Get

In Your Inbox

Catster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

Depression in Cats: Our Vet Answers Signs, Causes & Treatments

Share

sad looking cat lying on a table

Clinical depression is a medically recognized and fairly common mental health disease of humans. Feelings of sadness and behavioral changes such as lack of motivation to perform regular activities, or disruption of sleeping patterns are some of the signs of this disease. Depression is considered a multifactorial disease1. Sometimes depression is caused by a clear emotional trigger, such as the separation or loss of a loved one, financial difficulties, etc. Clinical depression can also be caused by chemical imbalances in the brain. What is certain is that depression in humans can be easily diagnosed due to our ability to verbally express our feelings.

The observation of behavioral changes similar to those experienced by humans with diagnosed clinical depression are the reason why some cat owners think their cat is suffering from depression.

divider cats oct 2024

Can My Cat Suffer From Depression?

Cats, just like any other animals, are sentient beings and can suffer from mood disorders. Because cats can not express themselves verbally, it is wiser to avoid evaluating them using humanized adjectives or characteristics and instead focus on evaluating them from a more cat-friendly perspective. This will help you better understand and provide the needed solutions for your beloved cat’s “depression”.

sad looking cat lying down
Image Credit: pasja1000, Pixabay

What Are the Signs of “Depression” in Cats?

  • Loss of appetite
  • Activity levels notably decreased
  • Loss of interest in their favorite toys
  • Avoiding owner
  • Abnormal aggressive behavior such as hissing or biting
  • Change in sleeping patterns
  • Change in cat litter box usage
  • Aberrant, self-mutilating behaviors such as biting, pulling hairs out, or excessive licking of paws

It is common for concerned cat owners to assume their cats are suffering from depression upon observation of one or more of these behavioral changes in their cat. However, all of these signs can have several different causes, including pain and discomfort from a disease, injury, or other health problems. To better help our beloved furry friends, we need to collect as much information as possible. This will allow us to have a clearer idea of what is going on.

It is very important to address the issue as soon as possible for two reasons:
  • If the issue is behavioral: It is way easier to address the problem and take actions to correct and change the behavior before the issue of concern turns into a habit. The faster we respond, the less habituation of the specific behavior and the easier it will be to work towards eliminating them.
  • If the sign is due to a medical condition: There are greater chances for successful treatment and recovery when the cause of the disease is found earlier. Medical issues tend to complicate over time, or, in the worst-case scenario, in a matter of hours.

Seek veterinary advice if you’re concerned about your pet’s well-being.

If you need to speak with a vet but can't get to one, head over to PangoVet. It's an online service where you can talk to a vet online and get the advice you need for your pet — all at an affordable price!

PangoVet_Mention-in-Content for PangoVet2 save money

What Can I Do if My Cat Shows Signs of Depression?

Once we identify that the cat shows any of the mentioned signs, it is important to start gathering information systematically. Cats do not speak about their emotions, but what is certain is that the change of behavior has a cause, and we should make an investigation of what is going on.

divider cat faces 2 oct 2024

A Guide to Gathering Relevant Information

The Environment:

Identify if there is any change in the environment that happened just before or around the time when your cat’s behavior started changing.

Here are some examples:
  • Your cat has reduced or lost appetite. Has there been a change in the cat food brand, the plate, the placement of the plate, or anything you can identify as different from before?
  • Your cat is refusing to use the litter box. Has there been any change in the box, the litter brand, the placement of the box, or the frequency of cleaning it?

Cats are known to be creatures of habit, and sometimes the smallest changes in the environment can cause behavioral changes in your cat.

Yourself or Any Other Member of the Family:

You notice your cat has suddenly been presenting avoidance behavior towards you. Try to identify if you have changed something in yourself. You are one of the most important parts of your cat’s social environment, and although cats are considered to be very independent pets, your behavior has effects on them.

Have you changed your perfume? Are you going through some stressful situation? Have your hours at home changed? Is there a new member in the family or a friend visiting more often than before?

Cats tend to be independent creatures that feel safe with their habitual routines. However, for some cats, changes in their social environment and routines can cause them anxiety. Anxiety is very often the reason behind behavioral changes in cats.

cat-pooping-outside-the-litter-box
Image Credit: Tanya Plotnikova, Shutterstock

Other Cats:

If you have more than one cat, it is always important to evaluate the social interactions and structure between the members of the group. In the case where one of your cats has a reduced appetite and seems to be losing weight, chances are that they are being displaced by one of the other cats. Having multiple feeding stations on opposite sides of the room might solve this problem.

If one of your cats is urinating outside the litter box, chances are other cats are also claiming the box as their property or territory and displacing them. In this case, providing multiple litter boxes could be the solution. In fact, if you have a multi-cat household, the rule is one litter box per cat, plus an extra one.

If you have more than one cat in your home, it is very important to provide an environment that allows the healthy socialization of the cats. Anxiety and chronic stress can have a very negative impact on a cat’s behavior and health; aberrant self-mutilating behaviors can sometimes be tracked right back to anxiety.

When having a multiple cat household it is always recommended to provide a “safe space” for each cat. Cats prefer higher-up spaces that provide a sense of security and protection for hiding spots. Providing a comfortable and easy-to-access place for each cat to have a safe place and their “own” territory might do wonders in reducing anxiety in the cats.

divider cats oct 2024

Should We Visit the Veterinarian?

If the cat’s behavioral changes or anxiety were caused by any changes in the routine or social or environmental factors, the cat’s behavior should return to normal a few days after resuming habitual routines and “normality”. However, it is always a good practice to get advice from a veterinarian.

If you can not identify any change in the routines or the social or physical environment, it is very important to visit a veterinarian as soon as possible. All the signs that we listed and that are claimed to be signs of “depression” in cats are non-specific and could be due to an underlying health issue. Loss of appetite can be caused by something as simple as a small injury in the mouth or by multiple gastrointestinal problems ranging from gastritis to cancers. As well, kidney disease presents with loss of appetite and changes in litter box usage.

As a general rule, it is better to visit the veterinarian sooner rather than later, because while some diseases have a slower course, others complicate within a matter of a day or two, such as in the case of urethral obstructions in male cats.

vet checking up the cat
Image Credit: Maria Sbytova, Shutterstock

How Does the Veterinarian Get an Appropriate Diagnosis?

It is always recommended to provide a veterinarian with all the information you have gathered from your cat’s case.

These are some useful questions to guide you with the information you should provide:
  • What is the approximate age of your cat?
  • How long have you been “their human” (time of ownership)?
  • What are the signs of concern you have noticed in your cat?
  • When did the signs start?
  • Did you notice any change in the physical or social environment of the cat?
  • Has there been any change in your routines? For example, a new job changes the normal times you are around home.
  • Do you have other cats in the same household? And if yes, please specify their sex and other relative information.

By bringing all this information, you will help the veterinarian to better understand the case and general situation, adding to better diagnosis and potentially saving you some money. In some cases, differentiating anxiety from other very serious medical conditions, such as infections or tumors involving the nervous system, is done by elimination. This translates into a veterinarian having enough information that might save you from paying for extra diagnostic tests such as biopsies, X-rays, or even MRIs. Cats never behave the same in the clinic as they do in their home environment, so your behavioral observation is of great value for the clinical history.

divider cat faces 2 oct 2024

Testing Toward Diagnosis

After understanding the specifics of the case’s history, a veterinarian will proceed to perform a complete physical examination of the cat. After completing the physical examination, the veterinarian will collect a biological sample of your cat’s blood, and maybe also urine or fecal samples.  If more information is needed, the veterinarian might also use some diagnostic imaging such as X-rays, ultrasounds, or even an MRI.

After performing the necessary tests and having an appropriate diagnosis of what is causing your cat’s unusual behavior, the veterinarian can address any medical conditions such as infections, injury, or pain with appropriate treatments.

Pain in cats is commonly confused by owners with what they describe as “depression.” For this reason, it is always recommended to bring your cat for a medical evaluation if you notice any behavioral change that concerns you.

Important:

Always follow a veterinarian’s advice and prescriptions, and never try to medicate your cat. Keep in mind that several over-the-counter pain management medications for humans are toxic and even lethal for cats.

divider cats oct 2024

What Is the Treatment for “Cat Depression”?

Closeup veterinarian is making a check up of a adult maine coon cat with stethoscope in vet clinic
Image Credit: Ermolaev Alexander, Shutterstock

Based on the specific case history, the physical examination observations, and the results of the diagnostic test, the veterinarian will develop an appropriate plan to aid your furry friend. If the issue is caused by a medical condition, a variety of treatments ranging from oral medications to surgery will be indicated following the specific medical case.

If the veterinarian has ruled out a disease or underlying medical condition he or she might recommend a consultation with a cat behaviorist and/or start treating your cat for “anxiety”.

The treatment might include the addition of pheromone diffusers to the environment. Pheromone diffusers look like electronic air fresheners, they plug into electrical outlets and required periodic cartridge changes. The cartridge contains synthetic chemicals that mimic naturally occurring pheromones and have a calming effect on the cat’s condition. If this is the case, it is very important to be very specific about what kind of pheromone blend you are looking for. There are a variety of blends in the market; Feliway for example offers good quality products and different compositions for a single pet cat or multiple pet cats sharing a home.

If the veterinarian suspects that pain is the reason for your cat’s ” depression” they might prescribe pain management treatments. The drug of choice will depend on the pain’s location and origin.

In addition, the veterinarian might prescribe your cat anxiolytic medications or a lighter calming supplement.In any case, the recommendation is to follow the veterinarian’s advice very specifically with regards to the dosage and frequency of the medication. A good cat owner’s practice is to always keep your cat under observation while under new medical treatments. Contact your doctor immediately if you notice something that concerns you.  Never give your cat any medication without the prescription and advice of a veterinarian as you might be increasing the cat’s risks instead of helping them.

divider cat faces 2 oct 2024

Final Thoughts

As a responsible cat owner, the best you can do for your cat is to understand that yes, when a cat’s behavior changes, there is something going on that needs careful evaluation and addressing. You can provide the best value by learning to note these behavioral changes, collecting all relevant information, and taking your cat to a veterinarian’s consultation as soon as possible to rule out any dangerous underlying condition.

See Also:


Featured Image Credit: avi_acl, Pixabay

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything cat

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.




How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Catster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.


Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

What Feral Cats Actually Need From the People Who Feed Them

Feral cats are everywhere. Slipping between parked cars, darting under porches, appearing briefly at dusk before vanishing again. Most people see them, feel...

Capturing Catstanbul

Istanbul – famous for its bustling markets, unique architecture, and vibrant culture, there is one more feature of this Mediterranean capital that deserves...

Ask Dr. Paola – Help! My Male Cat Gets Into Fights! (March 9, 2026)

Welcome to our “Ask Dr. Paola” series, where every Monday we bring expert advice straight from Dr. Paola Cuevas (MVZ) to help our...

Why Your Cat’s Poop Smells Like a Biohazard

Nobody enjoys litter box duty, but sometimes it gets unbearable. The smell hits you from across the room. You’re scooping faster, lighting candles,...

More related

Siamese Ragdoll Cat Mix: Info, Pictures, Temperament & More

Siamese-Ragdoll cat mixes are gorgeous hybrid animals featuring the best qualities of each of these popular breeds. Also known as Ragamese, these cats...

Cat Art Show 2 Draws 7,000 People to a Los Angeles Gallery

On March 24 – March 27 2016 in Los Angeles, more than 7,000 people visited a gallery to see artwork featuring cats. Breathe...

Kidney Failure in Cats: Vet-Reviewed Facts & When to Euthanize

Most of us wish our pets could live forever, but unfortunately, we dream the impossible dream. While no pet owner wants to face...

Can Cats Eat Stevia? Vet-Reviewed Facts & FAQ

These days, you can find many different types of zero-calorie sweeteners and sugar substitutes. Each type has different compositions, so some may be...

Keep reading

Is It True That All Stray Cats Have Fleas? Vet-Verified Facts & FAQ

It is fair to assume that all stray cats have fleas simply because they are more likely to be exposed to other animals infested with fleas. If a stray cat has been on the streets for a long time, they...

stray cats lying on the ground

How Do Cats Know to Use the Litter Box? Vet-Verified Facts & Useful Tips

Have you ever considered how cats seem to instinctively know where to go when nature calls, while dogs often require dozens of potty-training repetitions? What makes cats such tidy creatures? Are their brains naturally wired for cleanliness? Despite what many...

Domestic ginger cat looking at litter box

What If Your Cat Isn’t a Lap Cat? 6 Vet-Approved Reasons They May Not Want to Sit With You

Cats are just so unique! Some cats are super energetic, while others are quite calm. Many cats are standoffish, but just as many are cuddly. So, why are some cats not lap cats? This can be disappointing for some owners....

A cat near his human on the couch and computer.

Why Is My Cat Scratching the Walls? 6 Likely Reasons

Cats do what they want to do. If you have cats in your home, you’re already fully aware of this. Unfortunately, there are times when our beloved kitties push the boundaries and do things around the house they shouldn’t be...

cat trying to climb a wall

Will Insulation Hurt My Cat If They Touch It? Vet-Reviewed Prevention Tips & Safety Info

Most (but not all) wall or hardware insulation isn’t going to harm your feline if they only touch it. However, it isn’t digestible, so if your feline eats it, it can cause chemical toxicities and/or gastrointestinal blockage. Such incidents are...

Foam construction insulation

10 Best Lysine Supplements for Cats in 2026 – Reviews & Top Picks

Lysine is often used to treat symptoms commonly caused by feline herpesvirus infections. If your cat is diagnosed with this condition, your vet may prescribe or recommend a lysine supplement. If this is the case for your cat, there are...

cat having treat

How Do Cats Show Sadness? 8 Vet-Verified Ways

Many of us who love cats are drawn to their independent and aloof natures. Compared to their canine counterparts, it can sometimes be a challenge to know what your feline buddy is thinking and feeling. Don’t mistake their chill vibe...

sad looking cat lying on a table

Why Is My Cat Scratching at the Window? 5 Reasons & How To Stop Them

A cat scratching the window can be irritating, especially if it happens constantly during the day or at night when you are trying to sleep. Cats may scratch at windows for a variety of reasons, from wanting to reach prey...

Black and white cat pawing at the window

Love Cats? So Do We! Join the Catster Community

Stay informed with expert pet care insights delivered straight to your inbox! Discover professional guidance on animal behavior, feeding tips, trusted product picks, and much more.




Sign up for the Catster Email Newsletter

Stay informed with expert pet care insights delivered straight to your inbox! Discover professional guidance on animal behavior, feeding tips, trusted product picks, and much more.