Get

In Your Inbox

Catster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

Feline Distemper: Signs, Causes, and Care (Vet Answer)

sad, bored or sick cat

Distemper in cats is also called feline panleukopenia, so we will use the terms interchangeably in this article. It is a viral disease that can be deadly, especially in kittens.

Vaccines help control it in many countries, but there have been large outbreaks even in vaccinated countries. The vaccine is considered one of the core vaccines because the disease is so contagious. Both indoor and outdoor cats should be vaccinated. Read on below to find out more.

divider 3 paws

What Is Distemper?

Feline panleukopenia virus is highly contagious and can progress to severe illnesses in as little as 1–2 days. It can be deadly and may require intensive hospitalization. It mostly infects kittens and also affects them the most severely.

Infected kittens progress from lethargic and depressed to severely dehydrated and sick fairly quickly. The goal of veterinary treatment is to treat the signs of the illness while the body does its work to fight off viral infection.

charcoal bengal kitten lying
Image Credit: Smile19, Shutterstock

What Are the Signs of Distemper?

  • Lethargy
  • Inappetence
  • Hypersalivation (nausea)
  • Vomiting
  • Diarrhea
  • Sudden death

It is difficult to know if a cat has a fever at home, but the vet will usually confirm a high fever as well. Cats will also become dehydrated quickly but do not drink very much despite needing to.

Is your cat presenting any of these signs? We suggest you speak with a vet online.

If you need to speak with a vet but can't get to one, head over to PangoVet. It's an online service where you can talk to a vet online and get the advice you need for your pet — all at an affordable price!

PangoVet_Mention-in-Content for PangoVet2 save money

What Are the Causes of Distemper?

The panleukopenia virus infects dividing or multiplying cells. So, it mostly affects body systems with cells that multiply quickly. This often includes the immune system and the lining of the GI tract in particular. As a result, cats can be immunocompromised—their immune system will not work as well because the white blood cells have all been infected.

They may also experience vomiting and diarrhea because the lining of their digestive tract is compromised. Because the virus impedes the immune system, kittens are often susceptible to secondary infections, so they can easily be infected with other viruses or bacteria.

siamese kitten in a basket
Image Credit: Esin Deniz, Shutterstock

How Do Cats Catch It?

The virus lives in the environment for long periods of time. So, a cat can be directly exposed cat-to-cat or can pick it up in the environment. For example, a cat can pick it up off the sidewalk after a cat with distemper has pooped there—even months later.

How Do I Care for a Cat With Distemper

The disease can be deadly and will usually require hospitalized care for kittens to survive. By providing intensive supportive therapy the body will hopefully have a chance to fight off the infection. All cats with distemper will need to be isolated in a veterinary hospital.

Cats will need intensive treatment and ICU care. This will possibly include but is not limited to:

  • IV fluid therapy
  • Medication
  • Pain management
  • Nutritional support
  • Fever management
  • Antibiotics (in some cases)
cat treated in vet clinic
Image Credit: Raihana Asral, Shutterstock

divider 3 paws

Frequently Asked Questions (FAQ)

When Should Kittens Receive Their Vaccination?

The panleukopenia vaccine is considered one of the main core vaccines for kittens. The vaccine will need to be boosted one month apart for both adults and kittens. Kittens should start receiving their vaccine as young as 6–8 weeks old. Bring your kitten back for boosters once every 3–4 weeks until they are old enough.

If you are unsure of how old your kitten is, still bring it in for a vaccine and discuss the situation with your vet. Once fully vaccinated, your cat will need a booster once a year or once every 3 years, depending on the vaccine brand.

Veterinarian giving injection to cat
Image Credit: Africa Studio, Shutterstock

How Would an Indoor Cat Catch Distemper?

The feline panleukopenia virus is very resistant and can survive for long periods in many environments. It is even resistant to many disinfectants. So, it can easily be picked up on your shoes or clothing and brought indoors to your cat.

Are There Other Diseases with Similar Signs?

Many diseases start with lethargy as the first sign and progress to dehydration and GI signs. So, it will be important for a veterinarian to confirm the diagnosis of panleukopenia while also providing medical support. Some other possibilities could include:

How Is Distemper Diagnosed?

A vet will correlate the signs of distemper, including dehydration and fever, with changes in the blood. Because the immune system is infected the white blood cell count will be low. There is also a PCR or antigen test that can be performed on the feces to confirm an infection.

cat examined by Vets
Image Credit: Kzenon, Shutterstock

divider 3 paws

Conclusion

The most important thing to remember about distemper in cats is that it’s very contagious, and all kittens, indoors and outdoors, should be vaccinated against it. It is a severe illness that often requires your kitten to stay in the hospital for days, and it’s very possible that your kitten may not survive. This is why vaccination is so vital, as well as recognizing the signs and acting quickly if you suspect infection.


Featured Image Credit: Kginger, Shutterstock

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything cat

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.

How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Catster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.

Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

My Cat Wants to Be Alone All of a Sudden: 8 Vet Approved Reasons

Cats have a way of getting their alone time whether we want to give it to them or not. Whether your cat is...

13 Quiet Cat Breeds That Don’t Meow a Lot (With Info & Pictures)

Cats are independent and courageous. They’ll spend hours snuggled up in your lap while you are lounging around on the couch. They will...

Can Cats Get Colds? Vet-Approved Signs & Treatments

Cat colds exist, but they are most often referred to as upper respiratory infections. Cats can get some of the signs of a...

Iris Melanosis in Cats: Vet-Verified Signs, Causes & Treatment

A cat’s eyes are often their most striking feature. We all know whether our cats have amber or green irises and are fairly...

More related

National Specially-Abled Pets Day 2025: When and What Is It?

Owning a specially-abled pet is life life-changing in all the best ways. They show us so much love and acceptance and understandably we...

When to Euthanize a Cat With Feline Leukemia: Vet-Reviewed Advice

Feline leukemia is a serious disease that can cause a wide range of signs in cats, including anemia, weight loss, and infections. Unfortunately,...

7 Creative, Crafty Uses for Cat Hair (With Pictures)

While hair floating around the house can be the bane of many cat parents’ lives, those fluffy bundles can be more useful than...

Why Does My Cat Have Whiskers on Their Eyebrows? Vet-Verified Facts & Functions

Though whiskers above the mouth are a standout feature in cat anatomy, whiskers in other areas are less conspicuous. In addition to the...

Keep reading

How To Get a Stool Sample from a Cat: 4 Vet-Reviewed Steps

Regular fecal testing is an important aspect of preventative care for cats, and an essential diagnostic tool if your feline is feeling under the weather. If your veterinarian asks you to provide a stool sample for your cat, however, it...

cat poop in litter box

11 Best Cat Foods in Canada in 2025 – Reviews & Top Picks

Did you know that around 50%-60% of Canadian pets are considered obese?1 Obesity is a serious health concern for cats as it increases their risk of developing potentially life-threatening conditions like cancer and heart disease.2 The good news is that...

grey cat eating food

Why Do Cats Clean Themselves So Often? 12 Vet-Verified Reasons

When you own a cat, you notice their strange habits and may try to determine what they’re thinking. However, deciphering a feline’s intentions is challenging. Cats are complex creatures, but their odd habits have a purpose. They spend plenty of...

a domestic tabby cat licking its paw

Domestic Shorthair Cat Health Problems: 15 Vet-Verified Issues

Domestic shorthair cats are the perfect pet for people who want a small, easy-to-care-for animal that doesn’t require a lot of exercise. These cats have a sturdy build and average weight of around 6 to 8 pounds, making them the...

Catster_Health Problems of Domestic Shorthair

10 Best Flea Drops for Cats in 2025 – Reviews & Top Picks

Providing solid flea protection for cats is vital. Flea bites cause itching and make cats scratch and bite themselves, which can lead to skin infections. These tiny parasites can transmit disease-causing bacteria and tapeworms to cats. Fleas are so problematic...

Woman injecting cat product to prevent from flea treament

Are Irises Poisonous to Cats? Vet Approved Facts & Safety Tips

You likely know how it feels when you discover that your cat has eaten something and you have no idea whether it’s safe. Things that kitties seem quite fond of include plants and flowers, which are common in households. While...

Catster_Are Irises Poisonous to Cats

7 Best Calming Aids for Cats in 2025 – Reviews & Top Picks

Cats can benefit from calming aids for a variety of reasons. If you have a cat that is particularly nervous, overly energetic, stressed, or frightened from external factors such as thunderstorms, then using a calming aid for your cat can...

6 Health Risks of Keeping a Dirty Litter Box: Vet-Approved Sickness Signs

Cleaning the litter box is one of the most laborious (not to mention smelly) tasks a cat owner must do every day, so it’s easy to let this job slide to the wayside. But did you know that slacking on...

woman cleaning cat litter