 is mostly found in the saliva and skin (sebaceous glands) of cats. It is spread throughout their hair and skin during grooming, and then dispersed on dander and shed hair around the home. Fel d 1 can also be present in cat urine. So although it is not usually a significant concern, it is a potential source of allergens for people with cat allergies.

Infection risk

Cat feces generally pose more of an infection risk to humans than urine, but cat pee may be contaminated by feces in the litter box and may itself contain harmful bacteria. For example the bacteria Escherichia coli can be a cause of feline urinary tract infections, humans can also suffer from infections from this bacteria.

Leptospirosis is also a zoonotic disease, meaning that it can also be transmitted to humans. The bacteria that cause it are spread in the urine of infected animals. Research on leptospirosis in cats is limited and, although rare, it has been demonstrated that cats can be susceptible to infection.

divider 3 paws

How to Prevent Your Cat’s Urine from Affecting Your Health

Your cat’s urine shouldn’t affect your health as long as their litter box is cleaned and changed regularly. Without a significant accumulation of urine, there isn’t a chance for high ammonia levels to develop.

How often you need to change the litter and thoroughly clean the litter box will depend on how many cats you have, the type of litter and number of litter boxes, but you should scoop the litter box once or twice a day. Wear gloves when cleaning the litter box, especially if pregnant or immunocompromised (or ideally get someone else to do the job). Thoroughly wash your hands afterwards.

If your cat has an accident outside of their litter box, clean it promptly and properly. Cleaning the spot with an enzyme-based cleaner can effectively break down the odor. If the area isn’t cleaned well, your cat may return to it later and pee again, adding to the urine buildup. When cleaning up an accident, avoid using ammonia-based cleaners. The cleaners can encourage your cat to return and urinate there again.

Cleaning up after our pets is not the most enjoyable part of owning them. Despite keeping a clean litterbox, cat odors and stains may still exist around the house. Sometimes, even the best litter box setup needs extra help. If you're tired of dealing with bad smells from litter boxes, Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray can help with the worst pet stains and smells. Additionally, the Advanced Bio-Enzyme Cat Litter Deodorizer neutralizes odors upon contact.

Our Favorite Products

Image Product Details
Best Enzyme Cleaner Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray
  • Works on multiple surfaces
  • Gentle yet effective
  • Lifts stains & set-in odors
  • Best Litter Additive Advanced Bio-Enzyme Cat Litter Deodorizer Advanced Bio-Enzyme Cat Litter Deodorizer
  • Neutralizes odor within cat litter
  • Cat-safe
  • Unscented
  • At Catster, we’ve admired Hepper for many years and decided to take a controlling ownership interest so that we could benefit from the outstanding designs of this cool cat company!

    If you feel that your health is still being affected despite good litter box cleaning habits, talk to your doctor and your vet. It could be a sign that you or your cat are experiencing a medical issue.

    divider 3 paws

    Final Thoughts

    Is cat urine toxic? Cat urine can irritate your eyes and respiratory system if high levels of ammonia have built up, but it usually isn’t an issue for households with well-maintained litter boxes. Cat owners with allergies or other health issues may be more sensitive to cat urine and should minimize their exposure by asking someone else to clean the litter box. If your cat’s urine suddenly produces a stronger odor, make an appointment with your vet to determine whether they’re suffering from a health condition.


    Featured Image Credit: New Africa, Shutterstock

    How useful was this post?

    Click on a star to rate (you can leave written feedback after clicking submit)

    Help us improve Catster for pet parents!

    Your feedback really matters.

    What did you like about this post? Also how can we improve it?

    Join the conversation

    Leave a Reply

    You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.

    Talk With A Vet Online

    Peace of mind,
    anywhere, anytime

    Affordable vet advice

    Bengal Cat History: Exploring Their Origins and Variants

    Bengal cats are gorgeous domestic cats that look like they’ve just strolled out of the jungle. The International Cat Association (TICA) officially recognized...

    When Will My Current Cat Stop Hissing at My New Kitten? Vet-Verified Tips and FAQs

    Bringing a new pet home, especially a kitten, is exciting. The new addition to your family almost always brings joy to their new...

    My Cat’s Fur is Changing Color: 6 Vet Approved Reasons for Coat Changes

    Going gray as you age is a fact of life, and we either accept it or do something about it. Sometimes, we also...

    Can Cats Eat Centipedes? Vet-Verified Facts & Recommendations

    In the mind of a cat, it may be more exciting to chase after insects and other creepy crawlers than it is to...

    More related

    7 Favorite Cats From “Star Trek” & Beyond

    There have been more than 900 episodes of the 12 different iterations of Star Trek, including the animated series. There have also been...

    7 DIY Cat Toys for Kids They Can Make Today (With Pictures)

    If you have kitties at home, you know how they are always tearing up their toys. If you have kiddos at home who...

    3 Common Tortoiseshell Cat Health Problems & Care Tips

    A tortoiseshell cat isn’t a separate breed. Tortoiseshell is a color that can appear among quite a few cat breeds. This gorgeous pattern...

    How to Keep Litter Boxes from Smelling: 12 Vet Approved Tips

    A common goal among cat owners is keeping the litter box smell to a minimum. This can pose a bit of a challenge,...

    Keep reading

    Can Feral Cats Be Friendly? Vet-Reviewed Facts & Advice

    Feral cats aren’t socialized by humans, by definition. They haven’t been raised around humans and have spent much of their time with other cats instead. Therefore, feral cats typically act like wild animals and aren’t usually friendly—unlike the domestic cats...

    feral cat on the stairs

    Can Cats Eat Frosting? Vet-Reviewed Facts & FAQ

    Frosting is a delicious topping on cupcakes, cakes, and cookies. With its main ingredients of sugar, butter, and cream, it’s a sweet, tasty addition that is sure to make anyone want more. If you’re a cat parent, you’ve probably encountered...

    Can Cats Eat Frosting

    Why Does An Adult Cat Go Limp When You Grab Their Scruff? Vet-Verified Reasons & FAQ

    When mother cats want to move their kittens, they gently bite the skin on their necks to lift them. The kittens almost always react the same way: They go completely limp. There’s even a scientific name for this inert, lifeless...

    Owner grabbing a cat by the Scruff

    Signs of Aging in Cats: What Is Normal, What Is Disease? (Vet-Reviewed)

    The average cat lives for 13 to 17 years, but some can make it well into their 20s. Many of the changes their bodies go through as they age are normal, but there are also ones that can be signs...

    ginger-cat-on-owners-lap

    Will a Cat Only Purr for Humans? Do They Do it for Other Cats?

    You may have heard that cats only purr for humans. Well, how true is that? As adorable of a sentiment as it is, cats do not purr for humans exclusively. Cats have been observed purring for other cats and even...

    british shorthair cat yawning and purring

    Can Cats Eat Grasshoppers? Vet-Approved Nutrition Facts

    Have you ever seen your cat stalking a bug, like a grasshopper, only to gobble them down once they catch them? Could your cat get sick from eating grasshoppers? Cats can eat grasshoppers, but it is not a good idea...

    Can Cats Eat Grasshoppers

    10 Best Cat Foods for Indoor Cats in 2025 – Reviews & Top Picks

    If your cat lives indoors, then it’s sometimes worth considering buying them food that’s specifically designed for indoor cats. Their needs can vary considerably from their relatives that roam outside. Typically, indoor cats aren’t as active, so they can put...

    Indoor Cat Near Food Bowl

    Short Spine Syndrome in Cats: Vet-Reviewed Signs, Diagnosis & Treatment

    Short spine syndrome (SSS) is a rare, inherited condition that affects stump tail or tailless cats. You may not hear about this disease often, but this rare condition results in cats having an abnormally short spine, leading to a variety...

    Mekong Bobtail Male Cat