All About the Cat Brain — and Some Issues That Might Impact It

A hairless cat with blue eyes.
A hairless cat with blue eyes. Photography by Gareth Cowlin/Shutterstock.

How many times have you wondered what your cat was thinking? Perhaps understanding your feline’s mind starts with understanding the cat brain. (Or then again, maybe not.) Technically, the brain is the main organ that comprises the central nervous system of the cat. It is the control center for receiving and interpreting information that comes from the cat’s own body and from the outside world. Learning and perception takes place in the brain, and all of the sensations — sight, sound, smell, taste, touch and pain — are processed through here.

Anatomy of a cat brain

Cat brain chart.
Is this what your cat is thinking every day?

The brain is a lump of spongy pink nerve tissue located within the skull. It can be divided into three major parts: the cerebrum, the cerebellum and the brainstem.

The cerebrum makes up the majority of the brain tissue, and it has two major portions: the right cerebral hemisphere and the left cerebral hemisphere. The hemispheres are connected to each other by a piece of tissue called the corpus callosum, which allows messages to be transported from one side to the other.

The cerebellum can be found at the back of the brain, attached to the cerebrum. It’s responsible for physical coordination, balance and posture. Located at the base of the brain, the brainstem regulates important functions, such as blood pressure, breathing and heartbeat. Several membranes, called meninges, cover the brain. A fluid (called cerebrospinal fluid) is found beneath the meninges, bathing the brain and protecting it from injury.

Like any other organ, the brain may become diseased or disordered. The list of potential brain disorders is pretty long, but a few of the more common ones I encounter as a feline practitioner include seizures, cerebellar hypoplasia and brain tumors.

Cat seizures

Seizures occur when neurons in the brain begin to fire all at once, in an uncoordinated fashion. They are seen less commonly in cats compared to dogs. Seizures can be divided into primary seizure disorders and secondary seizure disorders.

Primary seizure disorders are those for which there is no underlying cause. This is better known as epilepsy. In dogs, there tends to be a genetic basis for epilepsy, but this doesn’t seem to be the case in cats.

Secondary seizure disorders are those for which there is a known cause. The list of disorders that can cause seizures in cats is extensive and includes infections (such as feline leukemia virus and toxoplasmosis), metabolic disorders (low blood sugar, low blood calcium, liver disease, thiamine deficiency), brain tumors, toxins (lead, antifreeze) and trauma. In most cases of secondary seizures, if the cause is addressed, the seizures will resolve. Cats with epilepsy may require anticonvulsant medication, depending on the frequency and severity of the seizures. The most commonly prescribed anticonvulsant is phenobarbital.

Cerebellar hypoplasia in cats

The cerebellum is responsible for coordination and fine motor skills in the cat. Cerebellar hypoplasia is a condition in which a kitten is born with an underdeveloped cerebellum at birth. The most common reason for this is an infection with the feline panleukopenia virus while the mother is pregnant. Affected kittens will have mobility issues as a result.

The severity of the condition varies from cat to cat, even among littermates. Some cats are mildly affected, while others really have difficulty getting from point A to point B. These cats may also have head tremors, sometimes called “intention tremors,” because they’re more pronounced when the cat is deliberately intending to do something with his head, like eat or drink.

Although cats with cerebellar hypoplasia may look like they’re struggling, these cats have no idea that they’re any different from other cats. Because they were born this way, they think they’re normal. The condition is not painful, and it is not progressive — it won’t get worse over time. There is no treatment for cerebellar hypoplasia, and there really is no need for one. What these cats lack in mobility, they make up in personality.

Brain tumors in cats

Sadly, just like any other organ, the brain is also susceptible to cancer. Brain tumors may be classified as primary or secondary. Primary brain tumors are those that arise from cells found within the brain or the membranes surrounding the brain. 0.1875 in

Secondary brain tumors are those that have metastasized (spread) to the brain as a result of a primary tumor elsewhere in the body. The clinical signs of a brain tumor can vary and include abnormal mental status or behavior such as stupor, head-pressing (the cat relentlessly presses its head against a wall or other surface), walking in circles or seizuring.

The three main treatment options for brain tumors are surgery, radiation and chemotherapy. Surgical removal of the tumor is rarely attempted, although meningiomas (tumors arising from the membranes that cover the brain) are sometimes surgically amenable. The goal of chemotherapy and/or radiation is to reduce the size of the tumor and control the symptoms. The prognosis for cats with brain tumors is poor.

So there you have all the brain basics. I’ve been a veterinarian for more than 28 years and, despite examining and treating thousands of cats, I’ve come to accept one thing for certain: I will never truly understand the feline brain. (I do enjoy trying, though.)

More potential cat brain disorders:

Here are some of the more common ones in cats:

  • seizures
  • cerebellar hypoplasia
  • brain tumors
  • infections
  • inflammations
  • hereditary disorders
  • metabolic disorders
  • toxic conditions
  • tumors
  • trauma

Thumbnail: Photography by Gareth Cowlin/Shutterstock.

Read more scientific facts about cats on

Dr. Arnold Plotnick is the founder of Manhattan Cat Specialists, a feline-exclusive veterinary practice on Manhattan’s Upper West Side. He is also an author of The Original Cat Fancy Cat Bible. Dr. Plotnick is a frequent contributor to feline publications and websites, including his own blog, Cat Man Do. He lives in New York City with his cats, Mittens and Glitter.

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