Get

In Your Inbox

Catster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

Feline Distemper: Signs, Causes, and Care (Vet Answer)

Share

sad, bored or sick cat

Distemper in cats is also called feline panleukopenia, so we will use the terms interchangeably in this article. It is a viral disease that can be deadly, especially in kittens.

Vaccines help control it in many countries, but there have been large outbreaks even in vaccinated countries. The vaccine is considered one of the core vaccines because the disease is so contagious. Both indoor and outdoor cats should be vaccinated. Read on below to find out more.

divider 3 paws

What Is Distemper?

Feline panleukopenia virus is highly contagious and can progress to severe illnesses in as little as 1–2 days. It can be deadly and may require intensive hospitalization. It mostly infects kittens and also affects them the most severely.

Infected kittens progress from lethargic and depressed to severely dehydrated and sick fairly quickly. The goal of veterinary treatment is to treat the signs of the illness while the body does its work to fight off viral infection.

charcoal bengal kitten lying
Image Credit: Smile19, Shutterstock

What Are the Signs of Distemper?

  • Lethargy
  • Inappetence
  • Hypersalivation (nausea)
  • Vomiting
  • Diarrhea
  • Sudden death

It is difficult to know if a cat has a fever at home, but the vet will usually confirm a high fever as well. Cats will also become dehydrated quickly but do not drink very much despite needing to.

Is your cat presenting any of these signs? We suggest you speak with a vet online.

If you need to speak with a vet but can't get to one, head over to PangoVet. It's an online service where you can talk to a vet online and get the advice you need for your pet — all at an affordable price!

Preventative wellness PGV mention keep cat healthy Preventative wellness PGV mention keep cat healthy mobile

What Are the Causes of Distemper?

The panleukopenia virus infects dividing or multiplying cells. So, it mostly affects body systems with cells that multiply quickly. This often includes the immune system and the lining of the GI tract in particular. As a result, cats can be immunocompromised—their immune system will not work as well because the white blood cells have all been infected.

They may also experience vomiting and diarrhea because the lining of their digestive tract is compromised. Because the virus impedes the immune system, kittens are often susceptible to secondary infections, so they can easily be infected with other viruses or bacteria.

siamese kitten in a basket
Image Credit: Esin Deniz, Shutterstock

How Do Cats Catch It?

The virus lives in the environment for long periods of time. So, a cat can be directly exposed cat-to-cat or can pick it up in the environment. For example, a cat can pick it up off the sidewalk after a cat with distemper has pooped there—even months later.

How Do I Care for a Cat With Distemper

The disease can be deadly and will usually require hospitalized care for kittens to survive. By providing intensive supportive therapy the body will hopefully have a chance to fight off the infection. All cats with distemper will need to be isolated in a veterinary hospital.

Cats will need intensive treatment and ICU care. This will possibly include but is not limited to:

  • IV fluid therapy
  • Medication
  • Pain management
  • Nutritional support
  • Fever management
  • Antibiotics (in some cases)
cat treated in vet clinic
Image Credit: Raihana Asral, Shutterstock

divider 3 paws

Frequently Asked Questions (FAQ)

When Should Kittens Receive Their Vaccination?

The panleukopenia vaccine is considered one of the main core vaccines for kittens. The vaccine will need to be boosted one month apart for both adults and kittens. Kittens should start receiving their vaccine as young as 6–8 weeks old. Bring your kitten back for boosters once every 3–4 weeks until they are old enough.

If you are unsure of how old your kitten is, still bring it in for a vaccine and discuss the situation with your vet. Once fully vaccinated, your cat will need a booster once a year or once every 3 years, depending on the vaccine brand.

Veterinarian giving injection to cat
Image Credit: Africa Studio, Shutterstock

How Would an Indoor Cat Catch Distemper?

The feline panleukopenia virus is very resistant and can survive for long periods in many environments. It is even resistant to many disinfectants. So, it can easily be picked up on your shoes or clothing and brought indoors to your cat.

Are There Other Diseases with Similar Signs?

Many diseases start with lethargy as the first sign and progress to dehydration and GI signs. So, it will be important for a veterinarian to confirm the diagnosis of panleukopenia while also providing medical support. Some other possibilities could include:

How Is Distemper Diagnosed?

A vet will correlate the signs of distemper, including dehydration and fever, with changes in the blood. Because the immune system is infected the white blood cell count will be low. There is also a PCR or antigen test that can be performed on the feces to confirm an infection.

cat examined by Vets
Image Credit: Kzenon, Shutterstock

divider 3 paws

Conclusion

The most important thing to remember about distemper in cats is that it’s very contagious, and all kittens, indoors and outdoors, should be vaccinated against it. It is a severe illness that often requires your kitten to stay in the hospital for days, and it’s very possible that your kitten may not survive. This is why vaccination is so vital, as well as recognizing the signs and acting quickly if you suspect infection.


Featured Image Credit: Kginger, Shutterstock

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything cat

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.




How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Catster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.


Catster's Digital Magazine is Back!

Vet-approved health & behavior advice

Real cat stories & community features

Vets Urge Owners: Don’t Ignore Sweet Smell Coming From Cats

Cats are not particularly known for having a pleasant aroma. The occasional whiff of fishy cat breath and that unmistakable post-litter-box scent simply...

“A Cat Spay Costs How Much???”

America has a kitten problem. Every day, thousands of cats and kittens are abandoned, surrendered, or discarded. Those who are lucky enough to...

Ask Dr. Paola – Help! My Cat Is Seeking My Attention! (June 15, 2026)

Welcome to our “Ask Dr. Paola” series, where every Monday we bring expert advice straight from Dr. Paola Cuevas (MVZ) to help our...

Everything I Need to Know About Cartoon Comedy, I Learned From My Pets

If you’ve ever looked at your cat doing something ridiculous and thought, “There has to be a joke in that somewhere,” Scott Metzger...

More related

My Cat Ate a Fly: Vet-Verified Dangers & Tips

Cats will chase after and pounce on anything that moves, including small insects. Grasshoppers and flies are popular targets, and they flutter and...

We Chat With Pet Portrait Artist Thomas Dalsgaard Clausen

Pet portraits and artists are prevalent online, but rarely will you find someone who captures the essence of the animals he draws like...

Ear Polyps in Cats: Causes, Signs & Care (Vet Answer)

Ever wonder what a cat is thinking? Quite often, their ears can give us a great deal of information about what is going...

How to Cat-Proof a Fish Tank: 7 Tips & Tricks

Cats are drawn to quick, darting movements, and the colorful fish in the tank in your living room never fail to awaken their...

Keep reading

Can Cats Eat Baked Beans? Vet-Reviewed Risks & Alternatives

Some kitties are notoriously fussy eaters and others will eat anything in sight. For the latter, almost any food can be tempting, including a warm, delicious bowl of freshly baked beans. But while some human foods are safe for our...

Can Cats Eat Baked Beans

15 Hazards That Could Hurt or Kill Your Cat & How to Avoid Them (Vet Reviewed)

When you are at home relaxing with your cat, you might be totally oblivious to all the hazards around the home. After all, we don’t foresee some events, making it difficult to navigate. While we could go on for hours...

vet wrapping cat's injured paw with bandage

Can Cats Drink Gatorade? Vet Approved Nutritional Facts & FAQ

If you have a cat that needs help rehydrating, Gatorade might be the first idea to come to mind. You’re not the only person to get this idea. Many cat owners have tried offering Gatorade to their kitties as a...

Can Cats Drink Gatorade

My Cat Won’t Eat: Causes, Feeding Recomendations & When To Worry (Vet-Verified)

Cats are pretty good at hiding it when they aren’t feeling well, and a sudden lack of interest in eating is a cause for concern. Cats can go off their food for many reasons, from stress to dental pain and...

Tabby cat eating food from white bowl

Can Cats Drink Lactose-Free Milk? Vet-Verified Nutrition Facts

The image of the happy cat lapping up milk is an old cliché. While many feline parents assume that their kitties would enjoy a bowl of milk now and then, the surprising truth is that dairy products from cows could...

Can Cats Drink Lactose-Free Milk

Why Does My Cat’s Breath Stink? 9 Vet Reviewed Reasons & Solutions

If your cat’s breath seems to stink when you lift them up for a cuddle, there can be a few reasons. A healthy cat’s breath shouldn’t smell unpleasant, so if you find yourself wincing when you smell your cat’s breath,...

man holding cat with bad smell

Do Munchkin Cats Get Along With Dogs? Vet-Reviewed Answer & Explanation

Affectionately known as the Dachshund of the feline world, the diminutive Munchkin Cat is pure, fur-covered cuteness! Their loveable looks are mirrored by equally loveable personalities and they are known for being amiable felines that fit in comfortably with most...

Dogs and Munchkins Get Along

How Long Can Cats Go Without Food? Vet-Verified Dangers & Tips

Cats are often hungry little monsters devouring their food rapidly. Conversely, they may be picky eaters that refuse to eat anything but their favorites! In either case, if your cat stops eating, this is a cause for concern. Cats are...

well-fed-cat-looking-for-food-and-not-eat

Love Cats? So Do We! Join the Catster Community

Stay informed with expert pet care insights delivered straight to your inbox! Discover professional guidance on animal behavior, feeding tips, trusted product picks, and much more.




Sign up for the Catster Email Newsletter

Stay informed with expert pet care insights delivered straight to your inbox! Discover professional guidance on animal behavior, feeding tips, trusted product picks, and much more.