Get

In Your Inbox

Catster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

How to Keep a Clean House With Multiple Cats: 9 Vet-Approved Cleaning Tips for a Spotless Home

multiple cats

Living with multiple cats can be fun, especially if all your cats are pals and get along. However, the assumption that the home must stink to high heaven is usually at the forefront when one thinks of a home with multiple cats. Litter boxes don’t smell like daisies and are typically the culprit to odors in the home, and most cats shed, adding more mess. To add insult to injury, so to speak, when you have multiple cats, you need multiple cat boxes, and you must also keep cat hair down so you don’t have cat hair tumbleweeds flowing around.

So, how do you keep a clean house with multiple cats? Join us in learning nine tips for how to keep a clean house so you’re not viewed as the nutty cat lady with a stinky home that no one wants to visit.

divider 2 cats

divider 3 paws

How to Effectively Clean Up Cat Messes, Odors & Stains 

The first part of cat mess prevention is ensuring you are taking the time to properly clean any accidents -  and that starts with investing in the right products! Of course, you'll want to opt for something safe first and foremost, to protect your feline's health, but secondly, you'll need a solution powerful enough to lift the toughest, stinkiest, most set-in stains. After careful consideration, we fell in love with one product and highly recommend it to all pet owners! 

Our Favorite Enzyme Cleaner 

Image Product Details
Best Enzyme Spray
Winner
Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray
  • All-purpose
  • Pet-safe
  • Multi-surface safe
  • There are several reasons we can't get enough of the Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray.  It permanently removes the very worst smells and stains, it can be used on a multitude of surfaces and its neutral scented, meaning no odor masking! It comes in a generous 32-oz bottle and comes with 100% satisfaction guarantee. Learn more about this holy grail of a cleaner here!

    At Catster, we’ve admired Hepper for many years, and decided to take a controlling ownership interest so that we could benefit from the outstanding products of this cool cat company!

    A rule of thumb when owning multiple cats is to have the correct number of litter boxes. So, you need a litter box per cat, plus one extra. For example, if you have three cats, you need four litter boxes. It sounds like a lot, but if you don’t have the correct number of litter boxes, you’ll end up with urine and feces issues throughout the home, which leads to odor problems.

    Unlike dogs, cats are not pack animals, preferring privacy and space while going potty. So, before we begin, ensure you have enough litter boxes for all your kitties.

    divider 3 paws

    The 9 Cleaning Tips To Keep a Clean House With Multiple Cats

    Now that we know the number of litter boxes you need, we can proceed with how to keep your house clean with multiple cats. Read on to learn nine tips for a spotless home with your beloved felines.

    1. Carpets Equal Odors

    If you have carpet in your home, you may want to consider removing it and replacing it with hard flooring. Carpets trap all sorts of odors, regardless of how much you vacuum. Laminate or hardwood flooring is an excellent choice when you have multiple cats and is easier to clean. Also, if one of your cats eliminates elsewhere, you can clean the spot much more quickly and efficiently, leaving the spot odor and stain-free.


    2. Invest in a Pet Vacuum

    Not all vacuums operate the same, and when you have multiple cats, investing in a quality pet vacuum can help tremendously. Pet vacuums are designed to target loose pet hair and the dander left behind by way of a HEPA filter, which is also excellent for allergy sufferers. They typically come with attachments for accessing hard-to-reach areas, and they have powerful suction. Look for one that works well for all floor types for the best results, and ensure you vacuum regularly—at least once a week.

    Investing in a high-quality pet vacuum is especially ideal if you have carpet and it’s not within your budget to replace it with hard flooring.


    3. Keep a “Cat Room”

    If you have the space, keeping cat toys, bedding, scratching posts, food, water, and litter boxes in a designated room can help keep odors down in other areas of your home. However, you may not have the extra space, and litter boxes should technically be scattered in low-traffic areas of your home. For example, cats desire privacy when they go potty, and keeping the litter boxes in one room is not ideal. This may work for two cats, but if you have more than three cats, you may run into issues, such as one of your cats going potty outside the litter box.

    If you have a well-ventilated sunroom or screened-in patio that’s cat-proof, those areas are excellent choices for keeping one or two litter boxes. The idea is to keep all litter boxes out of the main living areas to keep smells down.

    multiple cats eating from a bowl at home
    Image Credit: Irina Kozorog, Shutterstock

    4. Scoop and Clean the Litter Boxes Regularly

    Clumping clay litter is a popular choice among cat owners because the waste will clump up, allowing you to scoop the waste out and replace it with fresh litter in that spot. You should also clean all litter boxes at least once a week with a mild, pet-friendly detergent and warm water. Ensure you rinse the detergent out completely and dry thoroughly before adding fresh litter.

    Tip: Choose unscented cat litter to help minimize odors and avoid respiratory issues. Scented litter tends to trigger respiratory issues in susceptible cats and humans, and it’s also unsuitable for allergy sufferers in the home. We recommend choosing a low-dust cat litter for this purpose.

    cat outside the litter box
    Image Credit by: Jennifer McCallum, Shutterstock

    5. Use a Cat Litter Mat

    Some cat litter tracks all over the home when your cat exits the litter box, as it gets stuck on the paws and ends up on your floor. You can buy a cat litter mat to help keep this problem to a minimum. Some cat litter is marketed as “low tracking,” and they are worth a try. If your cat is a litter thrower, investing in a litter mat is an excellent option to reduce the mess.


    6. Run HEPA Air Purifiers

    HEPA air purifiers with activated carbon filters can help reduce cat odor; they also help keep dander and dust to a minimum, which is ideal for those with allergies. HEPA (high-efficiency particulate air) filters remove 99.97% of dust, pollen, mold, bacteria, and other airborne particles for a cleaner environment, and they are highly recommended if you live with cats.


    7. Brush Your Cats Often

    Unless you own hairless cats, such as the Sphynx or Peterbald, your cat will shed hair—often. Whether your cats are long- or short-haired, brushing their coats regularly will help reduce loose hair that gets trapped on furniture, clothing, bedding, or any other areas of your home.

    If you own long-haired cats, brushing the coat daily is essential in keeping mats down, which can make cats very uncomfortable. Daily brushing also helps reduce the amount of hair long-haired cats swallow, therefore reducing hairballs. For short-haired cats, you should brush them approximately once a week.

    person brushing a balinese cat
    Image Credit: BravissimoS, Shutterstock

    8. Choose Washable Fabrics

    All cat owners know that cats love to lounge, and choosing machine-washable fabrics helps reduce hair and odors; they also help protect your furniture. When a cover, comforter, cat bed, or any other fabric gets dirty with excessive hair and other particles, it makes a world of difference to throw the materials in the washing machine, as they will come out hair and odor-free.

    Tip: Be careful with the type of laundry detergent you use, as some cats may be sensitive to dyes, chemicals, and fragrances. It’s best to opt for all-natural, pet-friendly laundry detergents without these added ingredients to ensure your cat doesn’t suffer a possible allergic reaction, especially if one of your cats already has respiratory issues.


    9. Keep Enzymatic Cleaners Handy

    Enzymatic cleaners are life savers when you live with pets. Accidents will happen, whether feces, urine, or even vomit. It’s best to tackle the mess right away to help reduce smells and stains, and if you have an enzymatic cleaner at the ready, you’re a step ahead of the game. Enzymatic cleaners contain enzymes that break down bacteria and ammonia in cat urine, which is the culprit for the strong odor.

    Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray
    • ADVANCED ENZYMATIC CLEANER - Penetrates the most stubborn smells and stains at the deepest molecular...
    • FOR ANY MESS, ON ANY SURFACE - This pet odor eliminator cleans your carpets, floors, furniture,...
    • FRESH, NATURAL ODOR - Our unique formulation doesn't rely on dangerous or unpleasant chemical...

    At Catster, we’ve admired Hepper for many years and decided to take a controlling ownership interest so that we could benefit from the outstanding products of this cool cat company!

    divider 1 paws

    Conclusion

    Keeping a clean house with multiple cats requires investing in specific items, such as a pet vacuum with a HEPA filter, running HEPA air purifiers, having multiple litter boxes, keeping the litter boxes clean, brushing your cats, cleaning accidents with enzymatic cleaners, and washing fabrics your cats like to lay on. Although switching out carpet to hard flooring is advisable, not everyone has this in their budget. In that case, ensure you often vacuum with a pet vacuum that targets dust, dander, and hair, and keep those litter boxes clean as much as possible.


    Featured Image Credit: Mustafa ezz, Pexels

    Want content like this delivered to you?

    Sign Up For Our Newsletter

    News, insights, expert advice, and everything cat

    * By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.

    How useful was this post?

    Click on a star to rate (you can leave written feedback after clicking submit)

    Help us improve Catster for pet parents!

    Your feedback really matters.

    What did you like about this post? Also how can we improve it?

    Join the conversation

    Leave a Reply

    You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.

    Talk With A Vet Online

    Peace of mind,
    anywhere, anytime

    Affordable vet advice

    Can Cats Eat Deli Meat (Lunch Meat)? Vet-Verified Facts & FAQ

    If you’ve ever looked up from a leisurely lunch to find your cat eyeballing your meal, you know our feline friends can give...

    5 Best Cat Litters for Declawed Cats in 2025 – Reviews & Top Picks

    Catster does not support declawing. Instead, regularly trim their claws, and provide them with a scratcher to allow your cat to display the...

    Is Catnip Bad for Cats? Vet-Verified Facts to Know

    If you have seen your cat go crazy for catnip and act as if they are “high” and you want to know if...

    Why Doesn’t My Cat Like To Be Held Or Picked Up? 6 Vet-Reviewed Reasons

    No two cats are the same. Just because you’ve owned one in the past or have known somebody else who has owned a...

    More related

    How to Prepare Your House for Someone Allergic to Cats: 7 Easy Ways to Prep Your House

    You may think that living with a cat will prevent all people with cat allergies from visiting your home. While there are cases...

    Zen Clipper Cat Nail Trimmer (2025 Review)

    Review Summary Nail trimming is an essential part of cat ownership to keep your kitty’s nails in tip-top shape while also protecting your...

    10 Best Cat Subscription Boxes in 2025 – Reviews & Top Picks

    Keeping your cat happy and entertained can be a challenge. Pet stores are often stocked with the same toys and treats, so it...

    Can a Cat Recover From Kidney Failure? Our Vet Explains the Signs, Recovery & Diagnosis

    Kidney, or renal failure, in cats is a very common condition. Most cats will suffer from chronic kidney failure, which means that, over...

    Keep reading

    Why Do Cats Blink Slowly? Vet-Verified Behavioral Cues

    One of the best things that you can do for your cat, other than feeding, brushing, and petting them, is to understand them. That is what will set you apart from other cat owners. If you can learn to understand...

    chimera cat with green eyes

    How to Identify and Stop Food Aggression in Cats: Vet-Reviewed Advice

    Cats are in touch with their wild side. You’ll see examples in their behavior, which may seem inappropriate in the home setting, but served them well at a different time. Survival is the primary motivator for most instinctive behaviors, which...

    siamese cat eating food from bowl at home

    My Cat Lost a Claw – Do Cat Claws Shed? Vet-Reviewed Facts & Advice

    If you’ve found bits of your cat’s claws around the house, the good news is that this is a normal and healthy part of owning a cat. As cat claws grow out from the blood supply (also known as the...

    cat paws and sharps claws

    MRI For Cats: Our Vet Explains What Is It, Uses & Costs

    Magnetic Resonance Imaging (MRI) is a form of advanced diagnostic imaging that generates clear 3-D pictures of the soft tissues in the body. If you want more information about your cat’s central nervous system, ears, nose and other soft tissues,...

    vet checking up tabby cat

    10 Best Low-Carb Cat Foods of 2025 – Reviews & Top Picks

    Dry cat foods commonly have hidden carbohydrates in them, including grains, that are used as fillers to bulk the food up. Because cats are carnivores, they only require a small amount of carbs in their diet, and too much can...

    side view of tabby cat eating pet food from feeding bowl on white background with copy space

    Can Cats Eat Oatmeal? Vet-Reviewed Facts & Considerations

    There are few staple breakfast foods that keep you satisfied and full of energy like oatmeal does. But just because it’s good for us doesn’t mean oatmeal is good for cats. So, can cats eat oatmeal? Oatmeal is technically safe...

    Can Cats Eat Oatmeal

    Will a Cat Only Purr for Humans? Do They Do it for Other Cats?

    You may have heard that cats only purr for humans. Well, how true is that? As adorable of a sentiment as it is, cats do not purr for humans exclusively. Cats have been observed purring for other cats and even...

    british shorthair cat yawning and purring

    Can Cats Eat Veggie Straws? Vet-Verified Facts & FAQ

    Human treats are not known for being “healthy”. The average potato chip is mostly fat, oil, and salt, with artificial additives and flavorings and zero nutritional value. Enter: Veggie Straws, a crispy vegetable snack (shaped like a short straw) that...

    Can Cats Eat Veggie Straws