Get

In Your Inbox

Catster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

E. Coli Infection in Cats: Vet Approved Signs, Causes & Care

Share

sick orange cat

E. coli, or Escherichia coli, is a bacterium that sits in most living mammals’ digestive tracts. It can be found in human and animal urine and feces. It’s usually a commensal organism, part of the normal bacterial flora of the body. However, it can cause life-threatening illness in certain circumstances. E. coli infections in healthy adult cats are pretty rare. But kittens and older cats can develop this infection because their immune systems are not quite as up to par as healthy adult cats. It’s important to note that if your cat is immunocompromised or has health issues, it’ll be easier to develop an E. coli infection.

In this guide, we’ll tell you what E.coli is in cats, the causes, and the signs you should look out for with your feline friend. We’ll also provide tips for caring for a cat with an E. coli infection, so stay tuned.

divider 3 paws

What Is E. Coli in Cats?

E. coli in cats is a bacterium that usually lives in the gastrointestinal tract without causing any problems. There are hundreds of strains of this bacteria, and most of them are harmless to your feline. The problem occurs when E. coli enters parts of the body that it doesn’t belong in or when a harmful strain of the bacteria is introduced through the cat’s system. Lab tests are required to diagnose this infection because the signs vary depending on the strain, location, and the individual cat.

This bacterial infection is more often seen in kittens in the first few weeks after birth. There have been over 700 subtypes of E. coli1 identified so far.

sick cat
Image Credit: sick cat, Flickr

What Are the Signs of E. Coli in Cats?

You’ll need to be on the watch out for a few signs of an E. coli infection in your cat, especially if you have a young kitten or your cat is older. It’s important to note that E. coli can cause different types of illness, which will cause various health signs.

Urinary Tract Infection

  • Urinating outside of the litter box
  • Frequent urination
  • Foul-smelling urine
  • Straining when trying to urinate
  • Fever
  • A tender abdomen
  • Bloody urine
  • Pain when urinating and meowing loudly

Pyometra (Female-uterus infection)

  • Distended abdomen
  • Poor appetite
  • Lethargy
  • Excessive panting
  • Increased thirst
  • Vaginal discharge

Gastrointestinal

  • Vomiting
  • Diarrhea, sometimes bloody
  • Lack of appetite

Colibacillosis (Kittens)

  • Vomiting
  • Lethargy
  • Dehydration
  • Decreased body temp
  • Severe diarrhea
  • Lack of appetite

If you see any of these signs in your cat, it’s best to contact your vet.

If you need to speak with a vet but can't get to one, head over to PangoVet. It's an online service where you can talk to a vet online and get the advice you need for your pet — all at an affordable price!

PangoVet_Mention-in-Content for PangoVet2 save money

divider 3 paws

What Are the Causes of E. Coli in Cats?

E. coli infections are caused by an overgrowth of the bacteria in the animal’s body; each infection that results from an E. coli infection has its own method of transmission. For example, a UTI can be caused by ascending infection- from the outside-in, pathogenic E. coli travels from the external body surface around the anus to the urinary tract, which causes an infection to set in. While this doesn’t usually cause a problem for cats in good health, it could be if your cat is older or has an underlying issue.

Gastrointestinal infections resulting from an E. coli infection could come from your cat’s undercooked or raw food. Therefore, many vets caution against putting your cat on a raw meat diet.

Newborn kittens can end up with the infection in these ways:

  • During birth, when the bacteria is in the birth canal
  • Before they are born
  • While they are nursing
  • When the kitten is living in unsanitary conditions

How Do I Care for a Cat with E. Coli?

Once your pet has been seen by a veterinarian they may send you home with medications to give your cat. Antibiotics are the standard treatment for E. coli in cats, and supportive care is used. Sometimes, intravenous fluids are used as well to restore fluid balance. In cases of newborn kittens with an E. coli infection, aggressive treatment is necessary for their survival.

After treatment, when you get your cat home from the vet, it’s best to give them the space they need to recover. Make sure they have easy access to all resources, such as food, water, and litter trays. Keep a close eye on your pet to ensure they are doing okay, and remember to love and pamper them. Ensure good hygiene to protect yourself and other pets from infection.

tired sick cat lying on bed
Image Credit: Natata, Shutterstock

divider 3 paws

Frequently Asked Questions (FAQ)

How Do I Prevent an E. Coli Infection in My Cat?

As E. coli is found frequently in the environment and inside cats’ bodies it cannot easily be prevented. Ensuring good environmental hygiene, such as cleaning food and water bowls, litter trays, and bedding. Monitor for signs of illness and discuss any concerns with your veterinarian.

What Can I Use to Get Rid of E. Coli in My Home?

E. coli from raw food can hang around the house for up to 28 days. Ensure good hand hygiene practice and disinfect food preparation surfaces regularly. Keep separate cutting boards for raw and cooked meats.

divider 3 paws

Conclusion

E. coli infections in cats can affect different body systems and must be treated effectively and promptly. If you see any of the signs of E. coli infection, contact your vet for an appointment. You can reduce the chances of the bacteria infecting your cat or family by thoroughly cleaning and sanitizing food prep areas, keeping your clean, and scheduling regular visits to your veterinarian.

BF000A


Featured Image Credit: Pixabay

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything cat

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.




How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Catster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.


Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

Ask Dr. Paola – Help! My Male Cat Gets Into Fights! (March 9, 2026)

Welcome to our “Ask Dr. Paola” series, where every Monday we bring expert advice straight from Dr. Paola Cuevas (MVZ) to help our...

Why Your Cat’s Poop Smells Like a Biohazard

Nobody enjoys litter box duty, but sometimes it gets unbearable. The smell hits you from across the room. You’re scooping faster, lighting candles,...

RIP Your Furniture? Not With This Guide to Cat Scratch Damage Control

Your couch looks like it survived a minor apocalypse. The curtains have mysterious vertical shreds. That new rug you splurged on is already...

Celebrating 15 Years as the Most Popular Resident of No. 10 Downing Street

For almost 300 years, a rather unassuming Georgian building of black bricks with a shiny black door has been the official residence and...

More related

Meet Aleister, the Devilishly Dapper Cat of Dita Von Teese

Originally published on 27 October 2016 and republished as a tribute to Aleister Von Teese, the distinguished Devonshire Rex cat. Dita Von Teese...

My Cat Lost a Claw – Do Cat Claws Shed? Vet-Reviewed Facts & Advice

If you’ve found bits of your cat’s claws around the house, the good news is that this is a normal and healthy part...

It’s Crunch Time, Cyril: A Weight Loss Journey (Part 2)

Hi, I’m Dr. Karyn! Read my introduction to learn more about me and meet my five hilarious cats: Clutch, Cyril, Alex, Zelda, and...

Inappropriate Elimination In Cats: Vet-Approved Guide & Explanation

Cats usually are pretty good about going to the bathroom in their litter boxes, but some occasionally veer off course and start peeing...

Keep reading

Why Do Cats Like Milk? 2 Vet-Approved Reasons & FAQ

A cat lapping at a bowl of milk is something that we all think of when it comes to felines. This perception comes from farm cats from bygone eras lapping at the fatty topping of unprocessed cow’s milk and popular...

two cats drinking milk from the same bowl

10 Fascinating Vet-Reviewed Facts About Polydactyl Cats (With Pictures)

Polydactylism is when an animal has a higher-than-usual number of fingers and toes. It is actually surprisingly common in some animals, including cats. While cats usually have five toes on each of their front feet and four toes on their...

cute little paws of a polydactyl cat

Why Do Cats Fall Over in a Harness? Our Vet Explains

Trigger Warning: The study described below includes harm done to cats in a laboratory setting and may be upsetting to some readers. Please proceed with caution. Keeping a cat indoors is proven to increase their lifespan and reduce the risks...

cat with harness sitting in the garden

Are Tulips Toxic to Cats? Vet-Reviewed Safety Information

Tulips are beautiful flowers, so there is no question why they are so popular. They are common inside and outside. Many cut flower bouquets include tulips, for instance. However, tulips are toxic to cats and many other pets. Because flowers...

Catster_Are Tulips Toxic to Cats

Are Rubber Plants Toxic to Cats? Vet-Reviewed Houseplants Examined  

The American rubber plant (Peperomia obtusifolia) is native to South America. However, it will flourish indoors with proper humidity and adequate sunlight. This plant is also called a baby rubber plant and a pepper face plant. Your cat may take...

Catster_Are Rubber Plants Toxic to Cats

7 Best Glucosamine for Cats of 2026 – Reviews & Top Picks

Glucosamine can relieve joint problems in humans, and it can probably do the same thing for your cat. Whether your cat has arthritis or sore joints in old age, this supplement may put some pep back in your cat’s step....

LaPerm tri-colored cat

How Often Should I Change Cat Litter? 5 Things to Consider (Vet-Reviewed)

Cats are fastidious animals that greatly appreciate fresh, clean litter. If the litter isn’t up to their standards, they may just do their business somewhere else—like your floor, which is why it’s important to keep up with litter box maintenance....

man-cleaning-litter-box

What Do Cats Think About All Day? Facts & FAQ

Your cat is sitting in their favorite spot, staring into the distance. They look just like they’re contemplating the mysteries of the universe—but are they? Figuring out what cats think about all day isn’t an easy task. There aren’t very...

ragdoll cat lying on couch

Love Cats? So Do We! Join the Catster Community

Stay informed with expert pet care insights delivered straight to your inbox! Discover professional guidance on animal behavior, feeding tips, trusted product picks, and much more.




Sign up for the Catster Email Newsletter

Stay informed with expert pet care insights delivered straight to your inbox! Discover professional guidance on animal behavior, feeding tips, trusted product picks, and much more.