|Purred: Mon Jul 7, '08 5:48am PST |
|Not everything in medical research and testing can be done with non-animal methods. And with rabies having a 100% fatality rate for humans AND our beloved cat and dog companions, the FDA is going to demand a rubber-meets-the-road, conclusive, live animal trial.
Over the last two decades, the use of animal testing has been reduced a lot. Every major pharma company has procedures in place to identify non-animal methods that can substitute for animal methods with scientific validity. They also have animal care committies with community representatives (i.e., animal welfare people who aren't employed by the company) to oversee care of the animals that are used.
But those non-animal methods still mostly replace animals in the earlier stages of research, the is it toxic/how toxic/is it likely to have useful pharmaceutical effect. It means that there's a lot less "wasted" animal testing, of things that aren't going to have any use. In the end, nothing can be approved for use by the FDA without being tested on the species it's going to be used in. If they want to prove that rabies vaccine produces five-year or seven-year immunity in dogs, they have to test it--in dogs.
And if they were going to approve something without testing, it wouldn't be a rabies vaccine or an extended rabies vaccine protocol. That's because rabies does have that 100% fatality rate, in humans, dogs, and cats.
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