Get

In Your Inbox

Catster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

Persian Cat Health Problems: 6 Vet-Reviewed Issues 

Catster_Health Problems of Persian Cats

The beautiful Persian cat is known to be quiet and docile. They are easily recognized by their flat face, full cheeks, short muzzle, and big round eyes. This long-haired breed is quite popular, with a history dating back thousands of years in ancient Persia.

While the Persian cat is beautiful and sweet, they are prone to developing certain genetic health problems, just as we humans can inherit particular diseases. Many of these cats do enjoy long, healthy lives, but if you have one of these mellow and charming felines, you should still familiarize yourself with common Persian health issues so you’re not surprised by unexpected veterinary bills later.

Here are the most common health issues that Persian cats can have. This way, you’ll know what your feline friend may be susceptible to.

divider 2 cats

The 6 Common Persian Cat Health Problems

1. Polycystic Kidney Disease (PKD)

Persian Cat and tree
Image by: lindarczyk, Pixabay

Polycystic kidney disease (PKD) is an inherited condition in which fluid-filled cysts develop in the kidneys. These cysts are present from birth and tend to multiply and grow larger over time, wherein they end up causing kidney failure. Of all the cat breeds in the world, Persians have the highest incidence of PKD, which affects about one in every three Persians.

PKD is caused by a gene abnormality that’s evident primarily in Persians, though other breeds may have it, like the Himalayan and British Shorthair breeds. PKD signs typically develop when a cat is around 7 years old.

Signs:
  • Increased drinking and urination
  • Diminished appetite
  • Weight loss
  • Nausea
  • Vomiting
  • Lethargy

How Polycystic Kidney Disease Is Diagnosed and Treated

When PKD disease was first recognized, the only way to identify it was an ultrasound of the kidneys. Nowadays, there is a genetic test available to detect PKD.

If you take your Persian to the vet because you suspect they have PKD, a vet will conduct a physical examination and see if your cat’s kidneys feel enlarged. The vet will also check your cat’s blood and urine for signs of the disease.

There is no cure for this inherited progressive disease, but the signs can be managed. If your Persian has PKD, a vet will cater their treatment according to the progression of the disease. The treatment may include antibiotics, fluid therapy, appetite stimulants, dietary plans, or pain medications—it all depends on how advanced the PKD is.


2. Progressive Retinal Atrophy (PRA)

Persian cat looking out the window
Image Credit: NTP_RASTA, Shutterstock

Persians are predisposed to progressive retinal atrophy (PRA), which is a term used to describe a group of degenerative eye diseases affecting the retina. There are two main types of feline PRA: early-onset PRA, which affects kittens, and late-onset PRA, which affects adult cats.

This progressive eye condition is caused by the abnormal development of the retina’s photoreceptor cells, which can lead to total blindness. PRA is a hereditary eye disease first recognized in the Abyssinian cat breed. This inherited disease is known to affect Persians, as well as many other popular cat breeds, including Siamese, Peterbalds, and Bengals.

Signs:
  • Uncoordinated eye movements
  • Eyes that appear shinier than normal
  • Night blindness
  • Reluctance to go outside or venture into dark rooms
  • Bumping into items when walking, especially at night

How Progressive Retinal Atrophy Is Diagnosed and Treated

If you take your Persian to the vet for suspected PRA, the vet will examine the back of your cat’s eyes to see if there are abnormalities of the optic nerve and blood vessels of the retina.

If your cat is diagnosed with PRA, the vet will likely treat your cat with antioxidant supplements and vitamins. It’s also possible that your cat receives treatment for cataracts or retinal detachment to help safeguard what vision they have left.


3. Brachycephalic Airway Syndrome

Portrait of a beautiful persian cat
Image Credit: Irina oxilixo Danilova, Shutterstock

Brachycephalic airway syndrome is a term used to describe an abnormality that blocks the airway of brachycephalic cats. A Persian is such a cat because they have a face and nose with a pushed-in appearance. Because a Persian has shorter bones of the face and nose, this breed is susceptible to breathing problems.

It’s common for a brachycephalic cat like a Persian to have an elongated soft palate that partially blocks the windpipe. Also common are narrowed, small nostrils that restrict the airways. Both of these upper airway problems can lead to issues with inhaling.

Over time,  since they have trouble breathing, a cat with brachycephalic airway syndrome can develop more problems, which may include heart issues due to an increased amount of strain on the muscle.

Signs:
  • Mouth breathing
  • Snoring
  • Noisy breathing
  • Coughing or gagging
  • Easily tired after exercise

How Brachycephalic Airway Syndrome Is Diagnosed and Treated

If you see any signs of brachycephalic airway syndrome in your Persian, a vet will conduct a physical examination to inspect the structure of your cat’s face. They will likely also run some blood work and take chest X-rays.

If your cat has this syndrome, surgery of the stenotic nares is typically the treatment used, which involves removing tissue from the nostrils, allowing for better airflow. The surgery may also include shortening the soft palate to a normal length if it’s found to be elongated.


4. Dental Disease

Chinchilla Persian Cat
Image by: Image Credit: IceEye, Pixabay

Since the Persian is a flat-faced, brachycephalic cat breed, they are susceptible to dental disease, which includes periodontal disease (gum disease). Dental disease is common in cats that don’t have their teeth brushed regularly.

Dental disease typically starts with tartar building up on the visible part of the teeth, gradually leading to diseased gums and roots. This is why it’s always recommended to brush a cat’s teeth—they can’t do it themselves! By simply brushing your Persian’s teeth with regularity, you can help your little furball avoid losing their teeth and developing more serious problems.

Signs:
  • Mouth pain
  • Bad breath
  • Reduced appetite
  • Weight loss
  • Difficulty eating
  • Drooling
  • Bleeding teeth or gums

How Dental Disease Is Diagnosed and Treated

If you take your Persian to the vet because you suspect they have dental disease, a vet will examine your cat’s mouth to look for signs of infection. However, a complete evaluation is only possible under anesthesia with dental probing and full-mouth dental X-rays.

If your cat has dental disease, there are several treatment options. The vet may prescribe an anti-inflammatory pain reliever or antibiotics if there’s an infection present. It’s also possible that your cat will need to have their teeth extracted to prevent an infection of the jawbone.


5. Idiopathic Seborrhea

White persian cat walking on green grass
Image Credit: ANURAK PONGPATIMET, Shutterstock

Persian cats are known to have a skin disorder called idiopathic seborrhea. This is a condition that is characterized by red, irritated, and itchy skin and the overproduction of an oily, waxy substance produced by the skin glands. A cat with idiopathic seborrhea will have clumpy, stinky fur and will scratch a lot.

Idiopathic seborrhea may be inherited or caused by allergies, dietary problems, endocrine disorders, fungal infections, or parasites.

Signs:
  • Red or irritated skin
  • Itchiness
  • Clumpy, smelly fur

How Idiopathic Seborrhea Is Diagnosed and Treated

If your Persian is at the vet for a suspected case of idiopathic seborrhea, a vet will conduct a physical examination to check for anything that’s causing the itchy red skin, like parasites. Blood and skin tests may also be conducted to determine the cause of the disease.

While there is no cure for idiopathic seborrhea, the management of this condition can be successful. The vet may recommend a special cat shampoo to control the oily buildup or prescribe a supplement or oral vitamin. If your cat develops a secondary infection, antibiotics or antifungal medications may be prescribed.


6. Heat Sensitivity

Persian
Image by: Mariamichelle, Pixabay

Because Persians have a thick, dense coat and a flat face that makes it harder to pant, these cats are prone to heat sensitivity. If a heat-sensitive Persian can’t cool off, heat exhaustion can occur and may lead to more serious heatstroke. Heat exhaustion is a precursor to heatstroke, which can cause a cat to collapse, have seizures, or slip into a coma.

Signs:
  • Excessive panting
  • Drooling
  • Rapid breathing
  • Lethargy
  • Red tongue or mouth
  • Vomiting
  • Staggered gait

How Heat Sensitivity Is Diagnosed and Treated

If you suspect your Persian is suffering from heat sensitivity, the vet will take quick action. After assessing your cat’s signs and checking their body temperature, the vet may give your cat fluids intravenously if dehydration is suspected. The vet will also likely put your cat in a cool room and monitor their breathing before allowing them to go home.

If you suspect that your cat is suffering from any of the above, it’s best to contact a vet for more information and determine your next steps.

divider 2 cats

Tips for Keeping Your Persian Healthy

Since we know that you want your Persian to be healthy and happy, we outlined the six most common health problems this breed faces. To help keep your Persian healthy, use common sense. Keep tabs on your cat’s diet to ensure they’re getting all the nutrients they need, and provide them with plenty of exercise opportunities.

To keep your Persian’s teeth and gums healthy, pick up a cat toothbrush and some toothpaste so you can clean those pearly whites. You should plan on brushing your cat’s teeth three times a week at least!

It’s just as important to groom your long-haired Persian using a cat brush. You should get into the habit of brushing your Persian every day to keep their fur mat-free. While you’re grooming them, take a look at their ears for wax, debris, or signs of infection, and clean them using a damp cloth.

Finally, you should always make sure that your Persian has access to lots of drinking water, especially during the summer months.

divider 2 cats

Conclusion

Even though Persian cats are prone to developing some serious health issues, many Persians live long and healthy lives. To help your beautiful feline live a full life, provide them with the best care possible and work closely with a vet. Together, you and a veterinarian can safeguard your Persian’s health so you’ll have your little buddy around for a very long time.


Featured Image Credit: Santi Nanta, Shutterstock

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything cat

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.

How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Catster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.

Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

What’s the Price of an Ultrasound for a Cat? 2025 Guide

Veterinary care can be expensive. Whether your cat needs an ultrasound for reasons related to pregnancy or a medical condition, there can be...

How to Deworm Feral Cats: 4 Tips & Tricks (Vet Answer)

Deworming cats can be challenging at the best times, especially if they are feral. Cats have the marvelous ability to turn into agile...

10 Best Flea Combs for Cats in 2025 – Reviews & Top Picks

Caring for your feline friend involves more than just feeding them and ensuring they get regular check-ups. One major aspect of pet care...

Is Lethargy Normal After Surgery In Cats? Vet Approved Care & Health Facts

Whether it’s a routine operation or major surgery, cats need time to recover after any surgical procedure. They need extra care and attention,...

More related

14 Signs a Stray Cat Likes or Dislikes You (Vet-Reviewed)

Many people have a few cats that tend to hang up around their houses. Maybe they gather under your front porch or show...

100+ Greek Cat Names: Ideas for Strong & Legendary Cats

When most people think of Greece, they are transported to the Acropolis or the ocean, and the homes are perfectly sculpted from the...

Is Hand Soap Toxic to Cats? Vet-Reviewed Risks & Alternatives

Sometimes, our cats like to stick their noses where it doesn’t belong and taste our deliciously scented cucumber watermelon hand soap. Or maybe...

Why Are Cats Afraid of Cucumbers? Our Vet Explains

Videos of cats getting frightened by cucumbers abound online. They usually follow a vaguely similar pattern; a pet parent puts a cucumber behind...

Keep reading

Why Does My Cat Lie on Me? 5 Vet-Reviewed Reasons

We all love to spoil our cats, so they tend to get new toys and tasty treats more often than we do! Seeing them napping in odd spots around the house inspires many cat owners to purchase a special cat...

cat sleeping in owner's arms

How Does My Cat Know When I Wake Up? Morning Habits Explained

Cats are naturally reclusive creatures that like to keep to themselves. But once they find owners worth loving, they can’t get enough of them. If you’re lucky enough to have a cuddly cat, they’ll likely curl up with you in...

teenager cat owner cuddling with pet cat

Can Cats Eat Caramel? Vet-Reviewed Facts & FAQ

Let’s face it: cats are weird creatures. They surprise us with all sorts of quirky behaviors every single day. Your cat might ignore a delicious meaty dish of wet cat food, but you’ll find their head stuck in a bag...

Can Cats Eat Caramel

How to Tell Cat Gender By Face? 3 Vet-Approved Ways

Male and female cats can have physical and behavioral differences. Additionally, each faces its own unique health challenges, which can make it essential to know what sex you’re adopting. The only 100% reliable way of knowing a cat’s sex is...

close up amber smoke norwegian forest cat

How To Keep Your Cat From Jumping After Surgery: 10 Vet-Approved Tips

There can be many reasons why your cat has undergone surgery, and we bet you’re just happy to have them home now. Regardless of the cause, your vet provided you with post-operative care instructions and may have asked that you...

cat lying on bed under the sheet

How to Help Children & Cats Bond: 9 Vet-Verified Tips

Cats and kids make great companions. Although fostering a healthy friendship can sometimes be challenging, it is much easier when you start by making proper introductions. Children, especially those with a spirited disposition, can scare the living daylights out of...

little girl talking to cat

Can Cats Eat Gingerbread? Vet-Approved Facts & FAQ

Gingerbread is a tasty holiday treat that people around the world enjoy. The sweetness and the zing of ginger produce a unique flavor profile. Unsurprisingly, you might want to share some gingerbread with your cat! Not only does gingerbread taste...

Can Cats Eat Gingerbread

8 Best Cat Foods With Taurine (2025) – Reviews & Top Picks

When it comes to selecting the best cat food for your precious feline, it can seem like there are way too many options to choose from. While most of us know that a high protein diet is important for our...

tabby cat eating from a bowl outside