Get

In Your Inbox

Catster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

Feline Hyperesthesia Syndrome: Vet-Reviewed Signs, Treatment & FAQ

a woman's hands petting a cat

Feline hyperesthesia syndrome (FHS) is a condition in which a cat’s skin becomes ultra-sensitive1. It’s also known as twitchy cat disease and most often involves the fur and skin on a cat’s back, especially close to the tail. Cats with the syndrome often become agitated or aggressive when sensitive points are stimulated. Others chase their tails, or at the extreme end, they may urinate when parts of their bodies are touched. Anxiety and stress can make the condition worse.

There’s no cure for FHS, but with treatment, the signs can be well managed, and cats with the syndrome can live long happy lives.

divider cats oct 2024

What Is Feline Hyperesthesia Syndrome?

FHS isn’t a disease, but rather a cluster of clinical signs involving extreme skin sensitivity. Cats with the condition have skin that becomes hypersensitive, possibly to the point of pain. Two other common signs include uncontrollable muscle contractions and behavioral changes.

The lower back is a common trigger point. Cats with the syndrome often scratch or bite at the area after it has been stimulated. Some cats yowl or urinate when a sensitive spot is touched. Others act aggressively while being petted if an uncomfortable trigger point is touched.

There’s no known cure for the condition, but there are ways to manage some of the signs, including medication and behavior modification.

If you need to speak with a vet but can't get to one, head over to PangoVet. It's an online service where you can talk to a vet online and get the advice you need for your pet — all at an affordable price!

PangoVet_Mention-in-Content for PangoVet2 save money

What Are the Signs of Feline Hyperesthesia Syndrome?

Hypersensitivity to touch is the hallmark of FHS. This super sensitivity is accompanied by muscle contractions and behavioral changes, including aggression. Cats with the condition often vocalize excessively when a sensitive spot is stimulated. Some cats become fatigued and others engage in compulsive licking. Dilated pupils and skin rippling are other common signs.

The lower back is the most commonly affected area, with many cats exhibiting extreme sensitivity above the tail. If your cat shows FHS signs, contact your veterinarian and make an appointment. Cats that experience severe episodes that last 2 minutes or longer should be seen by a veterinarian immediately.

divider cats oct 2024

What Are the Causes of Feline Hyperesthesia Syndrome?

No one is sure what causes FHS. It could have dermatological, neurological, or psychological causes. Potential dermatological causes include allergies and immune system-related skin conditions. Neurological causes range from seizures to nerve pain. It could also have psychological causes linked to attention-seeking behavior or obsessive-compulsive disorder.

While no one is sure of the cause, veterinarians are certain that stress exacerbates the condition. Certain breeds, including Siamese, Burmese, and Persian cats, are predisposed to developing the condition. Scientists have been unable to isolate a specific gene responsible for the condition.

It’s most commonly diagnosed in young to middle-aged cats, with most cats being treated for the condition under the age of 7. Feline hyperesthesia syndrome isn’t linked to other physical problems, such as obesity or cancer.

Veterinarians are mostly limited to clinical sign management and mitigation regarding FHS. There’s no cure for the condition, but it’s possible to reduce your cat’s discomfort through environmental changes, behavior modification, and medication. Medication may be able to help with both pain relief and anxiety reduction.

hugging-an-adorable-bright-orange-cat-stress
Image Credit: RJ22, shutterstock

How Do I Care for a Pet With Feline Hyperesthesia Syndrome?

First and foremost, make sure you have a proper diagnosis. FHS is, in many ways, a diagnosis of exclusion, where veterinarians rule out other, more obvious causes for the behavior, such as arthritis and infections, before diagnosing a cat with the condition.

Cats with FHS can live long, healthy lives, though treatment is vital to keep the cat comfortable. Many veterinarians prescribe medications such as gabapentin, which works quite well regarding clinical sign reduction.

Anxiety reduction via medication and environmental measures is also important, as stress worsens the condition. Making sure your cat gets lots of exercise, providing food puzzles, and spending lots of quality time playing with your pet are great ways to reduce feline stress. They’ll also strengthen the bond you have with your pet!

Changes around the house often trigger feline anxiety. Many cats don’t do well with things like home renovations or the introduction of a new pet (or person) to the home.

Woman at home is giving a special medicine
Image Credit: Veera, Shutterstock

If your cat still needs a bit of help reducing their anxiety level even after you’ve made some structural changes, there are plenty of medications your veterinarian can prescribe that may help.

Never punish a cat for FHS-related behavior, including aggression. Cats cannot fully control their reactions or bodies when in the throes of an episode. Don’t try to intervene or calm your cat if they attack or lose control while petting them.

Continuing to touch your cat may actually make things worse. Allow your cat to calm themselves and return to their normal baseline before petting or picking up your buddy.

divider cats oct 2024

Frequently Asked Questions

Here, you’ll find answers to some of the most commonly asked questions regarding FHS.

What Are Some of the Other Conditions Feline Hyperesthesia Syndrome Resembles?

The condition often looks like a bad flea infection. Cats with parasitic infections will usually bite themselves to the point of injury due to the extreme itching caused by fleas and worms. The base of the tail is a popular hangout for fleas and an incredibly common spot for FHS to pop up. The condition can also resemble arthritis-related joint pain.

brown tabby cat with green eyes lying on the sofa, bites its nails
Image Credit: Magui RF, Shutterstock

Why Is Stress Reduction So Important?

No one is sure what causes the condition, but veterinarians almost universally agree that stress makes FHS worse. Because there’s no cure for the condition, treatment essentially involves managing attack frequency and strength. Stress reduction provides a tried-and-true way to reduce the severity of FHS and therefore, forms a core part of any treatment plan.


How Is Feline Hyperesthesia Syndrome Diagnosed?

The condition is most often a diagnosis of exclusion. There’s no blood test or imaging scan that a veterinarian can use to diagnose the disorder. Instead, veterinarians typically run a variety of tests to exclude other more common conditions, such as arthritis and various systemic diseases. Blood work, muscle biopsies, skin biopsies, X-rays, allergy tests, and MRIs may be used in diagnostic workups.

divider cats oct 2024

Conclusion

When touched, cats suffering from FHS often experience pain or uncomfortable sensations, causing some to react aggressively when being petted or handled. The condition most often affects cats’ lower backs, specifically the area right in front of the tail.

Some cats vocalize, and others bite the area after being touched in a sensitive spot. Uncontrolled jumping and dilated pupils are other signs that a cat is in the throes of an FHS attack. Cats experiencing pain from FHS are often unpredictable, so it’s best to leave any cat suffering from an episode alone until they’re back to normal.

See Also:


Featured Image Credit: biubiubiu23333, Pixabay

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything cat

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.

How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Catster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.

Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

Are Tulips Toxic to Cats? Vet-Reviewed Safety Information

Tulips are beautiful flowers, so there is no question why they are so popular. They are common inside and outside. Many cut flower...

How Far Apart Can Kittens Be Born? Vet Verified Facts

The amount of time a cat is in labor varies, but most kittens can be born between minutes to about an hour apart....

Bengal vs Tabby Cat: The Differences (With Pictures)

There are various similarities between the Bengal and the tabby. For example, they both have exotic-looking markings. The Bengal is known for their...

Wellness Cat Food Review of 2025: Recalls, Pros & Cons

Wellness Cat Food Review Summary Started in 1997 by a team of animal wellness experts, including nutritionists, veterinarians, and food scientists, Wellness Pet...

More related

Do Cats Like When You Sing to Them? Fun Facts

Even the shyest among us can feel confident belting out our favorite tunes in the comfort of home, and it’s even better when...

Inside the Exotic World of “Hong Kong Shop Cats”: Interview with Marcel Heijnen

New York City is the home of the esteemed bodega cat. These virtuous felines spend their time prowling the aisles of corner convenience...

Insect-Based Cat Food: Vet-Reviewed Pros, Cons & FAQs

You may have heard about the recent trend of pet food made with insects rather than more conventional animal protein. While this might...

Mouth Cancer in Cats: Vet-Reviewed Signs & When to Euthanize

One of the most difficult parts of pet ownership is making end-of-life decisions. Knowing when to euthanize a beloved animal companion is never...

Keep reading

Can Cats Drink Wine? Vet-Verified Safety Information

Many cat lovers appreciate a nice glass of wine in the evening to help them relax. Not only is it a crisp and refreshing drink, but it can also cut the edge after a stressful day and allow you to...

Can Cats Drink Wine

Made by Nacho Cat Food Review 2025: Recalls, Pros & Cons

Review Summary Made by Nacho is a love letter from celebrity chef Bobby Flay to his gorgeous orange tabby, Nacho, and his other tabby, Stella. Nacho is even considered a co-founder! Bobby Flay is an advocate for high-quality and tasty...

Made by Nacho Cat Food Review

How Do I Find a Lost Cat with a Microchip? Vet-Verified Facts & Safety Tips

Losing your cat is a situation no one wants to go through. You might have lived with the cat for years, and losing them can affect you emotionally. Since cats are territorial, their disappearance could mean that they are trapped,...

Beautiful well-groomed cat is lost_IRINA ORLOVA_Shutterstock

What Causes Mouth Ulcers in Cats? Our Vet Explains Signs, Causes & Prevention

Mouth ulcers in cats are spots in a cat’s mouth that can cause them to drool and not eat and intensify their bad breath. But there’s more to this condition in cats than just those signs. In fact, mouth ulcers...

veterinarian checks mouth of the maine coon cat

Can a Cat Detect Seizures? – What You Need to Know!

Most people know that certain dogs qualify as service animals under the Americans with Disabilities Act (ADA). Dogs have the ability to detect seizures in humans before they happen, and these dogs are known as seizure-alert dogs. While this ability...

Domestic cat lying on owner's lap

Why Is My Cat Bobbing His Head? 6 Vet-Verified Reasons for This Behavior

Head bobbing in cats can occur for a variety of reasons, some simple and others more serious. In many cases, your cat’s head bobbing may simply be the symptom of a benign, temporary anomaly, like a stressful situation or overheating....

woman hands pet and massage on the head of gray and white adorable cat

My Cat Makes Weird Noises When Drinking: 6 Vet-Verified Explanations

Are you worried that your cat has an odd way of drinking water? You’re not alone in this thought process. It’s a common question for cat owners, and usually, it’s nothing you need to worry about. Still, you’re probably just...

cat drinking water from bowl in carpet

How to Help Control Fleas in Feral Cats: 5 Vet-Approved Tips & Tricks

Most feral cats have difficult lives; one common problem they face is being infested with fleas. The parasites can be quite dangerous and lead to other diseases, which is why feral cats with fleas need our help. This article includes...

Beige or cream coloured cat scratching its ear