Get

In Your Inbox

Catster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

Hypertrophic Cardiomyopathy in Cats (HCM): Signs, Diagnosis & Treatment (Vet Answer)

Share

sad sick cat in bed

Hypertrophic cardiomyopathy (HCM) is the most common type of heart condition witnessed in cats. When hypertrophic cardiomyopathy occurs, the muscle of the heart becomes thickened. This can prevent the heart from working efficiently and eventually lead to heart failure and death. The good news is that if it is caught early, the condition can be managed with certain types of medication.

It can be a challenging condition to diagnose as often there are no obvious clinical signs therefore it goes undetected until the disease has progressed to an advanced state.

divider cat faces 2 oct 2024

What Is Hypertrophic Cardiomyopathy?

Hypertrophic cardiomyopathy causes the heart muscle to become unusually thick. This reduces the size of the chambers of the heart making them smaller as the muscle takes up more space. This means that it is difficult for the heart to pump blood around the body effectively.

It can lead to a whole range of problems relating to the heart and circulation such as blood clots, increased blood pressure, an irregular heartbeat, heart murmurs, and eventually heart failure and death.

veterinarian holding the cat
Image Credit: H_Ko, Shutterstock

What Are the Signs of Hypertrophic Cardiomyopathy?

It can be difficult for owners to spot signs of hypertrophic cardiomyopathy in the early stages as there is often not much to see. It can go unnoticed for years. The disease usually progresses gradually so changes can be very subtle.

When clinical signs do become apparent, the typical things owners notice include:

Clinical signs may include:
  • Lethargy
  • Exercise intolerant
  • Increased respiratory rate
  • Sudden onset breathing difficulties
  • Fainting
  • Pale gums
  • Reduced appetite/completely off food
  • Fluid buildup around the abdomen
  • Increased heart rate
  • Weak pulse
  • Murmur (not always present)
  • Signs of thromboembolism (Loss of use of both or one hindlimb)
It is worth noting that some cats live for years without developing any clinical signs. In some cases, cats will never develop signs and in other cases, cats will experience sudden death with no prior warning.

What Are the Causes of Hypertrophic Cardiomyopathy in Cats?

The most common cause is an inherited disease that affects the cardiac muscle. Certain breeds of cats are more commonly affected, these include:

  • Persians
  • Bengals
  • Maine Coons
  • Norwegian Forest
  • Sphynx
  • Chartreux
  • British Shorthairs
There is a mutation in a gene often found in these breeds of cats. The gene has a role in maintaining healthy cardiac muscle. If the mutation is present, the heart muscle cells in the wall of the left ventricles die and scar tissue develops. This prevents the heart from functioning properly.

There are three different types of hypertrophic cardiomyopathy seen in cats. It can be inherited, meaning it has been passed down via genes from a parent. It can be idiopathic which means the cause is unidentified. It can also be caused by other conditions in the body such as high blood pressure or hyperthyroidism. Various medical conditions can cause hypertrophic cardiomyopathy in cats. Tumors that are present in or around the structures of the heart can cause changes in the thickness of the ventricle walls.

This disease can stimulate abnormal growth of the muscle walls of the left ventricle of the heart. A condition called acromegaly (where excessive growth hormone is secreted due to a tumor) can also cause the heart muscles to grow abnormally. Other diseases that cause prolonged high blood pressure, such as kidney disease, can put extra strain on the heart and cause the walls to thicken. This is because the heart has to work harder to pump blood around the body when the blood pressure is higher. Over time, the muscles undergo changes as their workload increases.

ginger persian cat lying on the floor
Image Credit: CKYN stock photo, Shutterstock

Diagnosis of Hypertrophic Cardiomyopathy in Cats

A vet will begin by performing a full physical exam and taking a clinical history from you. They will pay particular attention to the lungs and heart, listening for any abnormal heart sounds such as arrhythmias and murmurs. A blood test will be taken to assess white and red blood cell counts and to monitor organ function. Thyroid levels will be checked too. This is to rule out any pre-existing health issues that may cause hypertrophic cardiomyopathy.

A specific blood test can be done to screen for raised heart biomarkers such as a chemical called pro-BNP. This increases when the heart muscle undergoes any trauma or is stretched.

In some cases, X-rays are useful. However, the inside of the heart cannot be properly assessed using radiographs so the changes associated with hypertrophic cardiomyopathy can sometimes be overlooked or not seen because they aren’t visible on the X-rays. Electrocardiograms can be used to assess the rate and rhythm of the heart.

For a definite diagnosis of hypertrophic cardiomyopathy, an echocardiogram can be performed. This is an ultrasound scan of the heart that allows the vet to assess the architecture of the heart and any changes in the structure. The blood flow in and out of the heart and between the chambers of the heart can also be assessed. Your cat’s blood pressure will also be assessed and monitored.

If you are concerned or have questions about your cat’s health, you can also speak to a vet from the comfort of your own home to help make a plan. They can determine when an in-clinic vet visit should be made.

If you need to speak with a vet but can't get to one, head over to PangoVet. It's an online service where you can talk to a vet online and get the advice you need for your pet — all at an affordable price!

PangoVet_Mention-in-Content for PangoVet2 save money

How Do I Care for a Cat with Hypertrophic Cardiomyopathy?

Treatment options for cats with hypertrophic cardiomyopathy depend on how severe the disease is and how far it has progressed. If your cat has no clinical signs, and they generally seem fit and well, it may be the case that the vet advises you to monitor them closely at home.

A vet will need to examine your cat regularly to check them over and see if the disease is progressing. These checkups will include heart scans to allow the vet to measure the side of the ventricle walls on a regular basis. When cats are not displaying clinical signs, they may still benefit from medication that can prevent blood clots from forming.

If your cat is showing clinical signs, there is a wide range of medications that can be prescribed by the vet. These include:

These include:
  • ACE inhibitors: These drugs reduce the blood pressure therefore making it easier for the heart to pump blood around the body.
  • Diuretics: These help flush out excess fluid that builds up in the abdomen and the lungs which is commonly seen if the heart is not pumping as efficiently.
  • Inodilators: These drugs help the heart to pump more effectively. They increase the function of the left side of the heart when the heart is forcing blood out into the aorta. This is the main artery that supplies oxygenated blood to the rest of the cat’s body.
  • Beta Blockers: These can be used to slow the heart rate down and correct disruptive arrhythmias (when the heart has an irregular rhythm) that may be occurring. Beta-blockers can also decrease blood pressure and improve the functioning of the valves in the heart.
  • Anticoagulants/anti-clotting Drugs: These are prescribed to reduce the risk of blood clots forming. This is very commonly seen in cats with hypertrophic cardiomyopathy.
  • Calcium Channel Blockers: These medications can reduce the thickness of the left ventricle wall and prevent fluid buildup.
If cats present in respiratory distress, they will require emergency stabilization including oxygen supplementation. In some cats with more advanced diseases, it is necessary to drain fluid from the lungs at regular intervals. This is called . It is often necessary to sedate cats to keep them calm as stress can exacerbate the condition.

vet checking bengal cat
Image Credit: Pressmaster, Shutterstock

divider cat faces 2 oct 2024

Frequently Asked Questions (FAQ)

Is there a cure for hypertrophic cardiomyopathy?

Sadly, there is no cure for hypertrophic cardiomyopathy. It is a progressive disease and as the structure of the heart alters, clinical signs will start to develop. Some cats with mild disease can lead a relatively normal life. but in severe cases, it can be a debilitating condition and the cat’s quality of life is compromised.

There are lots of different management options that can help to alleviate clinical signs and make your cat feel more comfortable, but unfortunately, there is no cure.

How can I help my cat with hypertrophic cardiomyopathy at home?

Cats with hypertrophic cardiomyopathy must not be allowed to become overweight. If this occurs, this will put more strain on their already overworked cardiovascular system.

Reduce stress if at all possible around your home. Stress can cause breathing issues and increase the risk of heart failure.

One of the most important things owners can do at home is to monitor their breathing rate when they are at rest. It should always be less than 55 breaths per minute. If it gets higher than 55, contact a vet immediately as this is a sign their heart is not doing its job properly.

woman relaxing with her tabby cat on a sofa
Image Credit: U__Photo, Shutterstock

Can hypertrophic cardiomyopathy be prevented in cats?

As the disease can occur due to the presence of other health conditions, or be inherited, in many cases it cannot be prevented. Screening tests can be done for mutations in the A31P gene that causes abnormalities. Responsible breeders should not breed cats with the gene. Cats with other medical conditions or cats that are high risk should be screened regularly for heart disease.

divider cat faces 2 oct 2024

Conclusion

Hypertrophic cardiomyopathy is the most common heart disease seen in cats. The majority of cases are subclinical. This makes it a challenging disease to manage. If you are concerned about your cat being at risk of hypertrophic cardiomyopathy or are worried that the disease may be progressing, make an appointment with a vet.

They will be able to assess the risk factors and carry out appropriate diagnostic tests if required. If your cat has already been diagnosed, they will be able to advise on treatment and management options to make your cat as comfortable as possible.


Featured Image Credit: Julia Cherk, Shutterstock

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything cat

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.




How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Catster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.


Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

The Cat Biting Mistakes Most Owners Make (And What Works Instead)

Cat bites sent more than 400,000 people to emergency rooms in the US each year.1 Not scratches. Bites. And the reason they’re so...

Do Cats Cause Schizophrenia? Scientists Find a Link – Here’s What It Means

Being a fierce advocate (and occasional recipient of) mental health support and awareness, the term ‘crazy’ is not one I like to fling...

One in 100 Cats Gets Diabetes – Here’s How to Catch It Early

One in every 100 cats develops diabetes.1 That’s not a rare, unlucky condition reserved for cats with obvious health problems. It’s common enough...

Dramatic Rescue Turns Into Dramatic Reunion

What started as a routine call for the RSPCA became a heroic, five-hour rescue featuring one trapped and traumatized cat, an emotional family...

More related

Can Cats Drink Tap Water? Vet Approved Facts & FAQ

As humans, we have so many options when it comes to what to drink each day. Coffee for breakfast (or all day), juice,...

7 Best Outdoor Heating Pads for Cats in 2026 – Reviews & Top Picks

When colder temperatures roll around in the winter, it can be hard on our outdoor pets. This is particularly true of cats, who...

6 Best Cat Window Guards & Screens In 2026 – Reviews & Top Picks

Cats love to sit on windowsills and watch the birds (or the neighbor’s cat). Some cats may even love the idea of going...

How to Introduce a Kitten to a Cat: 10 Vet-Approved Tips

Bringing home a new kitten is an exciting time for any cat owner, but if you already have a cat, you’ll need to...

Keep reading

Can Cats Eat Pine Needles? Vet-Approved Risks & Alternatives

If you want to celebrate Christmas with a beautiful pine tree in your house, but you also own a cat or two, you know how tricky this can be. Beyond the usual hazards of your cat vs. the Christmas tree,...

Can Cats Eat Pine Needles

How To Stop a Cat From Putting Their Paws In Their Water: 3 Tips & Tricks

Cats are often considered incredibly water averse, which probably brings a smile to any cat companion who’s watched their buddy become mesmerized by a flushing toilet or transfixed by water dripping from a faucet. Splashing in water bowls is a...

cat dipping its paw in water bowl

Can Cats Be Trained Like Dogs? Vet-Approved Tips & Tricks

Cats are independent creatures that like to do things on their own terms. However, they are also highly intelligent and can learn to do many things that we want to teach them. But can cats be trained like dogs can?...

young woman training cat in the kitchen

Colitis in Cats: Our Vet Explains Signs, Diagnosis & Treatment

Taking care of a cat experiencing gastrointestinal symptoms can be quite an ordeal and cause a significant amount of stress for both you and your cat. A gastrointestinal sign that may impact your cat and make them feel ill is...

A cat having a check up at a small animal vet clinic

Can You Put a Flea Collar on a Pregnant Cat? Vet-Reviewed Precautions & Risks

Cat flea collars use a form of insecticide to repel, deter, or kill fleas. They can be used in conjunction with spot-on treatments or independently, though owners do need to be aware of the potential risks associated with flea collars....

Collar for animals protecting against fleas

Does Cold Weather Kill Fleas on Cats? Vet Approved Advice

Do fleas die in winter or cold weather? According to Athens Animal Wellness Center1, fleas can survive for up to 5 days in temperatures as low as 46 degrees Fahrenheit. That means unless you keep your house at sub-50 temperatures,...

close up flea on a cat

8 Best Wet Cat Foods in Australia in 2026 – Reviews & Top Picks

There are many benefits to introducing wet cat food into your cat’s diet. It contains more moisture to help your cat stay hydrated, and it’s easier to eat and digest for older cats and cats with digestive issues. However, even...

orange cat eating wet food

Why Do Cats Twitch in Their Sleep? 3 Vet Reviewed Reasons

Just like people and other animals, you may notice that your feline sometimes twitches in their sleep. As you might guess, this is pretty normal behavior. Lots of cats twitch in their sleep, though some are more prone to this...

Fat Calico Cat Lying or sleeping on a Perch in the Window sunbathing

Love Cats? So Do We! Join the Catster Community

Stay informed with expert pet care insights delivered straight to your inbox! Discover professional guidance on animal behavior, feeding tips, trusted product picks, and much more.




Sign up for the Catster Email Newsletter

Stay informed with expert pet care insights delivered straight to your inbox! Discover professional guidance on animal behavior, feeding tips, trusted product picks, and much more.