Get

In Your Inbox

Catster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

Rabies Vaccines for Cats: A Complete Guide (Vet Answer)

cat getting a shot from a vet

Vaccines are an important way of contributing to your cat’s medical care and ensuring they stay healthy for many years to come. In addition to a yearly or twice-yearly physical exam with their vet, they also need to have their vaccine needs assessed annually.

Vaccines consist of core and non-core vaccines, depending on a cat’s lifestyle—such as if a cat is an indoor vs outdoor cat, how often they might board in a cattery—as well as their age and other risk factors.

Rabies vaccines fit into both categories, depending on where you and your cat live. In some geographic locations, they are considered a core vaccine and are required by local or state laws. In other countries that don’t have rabies virus, rabies vaccines may not be used in pets and are, therefore, not considered a core vaccine. However, if these cats travel overseas to countries with rabies, they may then need to receive their rabies vaccine, often with a very specific timeline in regards to when they are traveling.

Rabies virus is a seldom-encountered disease but is well-known as very serious and uniformly fatal. Rabies is contracted through a bite wound from an infected animal. It is only a short period of having the virus before an animal succumbs to the disease. Because rabies can be transmitted from animals to people, it is considered a “zoonoses.” Rabies occurs rarely but is fatal in humans and animals alike. Therefore, vaccinating your pet for rabies is highly preferable to the alternative.

Read on to learn more about the rabies virus, the disease, the vaccine, and what your cat needs to prevent this fatal disease.

divider 1 paws

What Is Rabies Virus?

Rabies virus traditionally lives in sylvan or woodland animals. It is only found in certain countries, and some island countries, such as Australia, New Zealand, and the United Kingdom, are considered to be rabies-free. This makes importing animals into these countries from countries where rabies is present a bit challenging for pet owners.

The virus travels through the nerves of infected animals, creating the typical nervous system signs that are seen in the infection.

How Do Rabies Vaccines Work?

There are two main forms of rabies vaccines for cats: killed vaccines and vector vaccines. Killed vaccines contain inactive genetic material that can’t reproduce the original virus but still allows the immune system to recognize the pathogen. Vectored or recombinant vaccines are a newer form of rabies vaccines that don’t involve adjuvants to trigger the immune system.

The premise is that, without adjuvants, these vaccines are less likely to cause some of the serious (but rare) side effects seen in traditional vaccines. After receiving a vaccine, the body recognizes the foreign material contained in the vaccine and produces an immune response. This takes about 7–14 days to reach a peak response.

For infectious diseases that cats should not routinely encounter, such as rabies, vaccines are considered effective after a single dose. The body produces antibodies available to recognize the virus in the future, and memory cells that learn the virus are triggered to produce future antibodies against it on short notice.

Veterinarian at vet clinic giving injection to cat
Image Credit: Tom Wang, Shutterstock

What Causes Rabies in Cats?

Rabies in cats is caused when a cat is bitten by an infected animal, such as a raccoon, skunk, or bat. Some carriers of rabies are more common in certain areas of the world. After the bite, the virus travels slowly via the nerves until it infects the nervous system and ultimately causes death. Unfortunately, once infected with rabies, there is no treatment for cats.

Where Are the Signs of Rabies in Cats?

Signs of rabies virus are highly varied and can include:
  • Drooling
  • Biting
  • Water phobia
  • Seizures
  • Lack of appetite
  • Lethargy
  • Hiding or other behavioral changes
  • Weight loss

Because the rabies virus is deadly and transmissible to humans, it is imperative that you contact your vet immediately if you have any concerns about your cat being exposed to or showing signs of rabies.

If you need to speak with a vet but can't get to one, head over to PangoVet. It's an online service where you can talk to a vet online and get the advice you need for your pet — all at an affordable price!

PangoVet_Mention-in-Content for PangoVet2 save money

Traveling with a Cat: How Does the Rabies Vaccine Fit in?

Rabies vaccines are mandatory in some countries within a specific period prior to travel or before issuing a health certificate for travel. Ensure that you know the requirements that are specific to your travel destination.

divider 1 paws

Frequently Asked Questions

What Is a Typical Rabies Virus Vaccine Schedule?

Rabies vaccines are typically given every 1–3 years, depending on the vaccine. Most are licensed for use for cats 12 weeks of age and older.

Veterinarian giving injection to cat
Image Credit: Africa Studio, Shutterstock

Does My Indoor Cat Need a Rabies Vaccine?

Indoor cats are not exempt from contracting rabies, and many areas require that cats be vaccinated regardless of their indoor or outdoor lifestyles. Therefore, it is a good idea that your cat has at least been vaccinated against rabies at some point in their life.

What Are Possible Rabies Vaccine Side Effects?

Common side effects of vaccines in cats include lethargy, followed by vomiting and/or diarrhea. Cats rarely develop anaphylaxis (life-threatening allergic reactions to vaccines), facial swelling, or hives, as many other species are prone to developing. Let your vet know if your cat experiences any reactions to a vaccine, as this may change how they should be vaccinated moving forward.

However, vaccines can also have rare but serious side effects. One of the more serious side effects, particularly in cats, is called vaccine-associated fibrosarcoma, which is a type of cancer that forms from the cells forming the connective tissue layer under the skin. There is strong evidence to suggest that a combination of genetics, along with certain vaccines, has led to the formation of these cancers in cats.

Many of the vaccines are now made differently so as not to contain adjuvants. Additionally, most vaccines in cats are now given in specific locations of the body. That way, if one of these cancers occurs, the vaccine that may have played a role can be identified.

divider 1 paws

Conclusion

Rabies is a serious, fatal disease in cats and humans. Therefore, vaccines are not to be taken lightly. Any healthy cat at risk of being exposed to the disease should receive appropriate rabies vaccines, as determined by their veterinarian.

See Also: 


Featured Image Credit: Kachalkina Veronika, Shutterstock

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything cat

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.

How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Catster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

6 Responses

  1. my vet in ontario only gives the rabis shots for 1 year. I want the 3 year vacine.
    I do not want to take my cat in every year for a rabies shot. i feel it is a money making thing. also have to pay for the appointment for the check up. vets are being taken over by VCR .. a money making company.
    where can i get a 3 year vacine for the cat

    1. Hi Renee Goldstein, sorry to hear about your story, we recommend you look for a second opinion from a different vet in your area, your cat’s lifestyle and risk assessment need to be considered to decide which vaccine is best for them.

  2. i had a stray tom cat neutered. he received a rabies shot. 6 days later he bit me twice – now enflamed.
    HOW LONG DOES IT TAKE A RABIES VACCINE TO BE EFFECTIVE.
    DO I NEED TO HAVE THIS CAT QUARENTINED AND HOW LONG

    1. Hello Martha,
      thank you for your message and sorry for a bit of a late reply. To answer your question – the cat is considered fully immunized after 28 days after the initial vaccination. Through that period, you should look out for your cat and don't let them roam freely outside.
      Please get your MD to see your bites and make him aware of the situation.

  3. Why I’m I being forced by vets to give indoor cats rabies vaccines, if on Long Island we have only one case of rabies since 2016? The rabies vaccine has major side effects including cancer down the road. Raccoon’s are not coming in my house to bite my cats. Is this just a money making scam by vets, I’ve done the research, I’m not seeing why the push to go crazy with vaccines that can and have shortened my cats lives.

    1. Dear Donna,

      Thank you for reaching out. This is a question more pet owners may be asking themselves. Indoor cats are not exempt from getting rabies, though it is less likely. Rabies is a public health problem and thanks to the coordinated efforts of health experts, fewer than 10 human deaths are reported each year in the U.S., down from several hundred before 1960. Rabies is a zoonotic and deadly disease. This means that it is transmitted from animals to humans and that death is inevitable once the symptoms of the disease develop. If medical help is sought immediately after contact with a suspected rabid animal, before the disease develops, there are medical options, called post-exposure prophylaxis (PEP). Here you can read the latest report about Rabies in the U.S., for further information.

      Rabies is such a serious disease that it is the only cat vaccine for which legislation exists and New York state is among the 6 states that account for more than 50% of animal rabies cases in the latest U.S. surveillance.

      If you have any more concerns we have an online veterinary service where you can book a consult and have a video call with one of our experienced vets. Simply go to https://pangovet.com/schedule-appointment/ to book today. Hope that helps!

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.

Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

Do Our Cats Feel Happiness? 5 Signs & Playing Tips

Research shows that cats have systems of emotions that trigger certain emotional and behavioral responses.1 However, the word emotion in this sense refers...

Why Do Cats Stretch When They See You? 5 Common Reasons

Picture this. Walking in your front door after a long, grueling day at work. The house is quiet, but then you hear it...

Persian Kittens for Sale in Australia: 2025 Breeders List

Catster advocates for adopting before shopping, though we fully understand there are many reasons for seeking a breeder. So, we encourage it to...

Hiking With a Cat: If It Is Possible & Vet-Approved Tips

Many cats enjoy spending time in the great outdoors, either on walks or while enjoying catios and other enclosures. Fresh breezes and blue...

More related

How to Tell if My Cat is in Pain: 7 Vet-Reviewed Signs to Look For

Cats are notorious for hiding their illnesses. From an evolutionary standpoint, it makes sense. Cats hide their illnesses to ensure they are not...

Cat Life Stages Explained (Plus 12 Vet-Approved Tips To Improve Their Wellbeing)

It’s not uncommon for cats to live well into their 20s, and certainly into their late teens, largely thanks to improved healthcare and...

10 Best Cat Beds to Put on a Desk in 2025 – Reviews & Top Picks

Cats are notorious for lying in the worst spots, like on top of the computer or right on the keyboard. Whether it’s because...

Open vs. Closed Litter Box: Main Differences, Pros & Cons

Your cat is an important member of your family, so you want everything to be perfect for him, from food to toys and...

Keep reading

How to Remove a Tick From a Cat: Vet-Approved Steps & Advice

Removing a tick from a cat is not difficult, but it may not be as easy as you think. The hardest part is keeping your cat still, but the process is quite simple with a tick removal tool. You must...

removed tick from cat

How to Give a Cat a Head Massage: 4 Vet-Reviewed Tips & Benefits

You wouldn’t think giving a cat a head massage would be something your feline would like, but you would be surprised. While not all cats are receptive to being massaged, for some, it helps them to relax, calm down after...

Cat Massage

Why Is My Cat Gagging? 7 Vet-Reviewed Reasons

If you’ve recently seen your cat gagging, you may wonder what causes it and whether you should be concerned. Gagging is a confusing term, as it can mean different things to different people. Short of boring you with medical definitions,...

tabby white british shorthair cat gagging outdoors

Why Do Cats Lick Themselves After You Pet Them? Deciphering Cat Behavior (Vet-Reviewed)

Cats engage in many behaviors that can leave us scratching our heads and wondering what’s going on. If you’ve found that your cat is doing something you can’t explain, it doesn’t necessarily mean that anything is wrong, though it could...

cat licking itself close up

Do Cats Grieve for Their Owners? A Helpful Guide

Although they may often seem aloof and indifferent, cats recognize the strong bond with their owners. Caring for and connecting with our pets makes us a central facet of their lives and one they’ll sorely miss upon our passing. Cats...

sad, bored or sick cat

6 Homemade Cat Food Recipes for Senior Cats (With Pictures)

We all know that a nutritionally balanced diet made up of high quality ingredients is vital to a long and healthy life. But with so many types of senior cat food on the market, how can you be sure that...

Homemade Cat Food Recipes for Senior Cats

Is Your Cat Vomiting? Try These Gentle Vet-Approved Diet Fixes

Watching your cat throw up is scary, and the wrong food can make things worse. When your feline friend’s stomach is upset, choosing the right diet becomes a delicate balancing act. But don’t worry, with a few smart moves, you...

a cat that feels sick and seems to vomit

How to Spot a Broken Cat Tail: 5 Vet-Reviewed Steps

Cats have very flexible tails, and you may even see them with “kinks” and strange angles. Usually, this doesn’t mean that the cat’s tail is broken. However, cats can certainly break their tails. While a tail may seem like one...

tail of a cat on vintage background