Feline Eosinophilic Granuloma

This forum is for cat lovers seeking everyday advice and suggestions on health-related issues. Remember, however, that advice on a public forum simply can't be a substitute for proper medical attention. Only your vet can say assuredly what is best for your cat.


Rei- evil cutie
Purred: Sat Mar 29, '08 7:53am PST 
I went to the vet today due to my paws. They've been dry ever since I came to live at this home, but the past few months, some of the paw pads have turned a purplish color and have become puffy. I still do everything normally. They don't bug me at all. I'm still a happy kitty and acting normal.

My humans wanted to get my paws checked on anyway, though. frown

The vet checked my feet and told my humans that it could be a number of things. He believes it to be a disease found only in cats called Feline Eosinophilic Granuloma. If not that, it's auto immune or worse, something metabolic.

He gave me a Prednisone shot (which HURT!) to treat Feline Eosinophilic Granuloma. It also treats auto immune disease so that's good, too. If it doesn't work within a week though, I have to get blood tests and a paw pad biopsy. I sure do hope it's Feline Eosinophilic Granuloma.

My humans came home and went online and started looking it up. If anybody else wishes to find out about Feline Eosinophilic Granuloma, just go to any of these places:

http://www.marvistavet.com/html/eosinophilic_granuloma.ht ml
http://www.buzzardsbayvetassociates.com/Feline%20Eosinophilic%20 Granuloma%20Complex.htm

Well, I hope this gets better. I hate going to the vet and hate shots even more. Sad thing is, I may need more shots throughout my life since this may be a long term thing. I may not need them though since it doesn't bug me. There's always hope.


On the Prowl....
Purred: Sat Mar 29, '08 7:17pm PST 
I hope you're feeling better soon!! hug


Devilish- Darling!
Purred: Sat Mar 29, '08 11:30pm PST 
hello rei,

sorry to hear your having some problems, I had to reply to your post as I just didnt feel comfortable as to what your vet has told you, at an instant the disease mushy pad disease/pillow foot jumped out at me, im no vet, im a simple cat with only the knowledge I have learnt along the way.
please take a look here http://www.marvistavet.com/html/body_plasma_cell_pododermatitis.html
Of course I might be right of target here but I am sure you are aware that Eosinophilic Granuloma is rather common in cats with skin problems and similar and being that your problem is paw related I felt it leant more towards this disease. Also keep in mind that our vets are NOT specialist at things like this they can only guide us with their basic skills.
I do wish you the best of luck and hope you recover quickly.

D-Max...In- Loving- Memory

One Eyed Wonder
Purred: Sun Mar 30, '08 6:52am PST 
Purrs Rei...

Mom and I know nothing about your disease and Jordan made some very good points...Having purred that I want to add something for you and anyone else who is using prednisone...

A very very red warning flag went up for me when I saw that you got a prednisone shot...Prednisone is a very dangerous drug..Please be very careful with this...I Also wonder why the blood work was not done BEFORE giving the prednisone shot?????

A one time use is ok but this should not be given long term..PLEASE have your Mom ask about side efects from this..It does not cure immune system problems....It is a mask to the cause of the problem..It will cover the symptoms for a short time but the problem is still there...

Prednisone given long term damages your liver and your kidneys...If you have a weakened immune system its use only weakens it more as the doses of prednisone become higher and more frequent...

Prednisone and other steroids should never be given on a regular basis..Any of you on them now please talk to your vet and get weaned off of them....I was on depo and prednisone for my FIP...After Mom got educated as to what it was doing to me she turned to alternative ways to strengthen my immune system through better diet and supplements under the guidance of a homeopathic vet...

Purrs that you are soon feeling better...

An excerpt from www.nativeremedies.com/petalive

Prednisone is a synthetic corticosteroid. It belongs to the glucocorticoid class. The effectiveness of the use of prednisone as a veterinarian medication depends upon the dosage prescribed. Different doses are used for different conditions:

Low doses are mainly used for inflammatory conditions, like allergies.
Moderate doses are used as appetite stimulants and antiemetic agents (prevents vomiting and nausea).
High doses are used during chemotherapy treatment for cancer and for treatment of immune and auto-immune related diseases, like ulcerative skin diseases.
Corticosteroids are also used for treating certain disorders like inflammatory bowel diseases, intestinal lymphoma, and adrenal or pituitary tumors in cats. They are also dependable and provide quick relief. The superior capabilities of this drug have lead to abuse. Pet owners are prone to look for short cuts and resort to giving a large dose of prednisone at the mere sight of any illness. Further, prednisone is not devoid of side effects. Although it relieves the symptoms of the ailment, it can cause many other issues to surface.

Since cats require higher doses of prednisone for desired results, they are most likely to face maximum side effects from the drug. The nature of the side effects depends on the period for which it has been ingested. If prednisone is ingested for more than seven days, there is a chance that the cat may become dependent on the drug. Long term use suppresses the natural adrenal function and abrupt discontinuation of prednisone can cause serious ailments. There are other effects of prednisone, as listed below:

Short term effects

Increase in high blood pressure, particularly in diabetic cats
Fluid retention
Renal disorders and increased urination
Excessive thirst
Poor coat quality
Gastrointestinal ulcers and disturbances, such as vomiting and diarrhea
Muscle degeneration
Behavioral changes
Long Term effects

Eye disorders
Weight gain
Cushing’s Disease


Lazy, Lazy, Lazy
Purred: Sun Mar 30, '08 10:24am PST 
D-Max, while I have to agree with you on some of your points, I also must disagree with you on, several as well. Prednisone should never be used in lieu of other medicines and without thorough testing to determine the exact cause of the problem. However, there are certain conditions that require the use of prednisone and you may be endangering the lives and/or quality of lives of these animals by telling them to stop. If they are to stop, checking with a vet is important as is weaning off of the drug. NEVER just stop giving this drug. Extreme care must be taken when stopping prednisone therapy. If an animal has been on prednisone for an extended period of time, slow weaning off the drug is critical to avoid serious complications.

In some situations, inflammation is dangerous and leads to severe damage in tissues and organs. Also, the immune system, often for no apparent reason, can attack the body and cause great damage or even death.

Some examples: treatment of bronchial and lung diseases, skin diseases, intestinal diseases, spinal cord and brain diseases and diseases of the blood.
It is often a supplemental treatment for various cancers.
It is required as a supplement in the adrenal gland disorder, Addison's disease (hypoadrenocorticism).
It is used as a treatment in bacterial (endotoxic) shock.
Prednisone is used to treat a variety of immune system and autoimmune disorders .

Please don't be overly scared of Prednisone. It is widely used and vets are trained to use the lowest possible dose to achieve the affect needed.
I would however, consult a new vet if all your vet ever wants to go is give you a steroid shot without determining the exact cause of the problem. In skin situations, it's best to consult a dermatologist.

(left hand menu will allow search for a dermatologist in your area)


Rei- evil cutie
Purred: Mon Mar 31, '08 4:59pm PST 
First off, I'm glad to say that the shot seems to be working. The pads that were effected are now going down in size and are their normal pink color. This means no needing to get tested. Thank goodness.

Also, I didn't get blood work done before getting the shot because the blood work is to find out if it is metebolic. If the shot didn't help, he would have done blood work. If that gave no answers either, I would have had a pad biopsy to figure out what is wrong. Luckily, the shot's working so it's either autoimmune or Feline Eosinophilic Granuloma (which are both treatable by the shot).

And the vet did explain everything to my humans. My one human's even a nurse and followed along very well and knows about this drug and all. I don't have diabetese, so the shot was a-okay to give to me. It did make me a bit hungry, but that's nothing big. And I didn't start acting all goofy like some cats do (humans usually do after given it). There also was not a lot given. And for all I know, I put the wrong drug. I'll have to have my human find my papers and make sure they didn't put the wrong thing down. And either way, I'd only be taking 1 to 2 shots a year since it's not bugging me at all rather than getting 1 every other month.

Anyway, my paws are looking much better. I'd say I feel much better, but I never felt bad big grin

Thanks for all your concern though.


Edited by author Mon Mar 31, '08 5:03pm PST