Get

In Your Inbox

Catster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

Shots For Unvaccinated Cats & Older Kittens: 2026 Guide (Vet Answer)

Share

vet holding cat for vaccination

Cats require vaccinations to help protect them from common infectious diseases. Determining which vaccinations your cat may need can be stressful. In this article, we will discuss vaccinations available to our feline companions and recommended vaccine protocols. The American Animal Hospital Association1 and American Association of Feline Practitioners have developed guidelines often followed in the United States.2 It is important to note that vaccination requirements may vary based on your country, disease prevalence, and your pet’s lifestyle so always contact a veterinarian for their specific recommendations.

divider cat paws 2 oct 2024

The 5 Common Shots for Unvaccinated Cats and Older Kittens

1. Rabies

The rabies vaccination is required by law in many states and is considered a core vaccination. Kittens typically receive this vaccination between 12–16 weeks of age, but the age of vaccination is dependent on state laws and manufacturer guidelines.

After the initial vaccination is administered to a kitten or a cat with an unknown vaccine history, another rabies shot should be administered 1 year later. After this next vaccination, the rabies will need to be given every 1–3 years, depending on local law and the type of vaccination administered. Wildlife can serve as a potential reservoir for this virus, and once contracted, the disease is fatal.

cat-having-a-vaccine
Image Credit: Africa Studio, Shutterstock

2. FVRCP (Feline Distemper, FRCP, FVRCPP)

This combination of vaccinations helps protect cats against several different viral respiratory and gastrointestinal pathogens and is considered a core vaccination. The vaccination offers protection against feline viral rhinotracheitis (herpes), calicivirus, and panleukopenia (parvovirus). It is initially given in a series to kittens.

The vaccination can be given starting at 6 weeks and is then boosted every 3–4 weeks until the kitten is over 16 weeks of age. In adult cats without a history of vaccination, the vaccination is administered in a two-part series given close to 3 weeks apart. After the completion of the initial series, a kitten can receive an additional vaccine at 6 months, or at 1 year of age. Further vaccinations are administered every 1–3 years, depending on the vaccine type.


3. Feline Leukemia

Feline leukemia is a highly contagious virus that can cause immune suppression and cancer in affected cats. This vaccine is considered a core vaccine in kittens but is considered a non-core vaccine in adult cats, depending on their lifestyle.

This virus is most common in outdoor cats that have close interactions with other cats. It is also administered in a two-part series and then boosted 1 year later. This can be given to cats as young as 8 weeks of age. For cats that are going to have access to the outdoors or live in an environment where there is the risk of exposure to the virus, the vaccination can be continued. The frequency of revaccination will depend on the risk of exposure and the type of vaccine administered.

cat vaccination
Image Credit: YULIYA Shustik, Shutterstock

4. Feline Chlamydophila Disease

A vaccination against the bacterial agent Chlamydophila felis is available for cats with a high likelihood of illness. This bacterial pathogen can cause conjunctivitis and rhinitis, typically in young cats. The vaccination can be administered to kittens or adults without a vaccination history and should be administered according to the product label. This is considered a non-core vaccination and is only used in environments in which infection with chlamydia has been confirmed.


5. Bordetella

An uncommon, non-core vaccination available to cats is the Bordetella vaccination. Bordetella is an upper respiratory pathogen that can be spread amongst cats. The vaccination doesn’t offer complete protection but may be beneficial in environments where Bordetella has been confirmed. This attenuated live vaccination is given intranasally and should be administered according to the product label.

cat vaccination
Image Credit: YULIYA Shustik, Shutterstock

divider cat paws 2 oct 2024

Side Effects of Vaccinations

Following vaccination, cats may experience soreness, fever, and lethargy. On occasion, localized swelling may be noted. It is encouraged that reactions that occur following vaccination administration be reported to a veterinarian. In some situations, more serious hypersensitivity reactions may occur including anaphylaxis.

Injection site sarcomas can occur because of inflammation following injection. Fortunately, this is not a common occurrence since non-adjuvanted vaccinations have become more readily utilized. Sarcoma formation is still a possibility, and as a result, most veterinarians will administer vaccinations in a location that can allow for surgical removal if a sarcoma were to develop.

If you are concerned or have questions about your cat’s health, you can also speak to a vet from the comfort of your own home to help make a plan. They can determine when an in-clinic vet visit should be made.

Important Notes

It is critical to note that there are several different ways a vaccine is structured. For example, cat vaccines can be inactivated, recombinant, or attenuated live. Additionally, the routes of administration can also vary. As a result, vaccination protocols may differ depending on the product used. It is important to speak directly with a veterinarian regarding the vaccinations that they carry and their recommended dosing protocols.

divider cat paws 2 oct 2024

Conclusion

Vaccinations are at the core of preventative care. A veterinarian will be able to help guide you as to which vaccinations your cat should receive. This will be determined by the age of your cat and your cat’s lifestyle. It is imperative to note that no vaccination can offer 100% protection against illness; however, vaccinations can significantly reduce signs of illness.


Featured Image Credit: bmf.foto.de, Shutterstock

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything cat

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.




How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Catster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.


Catster's Digital Magazine is Back!

Vet-approved health & behavior advice

Real cat stories & community features

Chatting About the Importance of Spaying/Neutering, Cat Retail Shopping Ban & Red-Level Storms | Chatty Cattys, Episode 30

In this episode of Catster’s Chatty Cattys podcast, Nicole and Dr. Karyn are celebrating a major legal win for pets before diving into...

Is Your Cat Happy? Here’s How You Can Tell

Cats have a reputation for being indifferent, even inscrutable. But despite their seemingly ambivalent appearance, cats experience many emotions, including happiness, and they...

Human Brains Age Like Cats – New Study Debunks the 7-Year Rule

If you’ve ever caught your senior cat staring blankly at a wall, wandering the halls at 3 am, calling out for no clear...

Chatting with Devin About Here! Have a Kitten, Fostering, & Why Two Are Better Than One | Chatty Cattys, Episode 29

In this episode of Catster’s Chatty Cattys podcast, Nicole & Dr. Karyn sit down with Devin, the founder and one-woman show behind “Here...

More related

Brown Munchkin Cat: Info, Pictures, Origin & Facts

The Munchkin Cat was first intentionally bred in Louisiana, USA, in 1980, although domestic cats with short legs have likely been around for...

How to Keep a Cat From Jumping Over a Gate: 8 Vet-Verified Tips

We love our cats, and their safety is our number one concern. Sometimes, it may feel like we care more about their safety...

How to Stop Your Cat From Climbing the Curtains: 11 Vet-Reviewed Ways

Cats can get up to all kinds of mischief around our homes—not out of spite but because they’re trying to release pent-up energy,...

How Long Do Cats Mourn the Loss of Another Cat? Feline Grieving Explained (Vet-Verified Info)

Humans are not the only beings that experience emotions. Not only can our cats experience a broad spectrum of emotions that humans share,...

Keep reading

How Old Do Cats Have to Be to Get Pregnant? Vet-Reviewed Science & Facts

A cat’s fertility and reproduction remain unrivalled as kittens grow into sexual maturity sooner than you might expect – as young as 4 to 6 months – meaning your cat can get pregnant as early as four months! For this...

Pregnant cat laying on a staircase

6 Great Activities for Cats at the Beach & Vet-Reviewed Tips (With Pictures)

If you’re planning on taking a vacation or day trip to the beach, the idea of leaving your cat behind is difficult. While dogs are considered man’s best friend, that doesn’t mean our kitty cats aren’t as important. In fact,...

cat walking on the beach

7 Best Calming Aids for Cats in 2026 – Reviews & Top Picks

Cats can benefit from calming aids for a variety of reasons. If you have a cat that is particularly nervous, overly energetic, stressed, or frightened from external factors such as thunderstorms, then using a calming aid for your cat can...

9 Best Cat Meal Toppers in 2026 – Reviews & Top Picks

Disclaimer: Before changing your cat’s food or offering new ingredients, consult with your veterinarian. Pets that are on a prescription diet or suffer from certain ailments may need to avoid certain food ingredients.Caring for a cat certainly has its ups...

Grey domestic cat being given food in a bowl

Why Do Cats Hiss? 5 Vet-Reviewed Reasons for This Behavior

Everyone has heard a cat hiss at least once or twice in their lifetime. Cats are well known for hissing, but it can be confusing as to why a cat might be hissing at any given time. So, why do...

a tabby mackerel cat hissing

8 Common Types of Cat Brushes (With Pictures)

Cats are known for their fondness for grooming and keeping themselves clean, but there are times we cat parents need to lend them a helping hand. No matter how fastidious your favorite feline is, they won’t always be able to...

brushing a ragdoll cat

Scottish Fold Cat Health Problems: 7 Vet-Reviewed Issues

Scottish Fold cats have found their way into many pet lovers’ hearts with their unique folded ears and sweet personalities. As with any breed of cat, the Scottish Fold cat has its own set of health issues you need to...

Catster_Health Problems of Scottish Fold

Does Hot Water Kill Fleas on Cats? Vet-Approved Facts & FAQ

Having a cat in your life is wonderful, but it sometimes comes with a catch: dealing with fleas. Apart from being annoying, flea infestations can trigger allergies, irritation, and even illness. So, getting rid of them as quickly as possible...

woman bathing her cat

Love Cats? So Do We! Join the Catster Community

Stay informed with expert pet care insights delivered straight to your inbox! Discover professional guidance on animal behavior, feeding tips, trusted product picks, and much more.




Sign up for the Catster Email Newsletter

Stay informed with expert pet care insights delivered straight to your inbox! Discover professional guidance on animal behavior, feeding tips, trusted product picks, and much more.