An orange cat with his mouth open — sneezing or hiccuping.
An orange cat with his mouth open — sneezing or hiccuping. Photography by Valery Kudryavtsev/Thinkstock.

New Breakthroughs in Treating Gingivostomatitis in Cats


Some unlucky cats develop a horrid mouth disease called gingivostomatitis, an immune-system issue that causes severe painful inflammation of the gums. In the worst cases, treatment is pulling out all the teeth. Even this doesn’t always work.

Stem cell research for feline gingivostomatitis.
Stem-cell research may help comabt feline gingivostomatitis. Photography © CIPhotos | Thinkstock.

A recent study published in the August 2017 journal Stem Cells Translational Medicine looked at stem cells as a treatment option for gingivostomatitis that doesn’t respond to treatment. Of the seven cats in the study, four had complete or significant remission (the other three saw no improvement). Although stem-cell research is still in its infancy, these are promising results.

Thumbnail: Photography by Valery Kudryavtsev/Thinkstock.

Jackie Brown is a freelance writer from Southern California, who specializes in the pet industry. Reach her at

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8 thoughts on “New Breakthroughs in Treating Gingivostomatitis in Cats”

  1. That’s exactly where I’m at now w/ MY kitty Squirt.
    He has Gingivostomatitis disease & needs all his back teeth pulled.
    A rough estimate is around $2,500 my Gosh I love my kitty but I’m not able to pay that. It’s breaking my heart thinking I might have to put him asleep because I’m too darn poor to pay that amount!!
    Are there any Vets that do Pro Bono work?
    Sincerely sad,
    Tina B.

    1. Hi Tina,

      These articles might help with affording vet bills. Hope your kitty feels better:

    2. Hallo , my cat was diagnosed with this terrible problem and we was before the horror treatment. I asked my vet if he can try to give my sweet cat an injection, VITAMIN C IV. He did agree, cat took I think 4 IV and the problem was gone, his gums was very nice pink and healthy. Next I was giving him vit c as a liquid supplement. Please, please try this.

  2. I had a cat with this problem and the vet just wanted to use steroids on him. It helped for a couple of weeks but then we were back where we started. At the vet’s suggestion I looked for info on the internet and found info on a University site about it. They said that sometimes pulling all the molars took care of the problem but sometimes they all had to be pulled. I told him what I found out and after about the third time he asked to fax him the print out I’d made from the website.
    Long story short we pulled all the molars, took him home the next day and he dug right into his food and in no time put the weight he had lost back on. He’s pretty old now and in poor health but pulling the teeth gave him a new lease on life and many years he wouldn’t have had otherwise. He never ever acted like he missed those teeth. No pain or howling when he’d eat. It was worth every penny.

  3. I was adopted by a beautiful mackerel tabby who appeared out of nowhere a few years ago…spayed and declawed, but in terrible physical condition. She has this disease. I have a wonderful vet who is treating her with interferon and recent partial tooth extraction. I would be interested in further info on stem cell treatment.

  4. I had a beautiful longhair orange tabby that developed stomatitis and it was horrible. He was treated a few times with antibiotics but it never lasted and we just couldn’t afford to have his teeth removed. Finally it became unbearable and I had to have him put down. He was only about 5 years old and had an amazing personality. I was and still am, sick about it.~~~ I’m so sorry O.J. :(

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