Get

In Your Inbox

Catster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

Immunotherapy for Cat Allergies: Our Vet Explains How It Works

Immunotherapy Diagnosis

Do you love cats but are overwhelmed by the watery eyes, runny nose, and scratchy throat whenever they come near? Perhaps it is your loved one who is the cat lover and you are worried how you’ll fare if they have to choose between you and the cat. The good news is that there are options available that may make it possible for you to share your home with a feline friend, despite your allergies.

divider 3 paws

The Basics of Immunotherapy for Cats Allergies

It’s a common misconception that people who are allergic to cats are reacting to the fur, as this isn’t exactly the case. As with most allergies, the immune system is reacting to proteins, called antigens, found in tiny particles of dead skin cells (dander), saliva, oils, urine, and feces that cling to the fur and become airborne when cats shake, scratch, or groom themselves. Different cats can have different proteins, so some people with cat allergies may not be allergic to all cats.

If you are thinking about trying immunotherapy for your cat allergies, there are a few things to consider first:

woman-sneezing-beside-a-cat
Image Credit: Motortion Films, Shutterstock

Are You Definitely Allergic to Cats?

This is probably obvious to you, but there is always a chance that it’s not cats, or not just cats, that are causing your symptoms. You’ll need to talk to your doctor about allergy testing, so make sure they are testing for all environmental allergens, as well as the different types of proteins carried by cats.

Other Ways to Manage Cat Allergies

Before exploring immunotherapy to tackle this problem, there are some simple ways to minimize your allergy exposure:

  • Regular vacuuming with a powerful cleaner that uses a HEPA filter
  • Air purifiers to reduce airborne allergens
  • Keeping cats out of the bedroom
  • Regular cleaning of bedding
  • Talk to your doctor about strong antihistamines
  • Look into breeds that produce lower allergen levels
  • Keep your cat brushed and groomed regularly (preferably by someone else!)
young woman using an air purifier at home
Image Credit: Yuttana Jaowattana, Shutterstock

divider 3 paws

What Is Immunotherapy and How Does It Work?

People who suffer from allergies are experiencing a hypersensitive immune reaction to the allergen(s). Essentially, their immune system is overreacting. This leads to a flood of inflammatory cells, including histamine, which is responsible for the swelling, itching, redness, and oozing that allergy sufferers are familiar with.

Antihistamines, decongestants, and corticosteroids can be used to suppress or mask the allergic response, but it is only a temporary solution that does not address the underlying problem.

Immunotherapy uses increasing doses to “train” your immune system to get used to the allergen, slowly and safely desensitizing it with controlled levels. This has traditionally been in the form of injections, but there are more options emerging.

Let’s take a look at some of the immunotherapy options that are available now, or those that soon will be.

Types of Immunotherapies for Cat Allergies

Allergen-Specific Immunotherapy (ASIT or AIT)

Following allergy testing, a formula containing the specific allergens required (which may be more than one) is created. There are two ways this can then be administered:

Subcutaneous Immunotherapy (SCIT) - Injections
  • Weekly injections increase in concentration until the full dose is reached. The injections are then given monthly for a period of around 3 years, by which time some people are able to stop the injections, while others need to continue regular treatments.
  • Usually covered by medical insurance.
  • Requires regular visits to the doctor’s office.
  • Higher risk of reactions/side effects.
Sublingual Immunotherapy (SLIT) - Drops or Tablets
  • Daily dosage with liquid drops or a tablet placed under the tongue. Can be started at the full dose, or with a short period of increasing from the low dose.
  • More convenient, as treatment can be done at home.
  • May not be covered by medical insurance.
  • Lower risk of side effects.

woman getting injected
Image Credit: HenadziPechan, Shutterstock

Combined ASIT and Tezepelumab

A recent study did a trial combining SCIT injections with the antibody Tezepelumab, which blocks the action of a specific protein that has been linked to asthma and allergic disease. Results have indicated that using a combination of Tezepelumab with SCIT for 12 months resulted in better, longer-lasting results than either method alone. This may be the next big step in managing reactions to numerous allergens, including cats.

divider 3 paws

Frequently Asked Questions (FAQs)

How Do I Get Started?

Your first step is to talk to your doctor. From there, how you proceed will vary greatly based on the individual and your doctor.


How Long Will It Take to Feel Better?

Again, it depends on the individual. Some patients notice improvements within several weeks, while others won’t notice improvements for months.

divider 3 paws

The Takeaway

If you suffer from cat allergies and want to do something about it, talk to your doctor. Even now, new methods are being developed that can help allergy sufferers have a better quality of life, which can only be improved further if they can share that life with a cat!


Featured Image Credit: Marcelo Ricardo Daros, Shutterstock

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything cat

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.

How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Catster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.

Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

Ways I Irritate My Cat: What Olga Endures

Hi, I’m Christopher! Read my introduction to learn more about me and my silly Russian Blue cat, Olga. Living with a cat is...

Can Cats Eat Tuna? Vet-Reviewed Nutrition Facts & FAQ

Tuna is one of the human foods most offered to cats, either as a treat or part of their daily diet. However, just...

Can Cats Eat Onions? Vet-Reviewed Risks & Dangers

Any cat owner knows that our felines don’t always make the best choices about what they put in their mouth. Even the pickiest...

How to Care for a Tortoiseshell Cat: 9 Vet-Approved Tips

You’ve decided to adopt a Tortoiseshell cat and give them a forever home. Now, you’re wondering how to care for your new little...

More related

Can Cats Eat Sugar? Nutrition Facts & FAQ (Vet Answer)

Terminology: The term sugar is used in this article to describe sucrose (composed of fructose and glucose), rather than the complex carbohydrates, structural...

Lilac Tortoiseshell Cat: Info, Pictures, Facts & History

A tortoiseshell cat is distinguished by its coat, which resembles the color pattern of a tortoise shell. The coat is usually a mixture...

Fluid in a Cat’s Lungs: Symptoms, Care, & Treatment (Vet Answer)

Fluid in the lungs, also known as pulmonary edema, is a serious condition that affects felines. If your cat receives this diagnosis from...

Is Coleus Toxic to Cats? Vet Approved Advice

Even if you don’t know it, you probably have seen beautiful coleus plants in people’s homes and gardens. These colorful plants are common...

Keep reading

Can Cats Eat Chicken Nuggets? Vet-Verified Facts & FAQ

Picture this: You’re eating some dinner one night, and your furry friends gather around you. Those sweet eyes are hard to resist, but you wonder if it’s safe to feed them human food. What should you do? Well, it depends...

Can Cats Eat Chicken Nuggets

Can Cats Eat PopTarts? Vet-Reviewed Facts & FAQ

“Curiosity killed the cat” is a phrase that couldn’t be truer about some cats. It seems like you can’t leave them alone for more than a minute before they’re face first in something they’re not supposed to touch. The good...

Can Cats Eat PopTarts

8 Best Wet Cat Foods in Australia in 2025 – Reviews & Top Picks

There are many benefits to introducing wet cat food into your cat’s diet. It contains more moisture to help your cat stay hydrated, and it’s easier to eat and digest for older cats and cats with digestive issues. However, even...

orange cat eating wet food

How Do Cats Walk? Our Vet Explains

Any cat owner whose ankles have fallen victim to a sneak attack from a playful kitty knows that sometimes you can’t hear them coming! But have you ever wondered precisely how cats walk and how they are so stealthy about...

cat walking

5 Best Litter Box Ramps for Senior Cats in 2025 – Reviews & Top Picks (Vet-Verified)

As cats get older, they face various challenges and may even need special tools to help them get through the day. One example is a litter box ramp that can help them enter and leave as needed. If you have...

iPrimio Cat Scratch Ramp

Do Cats Eat Christmas Trees? Vet-Reviewed Risks & Tips

Christmas is a magical time that fills our homes with warm smells and sparkly lights. Only, cat owners have to deal with the constant chaos of owning a Christmas tree with a pet. Christmas trees, both live and artificial, can...

cat hiding in the Christmas tree

How to Treat a Cat Scratch: 6 Vet-Approved Steps

It’s no secret that our kitties love using their claws! Whether it’s for play, balance, hunting, or climbing, they work best with their claws out. However, if you get in the way, it won’t fare well for your fragile skin....

scratch on a man's hand made by a cat

Why Is My Cat Peeing on My Bed All of a Sudden? 5 Vet-Reviewed Reasons

Have you ever had to ask yourself “why did my cat pee on my bed”? Us too. As cat owners, we love our cats but we don’t love their pee. It’s pungent and difficult to remove from places outside of...

cat-peeing-on-the-bed