Get

In Your Inbox

Catster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

Manx Syndrome in Cats: Our Vet Explains the Causes, Signs & Treatment  

Manx Cat standing in a black background

The Manx cat is a breed of domestic cat originating on the Isle of Man. Although it’s possible for a Manx cat to have a normal length tail, the breed is best known for being tailless or having a small stub of a tail. While this unique feature sets the breed apart from other cats, it’s also associated with various health issues. Some Manx cats suffer from a range of spinal and neurological defects known as Manx syndrome as a result of their absent or short tails.

divider 3 paws

What Is Manx Syndrome?

Manx syndrome is a collection of health issues seen in Manx cats. While the syndrome is most common in Manx cats, it’s possible for mixed breed cats without tails to be affected.

The syndrome is associated with the Manx breed’s characteristic feature – an absent or shortened tail. The same gene that causes an absent or shortened tail, also causes developmental abnormalities of the spinal cord and the nerves supplying the bladder, colon, hindlimbs, and perineal region. As a result, cats with Manx syndrome have issues with defecation, urination, and hind leg movement. Manx cats with a short tail are also prone to painful arthritis in the joints between the deformed tail bones.

Not all Manx cats develop Manx syndrome, although the likelihood of a cat developing neurological issues is related to how short the tail is. Some Manx cats appear normal, apart from their short tails, and show no signs of spinal cord issues. Others have major abnormalities of the spine and spinal cord and cannot lead normal lives.

female calico manx cat yawning
Image Credit: Karen Sanders Studio, Shutterstock

What Are the Signs of Manx Syndrome in Cats?

The signs of Manx syndrome vary depending on how severely a cat’s spinal cord is affected.

Signs of Manx syndrome include:
  • Absent tail
  • Inability to control the release of urine
  • Secondary urinary tract infections
  • Inability to control the release of feces
  • Constipation due to loss of nerve function
  • Megacolon (distension of the colon)
  • Partial paralysis of the back legs
  • Incoordination of the back legs
  • Lack of sensation of skin around the anus and genitals
  • Rectal prolapse, where some of the rectum protrudes and prolapses through the anus

divider 3 paws

What Are the Causes of Manx Syndrome?

Manx syndrome is caused by a genetic mutation, passed on from parents to their kittens. This genetic mutation causes the abnormal development of the last vertebrae (bones) of the spine that make up the tail.

Fetal Development

While a kitten is still a fetus, the development of the spine is closely linked to the development of the spinal cord. So, if a cat has any developmental abnormalities of the spine (like being tail-less or having a shortened tail), there will often be spinal cord abnormalities present. It is these problems of the spinal cord that cause the neurological issues seen in cats with Manx syndrome. Cats with Manx syndrome can have varying degrees of spinal defects and therefore the severity of the condition can vary.

Adorable tailless Manx cat kitten
Image By: Nynke van Holten, Shutterstock

The Role of Genetics

Tailless-ness in Manx cats is due to a mutant, autosomal dominant gene. “Autosomal” means that the specific gene is located on one of the numbered chromosomes and not on a sex chromosome. The disease is therefore not related to the sex of the cat and both male and female Manx cats can be affected. “Dominant” means that a single copy of the mutated gene (from one parent) is enough to cause the defect. In fact, having two copies of the mutated gene causes such severe problems that kittens usually die before they are born.

The mutant gene does not always “penetrate fully” or show its full effect, therefore different tail lengths are seen.

Varying tail lengths carry different descriptions:
  • Rumpy – no tail
  • Rumpy riser – a bump, or rump of a tail
  • Stumpy – a small, partial tail
  • Stubby – a short tail
  • Tailed or longy – a half-length or normal tail

The likelihood of a cat developing issues is directly related to how short the tail is.

divider 3 paws

What Is the Treatment for Manx Syndrome?

There is unfortunately no curative treatment for Manx syndrome. Instead, treatment is supportive and varies based on the individual cat’s condition.

Treatment may include:
  • Stool softeners to treat constipation
  • Manually emptying the bladder of cats that are unable to control their bladders
  • Antibiotics to treat secondary urinary tract infections
  • Daily grooming for cats incapable of controlling their bowels or bladder.

Some cats are so badly affected that it’s impossible for them to have a good quality of life. In these cases, euthanasia is recommended.

How Do I Care for a Cat With Manx Syndrome?

Daily grooming is essential for cats that can’t control their bowels or bladder. Chronic contact of the skin with urine or feces can lead to urine scald, dermatitis, and infections, so it’s important to keep your cat clean.

You’ll also need to make some changes around the house to help your pet. Make sure that your cat’s food and water bowls are easily accessible, and opt for a low-sided, spacious litter box to accommodate any mobility challenges that your cat may have. Ramps or steps can help your cat access elevated surfaces like beds or couches. If you have slippery floors, it’s worth investing in non-slip rugs to help with grip.

Cats with Manx syndrome should be kept indoors. Cats with mobility issues are more vulnerable to attacks by other cats and dogs. They’re also at greater risk of accidents, such as falling, getting stuck, or being hit by vehicles.

Manx cats should also receive regular veterinary check-ups to monitor their overall health.

manx cat on the windowsill
Image Credit: Jeri Blanc, Shutterstock

divider 3 paws

Frequently Asked Questions

How is Manx syndrome diagnosed?

Although a vet may suspect that a cat has Manx syndrome based on their physical appearance (i.e., an absent or a short tail) and the clinical signs they’re showing, diagnostic tests are necessary to confirm the diagnosis and to exclude other diseases that can look similar.

These tests include:
  • Physical exam including a neurological exam
  • X-rays
  • Magnetic Resonance Imaging (MRI)
  • Myelography to visualize the spinal cord
  • Urinalysis and urine culture

Can Manx syndrome be prevented?

Manx syndrome can be prevented by no longer breeding tailless cats. Some organizations feel that breeding cats without tails, simply for human gratification, is unethical. Cats use their tails for balance and to communicate with other cats. There is no benefit to breeding a cat without a tail, and in some cases, it’s detrimental to the health and wellbeing of the animal because of the associated spinal abnormalities.

divider 3 paws

Conclusion

Manx cats are known for their shortened or absent tails. Unfortunately, this defining feature is linked to a range of spinal and neurological defects known as Manx syndrome. While not all tailless cats are affected, some will develop issues with urination, defecation, and hindlimb movement. These issues range from mild to severe, with the degree of severity depending on how badly the cat’s spinal cord is affected.

While there’s no curative treatment for Manx syndrome, it’s still possible for some of these animals to enjoy a good quality of life with the right care.


Featured Image Credit: slowmotiongli, Shutterstock

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything cat

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.




How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Catster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.


Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

How Does Epogen Help With Kidney Failure in Cats? (Vet Answer)

The kidneys are complex, multifunctional organs. They’re most commonly known for the role that they play in filtering the blood and making urine,...

Abyssinian Cat Breed Info: Pictures, Traits & Facts

The Abyssinian cat, or the Aby, is unique compared to many other fuzzy felines commonly kept as pets. These lovely creatures combine most...

10 Thoughtful Ways to Memorialize Your Cat

Once adopted, a pet cat adapts to the household dynamic. It doesn’t take too long to create an initial bond, and the bond...

Ghost Stories Starring Cats: 6 Spooky Tails

Most people don’t find cats very scary. In fact, they find cats adorable, friendly, and fun. But that is not always the case....

More related

What Is a Digitigrade? Our Vet Explains Cat Locomotion

One of the many ways in which animal species are classified is by their type of locomotion—ie. the way they walk. The three...

Can Cats Eat Vegemite? Vet Reviewed Facts & Advice

Some cats are finicky eaters, while others seem to want to try anything that they can get their paws on! Felines like “meaty”...

Up Close and Purrsonal with Simon Tofield, the Creator of Simon’s Cat

On Sunday, I was lucky enough to be one of only a few local media members to get a private interview with Simon...

How Long Can Cats Go Without Water? Vet-Verified Science & Facts

Cats are notorious for not drinking enough water, to the point that there is an entire industry of pet fountains to entice cats...

Keep reading

Is Rhododendron Toxic to Cats? Vet Approved Facts & Safety Tips

Rhododendrons or azaleas are some of the most popular landscaping plants. It’s easy to see why—they’re gorgeous with their colorful, showy flowers. The genus is large and diverse, with over 1,000 species on four continents1. Of course, there are also...

Catster_Is Rhododendron Toxic to Cats

6 Reasons Your Cat May Attack You & How to Fix It

Your normally happy cat is staring intently outside at something, tail completely straight and ears back. You wonder what is bothering them, so you walk over to your cat and they suddenly lash out at you! Even worse is when...

man playing with cat in bed_Anna Kraynova_shutterstock

How to Help a Grieving Cat: 6 Helpful Tips

Figuring out why your cat acts the way they do can be a complicated matter. We know cats are different from humans, but they can experience some of the same emotions. For example, most animal behavior experts believe cats can...

Sick sad cat lying on the bed

Are Bonsai Trees Poisonous to Cats? Vet-Reviewed Houseplants Examined

The unique and beautiful bonsai tree is grown to give the impression of being a full-sized, mature tree. The question of whether it is poisonous to cats isn’t easy to answer because a bonsai isn’t a species of tree. In...

Catster_Are Bonsai Trees Poisonous to Cats

Is Aglaonema Toxic to Cats? Vet-Verified Houseplant Advice

House plants are a fantastic way to give your home some life, so much so that many people have taken up the role of plant parents, adorning their space with greenery. Aglaonema commutatum, also known as the Chinese evergreen plant,...

Catster_Is Aglaonema Toxic to Cats

Can Cats Control Their Tails? Vet-Verified Positions & Movement Explained

Cats use their tails to communicate to the world through body language. You can tell a lot about a cat’s disposition by what their tail is doing. With that being said, cats have full control of their tails. The tail...

tail of a cat on vintage background

Cat Resource Guarding: Vet-Reviewed Causes & What to Do

When you get a new pet, you hope for the best. You want the cat to fit in with your household and all its members, humans, and other pets. The most common reason for unsuccessful adoptions is behavior, particularly with...

angry cat

How To Tell Which Cat is Dominant? 5 Vet Approved Signs To Look For

Contrary to the aloof and standoffish stereotype that’s been given to cats, cats have a wide range of personalities and temperaments. Some may have the independent personality that they’re known for, but many domesticated cats are very social and love...

two cats playing on a hammock at home

Love Cats? So Do We! Join the Catster Community

Stay informed with expert pet care insights delivered straight to your inbox! Discover professional guidance on animal behavior, feeding tips, trusted product picks, and much more.




Sign up for the Catster Email Newsletter

Stay informed with expert pet care insights delivered straight to your inbox! Discover professional guidance on animal behavior, feeding tips, trusted product picks, and much more.