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10 Best Laundry Detergents for Cat Urine in 2026 - Reviews & Top Picks

By Kathryn Copeland
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grey cat sitting beside its pee spot on the rug

If you have a cat that tends to pee on your bedding or clothes, you’re not alone. Some cats pee on things other than inside their litter boxes for various reasons. They can be marking their territory, there might be a health problem, or perhaps your cat is not entirely happy with you.

Whatever the reason, if you are regularly dealing with cat urine-stained clothing or bedding, you’re obviously in the market for laundry detergent that can deal with this kind of odor. But where to start?

We look at what the best cat urine laundry detergent or pre-treatments are that can handle this kind of stubborn stain and smelly odor. We hope that our reviews will help you find the best laundry product to deal with your particular situation.

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A Quick Comparison of Our Favorites of 2026

Rating Image Product Details
Best Overall
Winner
Nature’s Miracle Laundry Boost Nature’s Miracle Laundry Boost
  • Trusted company for 35 years
  • Can be used as a pretreatment
  • Phosphate-free
  • Best Value
    Second place
    Lysol Laundry Sanitizer Additive Lysol Laundry Sanitizer Additive
  • Kills 99.9% of bacteria
  • Doesn’t contain bleach or phosphates
  • Can be added to your regular detergent
  • Premium Choice
    Third place
    Skout’s Honor_ Professional Strength Laundry Booster Skout’s Honor: Pro Laundry Booster
  • No harsh chemicals and is biodegradable
  • 100% satisfaction guarantee for full refund
  • With every bottle sold, the company donates a day’s worth of food to a needy animal
  • Febreze Laundry Pet Odor Eliminator Febreze Laundry Pet Odor Eliminator
  • Can use to pretreat before washing
  • Can be used in HE washing machines
  • Eliminates pet odors instead of just masking them
  • LaundraPet Premium Laundry Detergent LaundraPet Laundry Detergent
  • Washes up to 96 loads
  • Cleans 3x better than other detergents
  • Made without soap
  • The 10 Best Laundry Detergents for Cat Urine

    1. Nature’s Miracle Laundry Boost – Best Overall

    Nature’s Miracle Laundry Boost
    Size:32 oz
    Liquid or Powder:Liquid
    Detergent or Additive:Additive
    Scented:Yes

    The best laundry additive for cat urine is Nature’s Miracle Laundry Boost. This isn’t actually a detergent, but it can be used as a pretreatment and an addition to your usual laundry detergent. Nature’s Miracle was made specifically to deal with stains and odors caused by pets, including blood, vomit, and cat urine. It’s phosphate-free but still works to get rid of old stains and odors. It is safe to use in your laundry (although, always read and follow the directions first).

    The main disadvantages are that not everyone will find that the urine smell will disappear (at least not right away), and the company recently redesigned the bottle, which seems to be more difficult to use.

    Pros

    • Can be used as a pretreatment and with regular detergent
    • Designed to handle cat urine, as well as blood, vomit, feces, etc.
    • Trusted company for 35 years
    • Phosphate-free but will still clean stubborn stains and odors

    Cons

    • Not every cat owner will be satisfied with the results
    • Redesigned bottle difficult to use

    2. Lysol Laundry Sanitizer Additive – Best Value

    Lysol Laundry Sanitizer Additive
    Size:41 oz
    Liquid or Powder:Liquid
    Detergent or Additive:Additive
    Scented:No

    The best laundry booster for the money is Lysol Laundry Sanitizer Additive. This is not a cat urine laundry detergent, but it is designed to be added to the laundry with your regular detergent or can be used on its own to remove stains and odors (and bacteria). This product is used by commercial laundry services to remove tough stains and odors. It can kill 99.9% of all kinds of bacteria, including pathogenic and odor-causing bacteria. It doesn’t contain bleach or phosphates and can work on cat urine.

    On the downside, while it doesn’t affect everyone, some people seem to come down with some form of rash or hives when coming into contact with fabric that has been washed with this product. You might want to avoid this product if you have sensitive skin.

    Pros

    • Good price
    • Can be added to your regular detergent
    • Kills 99.9% of bacteria
    • Doesn’t contain bleach or phosphates

    Cons

    • Some people might develop hives or rash

    3. Skout’s Honor: Professional Strength Laundry Booster – Premium Choice

    Skout’s Honor_ Professional Strength Laundry Booster
    Size:32 oz
    Liquid or Powder:Liquid
    Detergent or Additive:Additive
    Scented:Yes

    Our pick for premium choice for the best cat urine remover is Skout’s Honor Professional Strength Laundry Booster. This is an additive rather than actual laundry detergent, but when used with your detergent, it will remove cat urine stains and odors. It is biodegradable and environmentally friendly because it doesn’t contain any harsh chemicals. Skout’s Honor is designed to remove tough odors and stains such as vomit and blood (in addition to the urine), and it offers a 100% satisfaction guarantee for a full refund. In addition to all this, it also provides a day’s worth of food for a needy animal for every bottle sold.

    However, it is expensive, and it might not necessarily work on all odors. You should do a small spot-check before use, as discoloration might occur.

    Pros

    • Additive that eliminates cat urine stains and odors
    • No harsh chemicals and is biodegradable
    • Removes tough stains and odors (urine, vomit, blood, etc.)
    • 100% satisfaction guarantee for a full refund
    • With every bottle sold, the company donates a day’s worth of food to a needy animal

    Cons

    • Expensive
    • Might not always remove the odor
    • Discoloration might occur

    4. Febreze Laundry Pet Odor Eliminator

    Febreze Laundry Pet Odor Eliminator
    Size:98 oz
    Liquid or Powder:Liquid
    Detergent or Additive:Additive
    Scented:Yes

    Febreze’s Laundry Pet Odor Eliminator is an additive that you use along with your laundry detergent. It is designed to eliminate odors instead of just covering them and is specifically meant for pet odors. It can be used to pretreat before washing and is safe to use with all detergents, fabric softeners, and bleaches. It can also be used in HE washing machines.

    Unfortunately, it is a little expensive, and it might not be as effective on older stains that have had time to set in.

    Pros

    • Eliminates pet odors instead of just masking them
    • Can be used to pretreat before washing
    • Can be used in HE washing machines
    • Safe to use with all bleaches, fabric softeners, and detergents

    Cons

    • Expensive
    • Not as effective on older stains

    5. LaundraPet Premium Laundry Detergent

    LaundraPet Premium Laundry Detergent
    Size:64 oz
    Liquid or Powder:Liquid
    Detergent or Additive:Detergent
    Scented:Yes

    LaundraPet Premium Laundry Detergent is suitable for pet stains and odors and can clean up to 96 loads of laundry. It is made with non-soap ingredients that provide three times the cleaning power of other detergents and is also low suds and non-toxic.

    The disadvantages are that it is on the pricey side, and it won’t always be able to remove the cat urine odor.

    Pros

    • Detergent for pet stains and odors
    • Washes up to 96 loads
    • Made without soap and is low suds and non-toxic
    • Cleans 3x better than other detergents

    Cons

    • Expensive
    • Might not be able to remove odors

    6. Persil ProClean Power-Liquid Laundry Detergent

    Persil ProClean Power-Liquid Laundry Detergent
    Size:100 oz
    Liquid or Powder:Liquid
    Detergent or Additive:Detergent
    Scented:No

    Persil’s ProClean Power-Liquid Laundry Detergent is great for people with sensitive skin and does not contain any perfumes or dyes. It can wash up to 64 loads and is designed to be gentle on skin and fabric but provides strong cleaning power. It is phosphate-free and hypoallergenic.

    The biggest problem with this detergent is the packaging. Many containers arrive leaking, so you might want to consider buying this one in a store rather than through delivery.

    Pros

    • Good for sensitive skin
    • Does not contain perfumes or dyes
    • Gentle on fabric and skin but strong cleaning power
    • Hypoallergenic and phosphate-free

    Cons

    • Containers tend to leak during delivery

    7. Zero Odor Laundry Odor Eliminator

    Zero Odor Laundry Odor Eliminator
    Size:16 oz
    Liquid or Powder:Liquid
    Detergent or Additive:Additive
    Scented:Yes

    Zero Odor Laundry Odor Eliminator works as an additive to your cat urine laundry detergent or regular detergent to eliminate smelly odors from sweat, smoke, and pets. It is also designed to clean your washing machine at the same time. It is biodegradable and non-toxic and doesn’t cover up odors with perfume.

    On the downside, while the label states that it doesn’t use perfumes to mask odors, this product has an unmistakable scent, so it’s not hypoallergenic. It is also somewhat expensive.

    Pros

    • Additive good for sweat, smoke, and pets
    • Deodorizes the washing machine at the same time
    • Doesn’t mask odors with perfume
    • Non-toxic and biodegradable

    Cons

    • Scented, so not hypoallergenic
    • Expensive

    8. All Liquid Laundry Detergent

    All Liquid Laundry Detergent
    Size:88 oz
    Liquid or Powder:Liquid
    Detergent or Additive:Detergent
    Scented:No

    All’s Liquid Laundry Detergent is a great laundry detergent if you have sensitive skin. It contains no dyes or perfumes, and it has enough for about 49 loads. This detergent is advertised as the number-one brand recommended by dermatologists, pediatricians, and allergists, and it is effective against cat urine.

    The issues with this detergent are that it isn’t always effective against odors, and it tends to arrive leaking during delivery.

    Pros

    • Good for sensitive skin
    • Doesn’t contain dyes or perfumes
    • Enough for 49 loads
    • Chosen as the best detergent by dermatologists, pediatricians, and allergists

    Cons

    • Isn’t always effective against odors
    • Might arrive leaking during delivery

    9. Dead Down Wind Laundry Detergent

    Dead Down Wind Laundry Detergent
    Size:40 oz.
    Liquid or Powder:Liquid
    Detergent or Additive:Detergent
    Scented:No

    Dead Down Wind Laundry Detergent is made for hunters as a way to keep odors down so they can’t be scented while outdoors. It can work just as well for cat owners looking to eliminate that urine smell. It works for sensitive skin, is unscented, and contains enzymes to help break down stains and odors. This cat urine laundry detergent cleans clothes, removes odors, and protects your fabrics, which enables them to last longer.

    The primary disadvantage is that during delivery, some of the bottles are prone to leaking.

    Pros

    • Good for sensitive skin
    • Unscented and contains enzymes for stains and odors
    • Cleans clothes and eliminates odors and fabric lasts longer

    Cons

    • Might leak during delivery

    10. Biz Laundry Detergent Powder Booster

    Biz Laundry Detergent Powder Booster
    Size:50 oz
    Liquid or Powder:Powder
    Detergent or Additive:Additive
    Scented:Yes

    Biz Laundry Detergent Powder Booster is an additive for your laundry detergent, and it contains enzymes that are effective against cat urine. It also includes whitening and peroxide agents to help whiten your wash and add extra power against stubborn stains and odors. You can pre-treat or pre-soak the fabrics before washing and add it to the washing machine for additional effectiveness.

    However, you might find it to be a little on the expensive side (at least compared to some others), and some users might not find it effective enough against odors.

    Pros

    • Contains enzymes that work well against cat urine
    • Includes peroxide and whitening agents
    • Pre-treat, pre-soak, and use in every wash

    Cons

    • A little expensive
    • Might not be as effective against odors
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    Buyer's Guide: Selecting the Best Laundry Detergents for Cat Urine

    Before you decide on a new detergent or additive, you might want to check out our buyer’s guide. We go over a few things that you'll want to think about before paying for a product.

    Image Credit: Africa Studio, Shutterstock

    Scented or Unscented

    Most additives and detergents will be scented. If you don’t mind a strong, perfumey scent, this is nothing to worry about. But if you have allergies or sensitive skin, you’ll want to check the ingredients before purchasing. It’s important to note that a strong fragrance won’t remove the scent of cat urine from your clothing. You want to aim for something that eliminates the odor and not just covers it up.

    Enzymes

    The use of enzymes is the most effective way to remove cat urine odors from anything. They work to break down the urine’s pH to remove odors and stains. This will also help prevent your cat from urinating in the same spot repeatedly because that scent will disappear and won’t keep drawing your cat.

    Did you know there's an enzyme cleaner that does it all? The Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray permanently removes the very worst smells and stains (truly, everything you can imagine!), and they offer a 100% satisfaction guarantee! Click here to get yourself a bottle.

    Our recommendation
    Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray
    Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray
    • ADVANCED ENZYMATIC CLEANER - Penetrates the most stubborn smells and stains at the deepest molecular levels to dissolve any pet mess you encounter and lift it away at the source.
    • FOR ANY MESS, ON ANY SURFACE - This pet odor eliminator cleans your carpets, floors, furniture, fabrics, and more. Whether it's urine, feces, vomit, or drool, you can erase all foul spots and smells!
    • FRESH, NATURAL ODOR - Our unique formulation doesn't rely on dangerous or unpleasant chemical fragrances to get the job done. We eradicate smells and stains, not just cover them up.

    At Catster, we’ve admired Hepper for many years, and decided to take a controlling ownership interest so that we could benefit from the outstanding products of this cool cat company!

    Testing

    When you are trying to eliminate tough scents and stains, the additive and detergent tend to be stronger. You must test a spot (particularly on a more delicate fabric) in a more hidden area before throwing it into the wash entirely. This way, you won’t accidentally ruin your favorite shirt or blanket.

    If your cat experiences frequent pee accidents,you should have your vet assess them for underlying health issues.

    Delivery

    Many negatives of these products tend to be about leaking during delivery. This isn’t a common occurrence but it’s always a possibility. We don’t know for certain if it is due to the design of the containers or the delivery service itself, but it’s good to be aware that this could happen, and you might want to consider shopping for the product in person.

    Time

    The older the stain, the longer you will want to pre-soak it before actually washing it. Double-check the product before purchasing and read the instructions carefully. Not every detergent or additive will work on old stains.

    Image Credit: cunaplus, Shutterstock
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    Our Laundry Detergents for Cat Urine Selection Process

    Catster’s dedicated team of writers and editors collaborate with expert veterinarians, considering a wide range of factors when selecting the best laundry detergents for cats. These parameters include customer reviews, brand reputation, veterinary experience, and in some cases, hands-on testing. Of course, our cats have a say in the process, too! We strive to select and review the highest-quality products available, to help you choose the best possible product and make the most informed decision for your and your cat’s needs.

    Why Trust Catster?

    Catster has been a trusted online brand since 2001, so we know a thing or two about laundry detergents for cat urine. We’re a team of cat-loving writers, editors, and veterinarians dedicated to helping you make the most informed decision for your feline. We deeply believe in providing the best information for cat owners to help their cats live their best life possible. We look at reviews from the most trusted sources available, and this, combined with our veterinary team’s experience and expertise, helps us gather the best options on the market. Our team is invested in the welfare and health of cats around the world, and believe that expert knowledge is one of the best ways to achieve this.

    divider 2 cats

    Summary

    We hope that these reviews will help you find the right detergent (or additive) that works best for you. Our pick for the best overall additive product is Nature’s Miracle Laundry Boost because of its use of enzymes for breaking down those odors. We picked the Lysol Laundry Sanitizer Additive as the best value product for killing off harmful bacteria at a great price.

    Finally, our choice for a premium additive is Skout’s Honor Professional Strength Laundry Booster because it's an environmentally conscious product, and the company clearly cares about pets!


    Featured Image Credit: New Africa, Shutterstock

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